Abstract: Methods for monitoring a patient's level of B-type natriuretic peptide (BNP), and implantable cardiac systems capable of performing such methods, are provided. A ventricle is paced for a period of time to provoke a ventricular evoked response, and a ventricular intracardiac electrogram (IEGM) indicative of the ventricular evoked response is obtained. Based on the ventricular IEGM, there is a determination of at least one ventricular evoked response metric (e.g., ventricular evoked response peak-to-peak amplitude, ventricular evoked response area and/or ventricular evoked response maximum slope), and the patient's level of BNP is monitored based on determined ventricular evoked response metric(s). Based on the monitored level's of BNP, the patients heart failure (HF) condition and/or risks and/or occurrences of certain events (e.g., an acute HF exacerbation and/or an acute myocardial infarction) can be monitored.

Abstract: A system for measuring/monitoring the vital signs of a patient especially blood pressure, comprising a plurality of electrodes arranged at least in the waistband of an undergarment, and means for deriving measurements from the electrodes using pulse-transit times.

Abstract: A medical device detects a patient posture state and adjusts therapy based on the detected posture state. A patient posture state may be transient. To avoid adjusting therapy in response to transient posture states, a dwell time may be imposed. Using the dwell time, only those posture states that are assumed by a patient for a minimum length of time will result in therapy adjustment. To help ensure that the dwell time is set to an appropriate length of time, patient therapy adjustment data may be analyzed. Therapy adjustments made during the dwell time may indicate that the dwell time is too long. Therapy adjustments made prior to the initiation of the dwell time may also indicate that the dwell time is too long. Therapy adjustments made by the patient after expiration of the dwell time may indicate that the dwell time is too short. Based on analysis of the therapy adjustment data, the dwell time can be adjusted to a length that is appropriate for the patient and/or posture state.

Abstract: Various aspects of the present invention enable robust, reliable control functionality for effectors present on intraluminal, e.g., vascular leads, as well as other types of implantable devices. Aspects of the invention include implantable integrated circuits that have self-referencing and self-clocking signal encoding, and are capable of bidirectional communication. Also provided by the invention are effector assemblies that include the integrated circuits, as well as implantable medical devices, e.g., pulse generators that include the same, as well as systems and kits thereof and methods of using the same, e.g., in pacing applications, including cardiac resynchronization therapy (CRT) applications.

Abstract: Stimulation system, comprising an implantable stimulation device (60), at least one implantable stimulation electrode (70) and at least one initializing sensor (40), whereby the initializing sensor (40) is configured to detect in the implanted state a voluntarily controlled muscle movement, a voluntarily induced brainwave or a voluntarily generated nerve pulse of a patient during the initial phase of a swallowing process and to generate a sensor signal in response thereto either continuously or in a clocked cycle or in response to the preceding and to send this signal to the stimulation device (60), and whereby the stimulation device (60) is configured to trigger the delivery of a stimulation pulse via the stimulation electrode (70) in response to such a sensor signal of the initializing sensor (40) which is based on a voluntarily initiated swallowing process.

Abstract: A process for determining whether the location of a stimulation electrode meets a selected heart performance criteria includes providing stimulation to the heart through the electrode and obtaining an impedance measurement during stimulation delivery using an impedance sensing vector formed by electrodes that do not include the stimulation electrode. The impedance measurements are processed, either alone or in combination with an electrogram, also obtained during stimulation, to obtain a measure of hemodynamic performance.

Abstract: A heart beat sensor (10) comprises signal processing means (15) for performing frequency analysis of the output signal of a piezoelectric sensor (1) installed in a seat (2) and judging means (16) judges on the basis of the results of the frequency analysis that if the amplitude of the signal component in a first preset frequency range included in the output signal is in a preset amplitude range, the signal component includes a human body seating waveform indicating a person is seated in the seat (2).

Abstract: Tools and devices are provided for determining whether a patient is well suited to receiving an implantable cardiac stimulation device by analyzing cardiac signals captured using external or cutaneous electrodes. Some of the illustrative tools include shapes for visual comparison to printed ECG strips. Automatic devices are also disclosed which perform at least some analytical functions electronically for a user. In an example, a printed ECG strip is visually compared to a shape in order to ensure a patient is well suited to receiving a cardiac stimulation device having a particular implant location and/or cardiac signal analysis method implementation.

Abstract: An implantable medical device having an acoustic element includes a control module coupled to the acoustic element, an acoustic sensing module coupled to the control module, and a patient alert driver module coupled to the control circuit. The patient alert driver module generates a patient alert drive signal for activating the acoustic element to emit a patient alert signal. The control module includes an isolation circuit for isolating the acoustic sensing module from the acoustic element in response to the patient alert drive signal.

Abstract: A diagnostic parameter calculation method, system and program which detect symptomatically abnormal electrocardiogram data of a patient, using R-R intervals detected from electrocardiogram data collected for a patient to generate a time-series data, then generating a series of partial sets B(j)'s, each B(j) consisting of successive elements starting from the j-th element of the time-series data, and calculating characteristic quantity set (yj, xj) for each B(j), wherein yj is the mean value of all elements, and xj is the mean value of each difference of the first element from each element in the B(j), then, after splitting the (y, x)-plane into lattices, parameters u, v, w are calculated as indices for diagnosis, wherein v is the number of lattices including only one characteristic quantity set, u is the difference subtracted v from the total number of the characteristic quantity sets, and w is the maximum number of characteristic quantity sets included in a lattice.