Abstract: An endoscopic clip device for closure of a mucosal defect or transmural perforation in a gastrointestinal wall may include a sleeve and a clip disposed at least partially within and coupled to the sleeve. The clip may be configured for reversibly moving between an open configuration for positioning relative to the wall and a closed configuration for closing the defect or perforation. The clip may include a first clip arm configured for engaging the mucosal and submucosal layers of the wall and including a first needle extending to a distal end of the first clip arm and configured for advancing through the mucosal layer and into at least the submucosal layer, and a second clip arm disposed opposite the first clip arm and configured for engaging the mucosal layer. The device may be configured for advancing through an operative channel of an endoscope or overtube having a tortuous shape.

Abstract: A medical device may include an outer assembly having a first shaft, a first lumen extending through the first shaft, and an atraumatic first tip removably coupled to a distal end of the first shaft; an inner assembly configured to extend through the first lumen of the outer assembly, the inner assembly including a second shaft, a second lumen extending through the second shaft, and a second tip removably coupled to a distal end of the second shaft, the second tip being configured to pierce tissue; and a plug assembly configured to extend through the second lumen of the inner assembly, the plug assembly including a third shaft and a plug removably coupled to a distal end of the third shaft.

Abstract: A surgical fastener deployment system may include a plurality of coil fasteners having a head and coil body. In some embodiments, the head is comprised of a bioabsorbable polymer. In one embodiment, the coil body may be comprised of a shell and a core and one of the shell and the core may be comprised of one of a magnesium alloy or a bioabsorbable polymer, and the other of the shell and core is formed of the other of the magnesium alloy and the bioabsorbable polymer. The coil body may also include an internal channel which may have a support coil disposed within.

Abstract: Systems, assemblies, and methods are provided herein for fastening of one bone to another bone using one or more sutures. The features herein enable such fastening with a more accurate strength, and which can be more easily fastened in-situ.

Abstract: Surgical instrument is provided. The surgical instrument is capable of being operated manually or automatically for use in laparoscopic surgery or various surgeries and includes a locking device capable of locking and/or unlocking at least one operation.

Abstract: A depth detection apparatus, in particular in intracorneal dissection, provides a perforating tubular element suitable for being inserted into the cornea, a reciprocally moving air volume generator (14) connected to the perforating tubular element, a pressure sensor for detecting the pressure along the connection between the volumetric generator and the perforating element in the reciprocal movement of the volumetric generator, a microcontroller connected to the pressure sensor to detect pressure variations with the depth advancement into the cornea of the perforating element, a signaller connected to the microcontroller to signal that a preset pressure variation has been reached. The apparatus enables a correct position to be determined for performing intracorneal dissection.

Abstract: Embodiments described herein to a device for improving respiration comprising at least one nasal insert provided to be inserted into a nostril of a user, wherein the at least one nasal insert comprises a conical base body, a through-hole extending along the main axis of the base body, and a spiral element arranged on the inside of the base body and extending from the base of the base body to the tip of the base body.

Abstract: An ultrasonic instrument includes a body, a shaft assembly, and an end effector. The shaft assembly extends distally from the body. The shaft assembly includes an acoustic waveguide configured to acoustically couple with an ultrasonic transducer. The end effector includes an ultrasonic blade, a clamp arm and a clamp pad. The ultrasonic blade is in acoustic communication with the waveguide. The clamp arm is pivotally coupled with the shaft assembly. The clamp pad is configured to removably couple with the clamp arm while the clamp arm is pivotally coupled to the shaft assembly.

Abstract: A tool for removing non-visually, urinary tract stents placed within the urinary tract of a patient, comprising a distal end, a longitudinally-extending stem, and a handle. The distal end has a conical head with a groove for hooking a stent, stent string or similar stent configuration. The snare head may have a channel for advancing the tool through a urethra over a guide wire. The snare head has a narrow conical front end for dilating urethral strictures. The stem connects the snare head to the snare handle and is made to be flexible or bend on encountering resistance.

Abstract: A method of joining together two tissue layers includes positioning a tissue anchor over a first tissue layer. The tissue anchor includes a plate having top and bottom surfaces, an array of first pins projecting from the bottom surface of the plate that oppose the first tissue layer, and an array of second pins projecting from the top surface of the plate that face away from the first tissue layer. A second tissue layer is placed over the first tissue layer and the tissue anchor so that the second pins oppose the second tissue layer. The second tissue layer is pressed onto the tissue anchor and toward the first tissue layer so that the first pins advance into the first tissue layer and the second pins advance into the second tissue layer for joining together the first and second tissue layers. The plate has second pin apertures and the second pins are free to slide and move independently of one another within the second pin apertures.

Abstract: A surgical instrument includes a housing, an end effector, a movable handle, and a drive assembly. The movable handle includes first and second cantilever spring arms and is movable relative to the housing between a spaced-apart position and an approximated position. The first cantilever spring arm is flexed upon movement of the movable handle from the spaced-apart position towards the approximated position to bias the movable handle towards the spaced-apart position. The drive assembly is operably coupled between the movable handle and the end effector such that movement of the movable handle from the spaced-apart position towards the approximated position moves the end effector from an open position towards a clamping position for clamping tissue. The second cantilever spring arm is flexed upon application of a threshold pressure to tissue clamped by the end effector to control an amount of pressure applied to tissue clamped by the end effector.

Abstract: A nasal compressive device for preventing post-operative swelling following a rhinoplasty or other procedure performed on a user's nose or nasal cavity and prevent possible poly-beak deformities. The nasal compressive device includes nasal plugs and a nasal bridge disposed on a selectively actuated clip with a resilient spring portion. The user actuates the clip to open the nasal compressive device and then inserts the nasal plugs into their nostrils. The user then relaxes or closes the nasal compressive device which brings the nasal plugs into contact with an inner surface of their nasal cavity while also forcing the nasal bridge down on top of the user's dorsum. Once placed in the user's nose, the nasal compressive device also applies an upward force to the tip of the user's nose while also simultaneously providing a compression force over the user's dorsum, thereby reducing the amount of unwanted swelling and further shaping the nose.

Abstract: A nasal implant delivery tool includes an inner handle, an outer handle, a needle, and a push rod. The inner handle includes a loading chamber configured to receive a nasal implant. The outer handle is configured to move axially relative to the inner handle. The needle extends distally from the inner handle and has a central lumen and a distal opening. The push rod is configured to move the nasal implant from the loading chamber, through the central lumen, and out the distal opening of the needle. The push rod is coupled to the outer handle such that the push rod moves axially relative to the inner handle when the outer handle is moved axially relative to the inner handle. Also described herein are nasal implant guides and methods of using nasal implant delivery tools and nasal implant guides.

Abstract: A system for passing suture through biological tissue using a cannula, introducer or other minimally invasive means, to approximate, ligate, fixate and/or close biological tissue. The system includes a hand grip in operative communication with an elongated tubular member having a jaw mechanism disposed on the tubular member distal end. The elongated tubular member housing a deformable tubular needle therein having a curvilinear portion and an internal lumen.

Abstract: According to a general aspect, an insertion device includes an elongate member defining a lumen, a handle member movably coupled to the elongate member, a plunger member, at least a portion of the plunger member being disposed within the lumen defined by the elongate member, and an actuation member operatively coupled to the plunger member, the plunger member being configured to move from a first position within the lumen to a second location within the lumen in response to the actuation member being actuated.

Abstract: An obstruction removal device is described, having one or more engaging members which can engage portions of the clot. The one or more engaging members have a collapsed, delivery state, and an expanded, deployed state.

Abstract: Embolic material delivery devices and methods of using them are disclosed. An example embolic material delivery assembly includes an outer member having a lumen extending therein and a distal end region, an inner member disposed within the lumen of the outer member, wherein the inner member includes a first lumen extending therein. The embolic material delivery assembly also includes a first embolic material extending within the first lumen of the inner member, the embolic material having a first distal end region. The embolic material delivery assembly also includes an anchor disposed within the lumen of the outer member, the anchor having a first attachment region. Further, the first distal end region of the first embolic material is coupled to the first attachment region of the anchor.

Abstract: Methods, devices, and systems are provided herein for loading a band ligation barrel onto a surgical instrument. For example, a surgical system is provided for loading a band ligation barrel onto a surgical instrument that has a loading tube with a lumen to receive one or more band deployment cords of a band ligation barrel. The loading tube can be inserted through a first lumen of a surgical instrument. The system can also have a loading cap that receives a distal end of the loading tube, and a distal portion of the loading cap can be inserted into a distal-most opening of the band ligation barrel to secure band deployment cords therein. The system can also have a loading key that can be inserted into a second lumen of the surgical instrument, and a distal end of the loading key can engage with a proximal end of the loading tube.

Abstract: Disclosed herein is a medical leadless pacemaker delivery system adapted to engage and disengage with leadless pacemakers to allow for the repeated use of the leadless pacemaker delivery system in delivering and implanting multiple leadless pacemakers into a patient heart in a serial or repeated manner. The leadless pacemaker delivery system includes a handle, an attachment mechanism, a torque portion, and a rotation limiter. The handle includes a housing. The attachment mechanism is operably coupled to the housing and configured to actuate between a released state and an engaged state. The torque portion is operably coupled to the housing and rotatable relative to the housing to transition the attachment mechanism between the released and engaged states. The torque portion includes a shaft. The rotation limiter is in sliding engagement with the shaft between a first stop and a second stop. The rotation limiter includes a first helical thread.

Abstract: The embodiments described herein can be used in a variety of grasping, cutting, and manipulating operations. In some embodiments, an apparatus includes a first joint member, a second joint member, and a flexure. The first joint member includes a first connection portion and a contact surface. The second joint member including a second connection portion. A first end portion of the flexure is coupled to the first connection portion, and a second end portion of the flexure is coupled to the second connection portion. The flexure is configured to deform elastically when the first joint member and the second joint member move from a first configuration to a second configuration. When in the first configuration, the central portion of the flexure is spaced apart from the contact portion. When in the second configuration, the central portion of the flexure contacting the contact portion.