Patents Examined by M. S. H. Gabilan
  • Patent number: 5110823
    Abstract: Pyrrolidine derivatives of formula (I) are disclosed. ##STR1## wherein the ring A represents the following heterocyclic ring ##STR2## The compounds of formula (I) are useful as nootropic agents.
    Type: Grant
    Filed: February 26, 1991
    Date of Patent: May 5, 1992
    Assignee: Nisshin Flour Milling Co., Ltd.
    Inventors: Fumiko Hamaguchi, Tatsuo Nagasaka, Rie Hakamada, Einosuke Sakurai
  • Patent number: 5110934
    Abstract: Bisphenols having a pendent imide moiety, of formula (I) ##STR1## in which R.sub.1, R.sub.2, R.sub.3 and R.sub.4, which may be the same or different, are selected from hydrogen, fluorine, chlorine, bromine, alkyl of 1 to 6 carbon atoms, aryl of 6 to 10 carbon atoms, alkoxy of 1 to 6 carbon atoms and aryloxy of 6 to 10 carbon atoms; R.sub.5 is selected from fluorine, chlorine, bromine and alkyl of 1 to 6 carbon atoms, and m is 0, 1, 2, 3 or 4; and R.sub.7 is alkyl of 1 to 18 carbon atoms, aryl of 6 to 10 carbon atoms, unsubstituted or substituted one or more times by a substituent selected from fluorine, chlorine, trifluoromethyl, alkyl of 1 to 6 carbon atoms, and phenyl, or heteroaryl; are useful in producing poly(imidoarylether ketone)s and poly(imidoarylether sulfone)s which are amorphous and are soluble in readily available solvents, while displaying high glass transition temperatures and good thermo-oxidative stability.
    Type: Grant
    Filed: May 23, 1991
    Date of Patent: May 5, 1992
    Inventors: Allan S. Hay, Marko Strukelj
  • Patent number: 5110944
    Abstract: A process for preparing 5-hydroxyhydantoin which comprises oxidizing 4,5-dihydroxyimidazolin-2-one having formula (I): ##STR1## with hydrogen peroxide in an aqueous medium in the presence of a metal ion. According to the process, 5-hydroxyhydantoin is readily prepared from inexpensive starting materials.
    Type: Grant
    Filed: February 20, 1991
    Date of Patent: May 5, 1992
    Assignee: Kenegafuchi Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masahiko Yamada, Satomi Takahashi
  • Patent number: 5109014
    Abstract: This invention relates to novel N-aryl-3-aryl-4-substituted-2,3,4,5-tetrahydro-1H-pyrazole-1-carboxamide compounds which are useful as pesticides, compositions containing those compounds, methods of controlling pests and processes for preparing these compounds.
    Type: Grant
    Filed: December 10, 1990
    Date of Patent: April 28, 1992
    Inventor: Richard M. Jacobson
  • Patent number: 5107025
    Abstract: A process for the preparation of the sulphone of the formula: ##STR1## consists in reductive cleavage of azo/azoxy dyestuffs of the formula ##STR2##The invention also relates to the azo/azoxy dyestuffs mentioned.
    Type: Grant
    Filed: October 25, 1990
    Date of Patent: April 21, 1992
    Assignee: Bayer Aktiengesellschaft
    Inventor: Karl-Josef Herd
  • Patent number: 5104872
    Abstract: Compound of the general formula (I), which is useful as an agricultural and horticultural fungicide, an agricultural and horticultural fungicidal composition containing said compound, use of said composition for controlling plant disease, and process for the production of said compound: ##STR1## wherein ##STR2## shows a case in which R.sup.3 and R.sup.4 together form a cyclic substituent, and R.sup.1 and R.sup.4 are substituents disclosed in the specification.
    Type: Grant
    Filed: August 15, 1990
    Date of Patent: April 14, 1992
    Assignee: Nihon Hohyaku Co., Ltd.
    Inventors: Kenji Tsubata, Nobuyuki Niino, Katsutoshi Endo, Yoshinobu Yamamoto, Hideo Kanno
  • Patent number: 5098925
    Abstract: The present invention relates to spiroisoindolines that are antagonists at the phencyclidine receptor of the N-methyl-D-aspartate receptor complex and which are useful when such antagonism is desired such as in the treatment of neurological disorders. The invention further provides processes for preparing the spiroisoindolines, intermediates useful for their synthesis, pharmaceutical compositions containing them, and methods for their use.
    Type: Grant
    Filed: February 5, 1991
    Date of Patent: March 24, 1992
    Assignee: ICI Americas Inc.
    Inventor: Thomas M. Bare
  • Patent number: 5091575
    Abstract: A renin inhibiting compound of the formula: ##STR1## wherein A is a substituent; W is C.dbd.O or CHOH; U is CH.sub.2 or NR.sup.2, provided that when W is CHOH then U is CH.sub.2 ; R.sub.1 is loweralkyl, cycloalkylmethyl, benzyl, 4-methoxybenzyl, halobenzyl, (1-naphthyl)methyl, (2-naphthyl)methyl, (4-imidazoyl)methyl, .alpha.,.alpha.-dimethylbenzyl, 1-benzyloxyethyl; phenethyl, phenoxy, thiophenoxy or anilino; R.sub.2 is hydrogen or loweralkyl; R.sub.3 is loweralkyl, [(alkoxy)alkoxy]alkyl, (thioalkoxy)alkyl; lowerakenyl, benzyl or heterocyclic ring substituted methyl; R.sub.4 is loweralkyl, cycloalkylmethyl or benzyl; R.sub.5 is vinyl, formyl, hydroxymethyl or hydrogen; R.sub.7 is hydrogen or loweralkyl; R.sub.8 and R.sub.9 are independently selected from OH and NH.sub.2 ; and R.sub.6 is hydrogen, loweralkyl, vinyl or arylalkyl; provided that when R.sub.5 and R.sub.7 are both hydrogen and R.sub.8 and R.sub.9 are OH, the carbon bearing R.sub.5 is of the "R" configuration and the carbon bearing R.sub.
    Type: Grant
    Filed: June 10, 1991
    Date of Patent: February 25, 1992
    Assignee: Abbott Laboratories
    Inventors: Jay R. Luly, Jacob J. Plattner, Dale J. Kempf
  • Patent number: 5087724
    Abstract: A process for producing a 4-benzoyl-5-hydroxylpyrazole of the formula III: ##STR1## which comprises reacting carbon monoxide and a 5-hydroxypyrazole of the formula II: ##STR2## with a substituted benzene of the formula I: ##STR3## in the presence of a base and a catalyst of Group VIII of the Periodic Table.
    Type: Grant
    Filed: May 7, 1990
    Date of Patent: February 11, 1992
    Assignee: Nissan Chemical Industries Ltd.
    Inventors: Norio Tanaka, Takuya Kakuta, Eiichi Oya, Masatoshi Baba
  • Patent number: 5086051
    Abstract: New derivatives of formula (I) in which R.sub.1 =H, halogen, alkyl, alkyloxy, CF.sub.3, NH.sub.2, alkylamino, dialkylamino, OH, CH, phenyl or phenoxy, Ar=phenyl, naphthyl, pyridyl, quinolyl, isoquinolyl, thienyl, thieno[2,3-b]thienyl or thieno[3,2-b]thienyl (these groups optionally substituted with halogen, alkyl, alkyloxy, CF.sub.3, NH.sub.2, alkylamino, dialkylamino, OH or CN), p=0, 1 or 2, andA--either Z=valency bond and R.sub.2 =HB--or Z=valency bond and R.sub.2 =pyridyl, quinuclidinyl, 3-pyrrolidinyl, 3- or 4-piperidyl (these groups optionally being substituted with alkyl, hydroxyalkyl, phenyl or phenylalkyl)C--or Z=alkylene radical (1 to 4C) and R.sub.2 =2-, 3- or 4-pyridyl, 3-quinuclidinyl, 2- or 3-pyrrolidinyl, 2-, 3- or 4-piperidyl (optionally substituted with alkyl, hydroxyalkyl, phenyl or phenylalkyl) or R.sub.2 =CON(R.sub.3)(R.sub.4) wherea) either R.sub.3 and R.sub.4 form a piperazine optionally substituted with alkyl, hydroxyalkyl, pyridyl, phenyl or phenylalkyl,b) or R.sub.
    Type: Grant
    Filed: March 14, 1990
    Date of Patent: February 4, 1992
    Assignee: Rhone-Poulenc Sante
    Inventors: Claude James, Daniel Lave, Francoise Soler