Patents Examined by Manuel Mendez
  • Patent number: 12005207
    Abstract: Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue. In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and/or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.
    Type: Grant
    Filed: August 6, 2020
    Date of Patent: June 11, 2024
    Assignee: Neurotronic, Inc.
    Inventors: Lixiao Wang, John J. Chen, Yongxing Zhang
  • Patent number: 12005202
    Abstract: An elongated catheter includes a tissue-engaging device configured to be urged to move and contact a first surface of the first biological wall. The tissue-engaging device extends from the distal catheter section. The tissue-engaging device is configured to be urged to puncture through the first biological wall. The tissue-engaging device is also configured to be urged to contact the first biological wall without impinging the second biological wall, after the tissue-engaging device has punctured through the first biological wall.
    Type: Grant
    Filed: August 4, 2021
    Date of Patent: June 11, 2024
    Assignee: Boston Scientific Medical Device Limited
    Inventor: John Paul Urbanski
  • Patent number: 11998725
    Abstract: An auto injector for delivery of a medicament is disclosed. The auto injector comprises a housing, a syringe holder configured to receive a syringe; a first drive module adapted to move the syringe holder relatively to the housing; and a rigid needle shield remover comprising a first part adapted for separating a rigid needle shield from the syringe.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: June 4, 2024
    Assignee: Phillips-Medisize A/S
    Inventors: Bjarne Sørensen, Esben Weldingh Johansen, Jan Olesen, Jørgen Funder Rasmussen, Emil Wegger Jensen, Søren Koch Bechmann, Lucile Daul
  • Patent number: 11992656
    Abstract: A method of operating an insulin infusion device involves: operating the infusion device in an automatic mode to automatically control delivery of insulin to a user, in accordance with a first target glucose setpoint value; receiving user status data that indicates sleeping status of the user, the user status data generated by a sleep detection system; and determining, from the user status data, that the user is sleeping while the insulin infusion device is operating in the automatic mode. In response to the determining, the method transitions from the first target glucose setpoint value to a second (different) target glucose setpoint value for use during the automatic mode, the transitioning occurring without user input. The method continues to operate the infusion device in the automatic mode to automatically control delivery of insulin to the user, in accordance with the second target glucose setpoint value.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: May 28, 2024
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Lavie Golenberg, Louis J. Lintereur, Benyamin Grosman, Di Wu, Maria Diana Miller
  • Patent number: 11986417
    Abstract: The present invention relates to a method of replenishing a system for injecting a substance into the patient's body, when the system is implanted in the patient's body. The method involves replenishing the implanted reservoir by a replenishing needle penetrating the patient's skin and injecting infusion liquid comprising the substance through the replenishing needle directly or indirectly into the reservoir.
    Type: Grant
    Filed: February 11, 2021
    Date of Patent: May 21, 2024
    Inventor: Peter Forsell
  • Patent number: 11986611
    Abstract: A needle-injection catheter includes a catheter body having a distal end, a proximal end, a stiff proximal portion, a flexible distal portion, and a delivery lumen extending therethrough. In a first embodiment, a straight injection needle extends coaxially from a distal tip of the flexible portion of the catheter body, and a plurality of penetration limiting elements positioned circumferentially about a base of the straight injection needle and configured to fold radially inwardly against a shaft of the needle when constrained in a tubular lumen and to extend radially outwardly when unconstrained. In a second embodiment, a helical needle extends from the distal tip of the flexible portion of the catheter body. The helical needle has at least one helical delivery lumen connected to receive an injectable substance from the delivery lumen of the catheter body.
    Type: Grant
    Filed: September 2, 2020
    Date of Patent: May 21, 2024
    Assignee: BioCardia, Inc.
    Inventors: Wai Hsueh, Olin Jay Palmer, Scott Comiso, James B. Ross, Ken Vien, Julio Argentieri, Peter Altman
  • Patent number: 11986294
    Abstract: An aspect of an embodiment or partial embodiment of the present invention (or combinations of various embodiments in whole or in part of the present invention) comprises, but not limited thereto, a method and system (and related computer program product) for continually assessing the risk of hypoglycemia for a patient and then determining what action to take based on that risk assessment. A further embodiment results in two outputs: (1) an attenuation factor to be applied to the insulin rate command sent to the pump (either via conventional therapy or via open or closed loop control) and/or (2) a red/yellow/green light hypoglycemia alarm providing to the patient an indication of the risk of hypoglycemia. The two outputs of the CPHS can be used in combination or individually.
    Type: Grant
    Filed: May 30, 2023
    Date of Patent: May 21, 2024
    Assignee: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Boris P. Kovatchev, Marc D. Breton, Stephen D. Patek
  • Patent number: 11986632
    Abstract: A system and method for operating an analgesia administration system is disclosed. A control device is associated with a drug delivery device and configured to receive a first user input including at least a portion of a fingerprint of a patient, together with a second user input corresponding to a request to administer medication. The portion of the fingerprint is compared with previously-stored fingerprints to determine an identity of the patient and, in response to receiving the second user input and determining that the patient is an authorized user, one or more sensors are used to obtain one or more signals indicative of a state of the patient. If the state of the patient satisfies a set of medication delivery criteria, the drug delivery device is caused to administer a predefined amount of medication to the patient.
    Type: Grant
    Filed: May 13, 2021
    Date of Patent: May 21, 2024
    Assignee: CareFusion 303, Inc.
    Inventors: Brendan John Burgess, Edward Stephen Ferner, Beth A. Schneider, Shannon John Johnson, Daniel M. Abal
  • Patent number: 11986625
    Abstract: In some aspects, systems, devices, and techniques for programming a medical fluid delivery device are described. In one example, the disclosure relates to a system including a medical fluid delivery device configured to deliver a therapeutic agent to a patient, and a processor. The processor may be configured to receive a proposed therapy dosing program that defines a fluid therapy for delivery to a patient via a medical fluid delivery device for a first period of time, determine a total dosage over a second period of time, where the second period of time at least partially overlaps the first period of time, and compare the total dosage over the second period of time to a reference dosage.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: May 21, 2024
    Assignee: Medtronic, Inc.
    Inventor: Touby A. Drew
  • Patent number: 11980728
    Abstract: A radiopaque balloon with a composite wall having a radiopaque adhesive affixing inner and outer layers of the balloon. The radiopaque adhesive provides a radiographic image of the balloon wall with or without the use of radiopaque contract media to inflate the balloon. A radiographically fainter image is provided as the balloon is inflated with well-defined edges of a balloon image, and the total radiopacity of the balloon does not change as the balloon is inflated. Also, a method of imaging a balloon wall and a method of imaging a radiopaque adhesive between two layers of a balloon wall are provided.
    Type: Grant
    Filed: September 22, 2020
    Date of Patent: May 14, 2024
    Assignee: C.R. Bard, Inc.
    Inventor: Richard K. Elton
  • Patent number: 11969579
    Abstract: A method of insulin delivery, the method may include obtaining one or more blood glucose readings of a user, and, based on the blood glucose readings, generating a set of insulin delivery actions that may include delivery of a baseline basal rate or predefined variations of the baseline basal rate. The method may also include monitoring previous insulin delivery actions to the user to determine whether the previous insulin delivery actions include insulin beyond a threshold amount, where the previous insulin delivery actions may include delivery of the baseline basal rate or predefined variations of the baseline basal rate, and, based on the previous insulin delivery actions including insulin beyond the threshold amount, adjusting the set of insulin delivery actions.
    Type: Grant
    Filed: June 11, 2021
    Date of Patent: April 30, 2024
    Assignee: Insulet Corporation
    Inventors: Bryan Mazlish, Lane Desborough
  • Patent number: 11957875
    Abstract: Disclosed are a device, system, methods and computer-readable medium products that provide an updated insulin-to-carbohydrate ratio and an updated total daily insulin. The described processes may be used for periodic updating of the insulin-to-carbohydrate ratio and the total daily insulin. The insulin-to-carbohydrate ratio and/or the total may be used in the calculation of new doses of insulin that a drug delivery device may be commanded to deliver to a user.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: April 16, 2024
    Assignee: INSULET CORPORATION
    Inventors: Yibin Zheng, Joon Bok Lee, Steven Cardinali, Jason O'Connor, Eric Benjamin, Ian McLaughlin, David Nazzaro, Ashutosh Zade
  • Patent number: 11957876
    Abstract: An automated blood glucose control system is configured to generate a backup therapy protocol comprising insulin therapy instructions derived from autonomously determined doses of insulin. The system generates a dose control signal using a control algorithm configured to autonomously determine doses of insulin to be infused into a subject for the purpose of controlling blood glucose of the subject based at least in part on a glucose level signal received from a glucose sensor. The system can track insulin therapy administered to the subject over a tracking period, including storing an indication of the autonomously determined doses of insulin delivered to the subject as basal insulin, as correction boluses of insulin, or as mealtime boluses of insulin. The system can generate a backup injection therapy protocol or a backup pump therapy protocol with insulin therapy instructions based at least in part on the insulin therapy administered to the subject over the tracking period.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: April 16, 2024
    Assignee: BETA BIONICS, INC.
    Inventors: Edward B. Raskin, David Chi-Wai Lim, Michael J. Rosinko, Firas H. El-Khatib, Edward R. Damiano
  • Patent number: 11957874
    Abstract: Some embodiments an infusion pump system can be configured to modify alarm limit parameters as the user's insulin load increases or decreases. Moreover, in particular embodiments, the infusion pump system can be configured to provide a “missed bolus” or “missed meal” alarm in response to the user's blood glucose characteristics, the user's insulin load information, or the like.
    Type: Grant
    Filed: July 14, 2020
    Date of Patent: April 16, 2024
    Assignee: INSULET CORPORATION
    Inventor: Mark C. Estes
  • Patent number: 11951246
    Abstract: A method of coaching a patient to use an inhaler for medication delivery is provided. The method includes obtaining, via a sensor, respiratory behavior data of the patient; receiving, at a computing device, the respiratory behavior data; performing a respiratory pattern analysis algorithm on the respiratory behavior data to determine a desired interval of inhaler actuation for medication delivery; communicating a cue signal to actuate the inhaler to achieve the desired interval; obtaining, via the sensor, inhaler actuation data based on the actuation of the inhaler; receiving, at the computing device, the inhaler actuation data; performing an actuation analysis algorithm on the inhaler actuation data to assess the efficacy of the actuation; and adjusting the cue signal to actuate the inhaler to improve the efficacy of a future actuation.
    Type: Grant
    Filed: September 27, 2023
    Date of Patent: April 9, 2024
    Assignee: Yale University
    Inventor: Peter Kahn
  • Patent number: 11951262
    Abstract: Catheters, sheaths, or other tubular devices are provided that include a proximal end, a distal end sized for introduction into a patient's body, and a steerable distal portion. The tubular device includes a primary lumen extending between the proximal and distal ends; an auxiliary lumen adjacent the primary lumen; and one or more reinforcement members including windings extending helically along at least the distal portion, at least some of the windings passing between the primary and steering element lumens and at least some of the windings surrounding both the primary and steering element lumens. In one embodiment, a steering element is slidably disposed within the auxiliary lumen. Apparatus and methods for making such tubular devices are also provided.
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: April 9, 2024
    Assignee: CLPH, LLC
    Inventors: Stephen A. Leeflang, Christian S. Eversull
  • Patent number: 11944771
    Abstract: The invention claims a new type of handheld medical device is meant to help the medical community by enabling them to treat patients remotely. This solves the problem of patient suffering or death due to lack of access to a medical professional or long wait times by enabling a patient-centred response to diseases, such as COVID-19. The device is hand-held, with incorporated germicidal UVC lights, an internal application tip and the delivery mechanism focuses on the mucous membrane. The top chamber connects to a removable container which can be used with the prescribed treatment/therapy, vaccine, or viral testing fluid/reagent, as needed. The versatility, non-invasive nature and germicidal properties constitute distinct improvements over other similar medical devices. This device also promotes the development of non-invasive inoculation and drug delivery systems via the mucous membrane.
    Type: Grant
    Filed: March 9, 2022
    Date of Patent: April 2, 2024
    Inventor: Andrada Bucataru
  • Patent number: 11944400
    Abstract: Robotic Angioplasty and Endoluminar Surgery System to separate patient and operator by remotely moving guides and catheters during operations, composed of three or more elements, of which at least one disposable (nose), available in different versions, like for independent advancements and retractions of a balloon catheter (or stent) and relative guide and to their common axial rotation, or for moving a guide with a moving core or a catheter. The nose should be inserted into a non-sterile Slave placed near the patient, covered with sterile drapes, and with a combination of toothed wheels it translates all into three rotations controlled by three independent motors, possibly measuring the torque applied by the motors. By replacing the three angular gauges to the motors, a Master is obtained, controlled by a doctor by moving non-sterile tubes.
    Type: Grant
    Filed: October 26, 2018
    Date of Patent: April 2, 2024
    Inventors: Guido Danieli, Ciro Indolfi, Salvatore De Rosa, Domenico Battaglia, Giovanni De Gaetano, Gionata Fragomeni, Pasquale Francesco Greco, Gabriele Larocca, Michele Perrelli
  • Patent number: 11944178
    Abstract: A system and method for dermal spraying includes a portable, hand-held dermal application device with disposable formulation capsules that spray a formulation unto the skin and a data transmission unit operatively connecting the dermal spray device to a mobile device. The mobile device communicates with a remote server and transmits anonymized data about the user's skin conditions and treatment history. The anonymized data may be labelled and classified by a dermatologist, and stored on a secure cloud server. The anonymized data is used to train models for serum and treatment plan recommenders.
    Type: Grant
    Filed: April 7, 2021
    Date of Patent: April 2, 2024
    Assignee: Kozhya LLC SP Z.O.O.
    Inventors: Yoanna Gouchtchina, Enrique Gallar
  • Patent number: 11944785
    Abstract: Devices, systems, and techniques for therapy delivery and healthcare management is described. In one example, a system comprises a delivery device configured to execute therapy information comprising a treatment schedule specifying one or more treatments over a time period, wherein for each of the one or more treatments, the therapy information comprises a treatment type and a treatment amount; and processing circuitry configured to: determine a modification to the therapy information based on a recommendation of a digital twin, wherein the digital twin determines an estimated glucose level expected to be within a healthy range if the delivery device executes the modification to therapy information; and in response to physician review of the modification to the therapy information, output, to a healthcare provider system for the patient, data indicating completion of a healthcare service corresponding to the physician review.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: April 2, 2024
    Assignee: Medtronic MiniMed, Inc.
    Inventors: Louis J. Lintereur, Catherine Tan Fogel, Patrick E. Weydt, Benyamin Grosman, Mahta Sadeghzadeh