Patents Examined by M. Tuscan
  • Chimeric HIV-2 gag particles
    Patent number: 5443828
    Abstract: The chimeric proteins, and a protential vaccine and diagnostic reagent comprising gag-env chimeric protein particles are disclosed. The preparation comprises linking gag of HIV-2 to env to form the chimeric gene, inserting the obtained chimeric gene into the DNA of a baculovirus, infecting insect cells or insect host with the resulting recombinant virus, culturing it and purifying the obtained chimeric protein. The gag chimeric protein of HIV according to the present invention retains both antigenic and immunogenic properties.
    Type: Grant
    Filed: December 18, 1992
    Date of Patent: August 22, 1995
    Assignee: Korea Green Cross Corporation
    Inventors: Chil-Yong Kang, Lizhong Luo
  • Recombinant 40 KDa Dermatophagoides farinae allergen
    Patent number: 5314991
    Abstract: The present invention is directed to a recombinant mite allergen obtainable by expression of a mite-body-derived gene, a gene which codes for said allergen, a mite allergen fragment, a polypeptide having an epitope contained in said allergen, an expression vector capable of expressing the gene, a bacterium, yeast or mammalian cell transformed with said expression vector, a method for producing said allergen, and a pharmaceutical composition or a diagnostic reagent for the treatment of mite allergic diseases.
    Type: Grant
    Filed: August 22, 1991
    Date of Patent: May 24, 1994
    Assignees: Fumakilla Limited, Hiroshima University
    Inventors: Satoru Oka, Kazuhisa Ono, Seiko Shigeta, Takeshi Wada