Abstract: A medical system includes a probe, an electro-optical measurement unit, and a processor. The probe is configured for insertion into a blood vessel of a brain, and includes two optical fibers, which include each an optical diffuser at distal ends thereof. One fiber is configured to guide an optical signal to a location along the blood vessel and to diffuse the optical signal so as to interact with a brain clot in the blood vessel. The other fiber is configured to collect the diffused optical signal that interacted with the brain clot at another location along the blood vessel. The electro-optical measurement unit is configured to transmit the optical signal to one optical fiber, and to receive and measure the diffused optical signal from the other optical fiber. The processor is configured to identify a composition of the brain clot by analyzing the measured diffused optical signal.

Abstract: An intraluminal imaging system is provided. The intraluminal imaging system includes a patient interface module (PIM) in communication with an intraluminal device comprising an ultrasound imaging component and positioned within a body lumen of a patient, a wireless router via an signal link, and a computing device in wireless communication with the wireless router, wherein the PIM comprises a processing component configured to receive an ultrasound echo signal from the ultrasound imaging component; and determine image data based on at least the ultrasound echo signal; and a power and communication component configured to receive power from the signal link; and transmit, to the computing device via the signal link and the wireless router, the image data.

Abstract: Systems and methods for applying ultrasound sonication to temporarily disrupt a patient's blood-brain barrier (BBB) include storing threshold values of an acoustic response level, an acoustic response dose and a tissue response dose associated with a target BBB region and its surrounding regions based on anatomical characteristics thereof; causing the ultrasound transducer to transmit one or more pulses/waves; measuring the acoustic response level, the acoustic response dose, and/or the tissue response dose associated with the target BBB region and/or its surrounding regions; comparing the measurement with a corresponding stored threshold value; and operating the transducer based at least in part on the comparison.

Abstract: An ultrasound imaging system for needle insertion guidance uses a curved array transducer to scan an image field with unsteered beams as a needle is inserted into the image field. Due to differences in the angle of incidence between the radially directed beams and the needle, echoes will return most strongly from only a section of the needle. This section is identified in an image, and the angle of incidence producing the strongest returns is identified. Beams with this optimal angle of incidence are then steered in parallel from the curved array transducer to produce the best needle image. The steep steering angles of some of the steered beams can give rise to side lobe clutter artifacts, which can be identified and removed from the image data using dual apodization processing of the image data.

Abstract: An image-based approach of calibrating an ultrasound-probe is described, wherein at least two ultrasound-images which cross each other are acquired with a tracked ultrasound probe, and wherein the intersection areas of these images, which have been calculated on the basis of the tracked spatial position of the ultrasound probe are checked for similar image content. The grade of similarity gives an indication as to how well the ultrasound probe is calibrated.

Abstract: Techniques are described for determining cognitive impairment, an example of which includes accessing a set of epochs of magnetoencephalography (MEG) data of responses of a brain of a test patient to a plurality of auditory stimulus events; processing the set of epochs to identify parameter values one or more of which is based on information from the individual epochs without averaging or otherwise collapsing the epoch data. The parameter values are input into a model that is trained based on the parameters to determine whether the test patient is cognitively impaired.

Abstract: Systems and methods are disclosed herein for processing ultrasound images to identify objects for diagnostic and/or interventional use. For instance, an ultrasound image of an anatomical structure may be received from a computing device of an ultrasound imaging system. The ultrasound image may be input to a machine learning model that is trained to identify a plurality of objects in ultrasound images of the anatomical structure. The plurality of objects may include anatomical features, disruptive features, and/or instruments. A prediction of one or more objects from the plurality of objects identified in the ultrasound image may be received as output of the machine learning model. An indication of the prediction may be provided to the computing device for display on a display of the ultrasound imaging system.

Abstract: A vascular occlusion treatment system includes an ultrasound imaging system having an imaging control circuit communicatively coupled to an ultrasound imaging probe and to a display screen, and an ultrasonic vibration system having an ultrasonic generator operatively coupled to a medical ultrasonic object, such as an ultrasonic catheter. The ultrasonic catheter has a corewire with a distal tip. The ultrasonic generator has a generator control circuit that alternatingly switches between an ultrasonic work frequency and a tracking frequency. The generator control circuit sends a notification to the imaging control circuit when the generator control circuit has switched from the ultrasonic work frequency to the tracking frequency. The imaging control circuit responds by initiating a search in an ultrasound imaging space to locate the distal tip that is vibrating at the tracking frequency, and indicating a location of the distal tip in the ultrasound image displayed on the display screen.

Abstract: A system for guiding a medical intervention is disclosed. The system employs a device guide that operates on the surface of a sphere that is centered on a selected target.

Abstract: Disclosed in the present application is an ultrasound contrast enhanced imaging method, comprising: transmitting unfocused waves in a plurality of angles to a target region containing microbubbles; receiving echo signals of the unfocused waves; selecting echo signals corresponding to at least some of the plurality of angles from the echo signals; generating contrast enhanced image according to the selected echo signals, performing color-coding on the contrast enhanced image, and displaying same. Also disclosed in the present application is an ultrasound imaging system.

Abstract: A system for spatially mapping neurons in brain tissue is disclosed which includes a source of light configured to be shone on a subject at a first wavelength causing emission of light at a second wavelength from generating calcium when one or more neurons are firing, an optical filter configured to allow passage of light having the second wavelength, an image capture device configured to capture images of the brain tissue at the second wavelength, and a processor with software configured to establish a spatial model for localizing one or more neurons where captured images are used to iteratively adjust parameters of the model to thereby minimize error between generated and captured images.

Abstract: An ultrasound imaging system including an image processor configured to receive input data for capturing ultrasound images of a region of interest. The ultrasound images are taken along a first plane; and the input data further includes an indication that a needle will be inserted into the region of interest. The system can capture a plurality of ultrasound images of the region of interest along the first plane. The system can determine one or more high-confidence areas of the region of interest where the needle will intersect the first plane. Each high-confidence area is based on a probability that the needle will intersect the first plane at any portion of the high-confidence area; and display one or more on-screen markers corresponding to the one or more high-confidence areas in conjunction with the plurality of ultrasound images on the display.

Abstract: Provided is an ultrasound system including an ultrasound probe and an image display device. The ultrasound probe includes: a transducer array, a transmitting and receiving unit that generates a sound ray signal on the basis of a reception signal from the transducer array; an image information data generation unit that generates image information data from the sound ray signal; and a probe-side wireless communication unit that transmits the image information data to the image display device. The image display device includes: an operating state acquisition unit that acquires an operating state of the image display device; and a display-device-side wireless communication unit that transmits the operating state to the ultrasound probe.

Abstract: A vascular occlusion treatment system includes an ultrasound imaging system having an imaging control circuit communicatively coupled to an ultrasound imaging probe and to a display screen, and an ultrasonic vibration system having an ultrasonic generator operatively coupled to a medical ultrasonic object, such as an ultrasonic catheter. The ultrasonic catheter has a corewire with a distal tip. The ultrasonic generator has a generator control circuit that alternatingly switches between an ultrasonic work frequency and a tracking frequency. The generator control circuit sends a notification to the imaging control circuit when the generator control circuit has switched from the ultrasonic work frequency to the tracking frequency. The imaging control circuit responds by initiating a search in an ultrasound imaging space to locate the distal tip that is vibrating at the tracking frequency, and indicating a location of the distal tip in the ultrasound image displayed on the display screen.

Abstract: A magnetic resonance imaging system including a memory configured to store machine executable instructions, pulse sequence commands, and a first machine learning model including a first deep learning network. The pulse sequence commands are configured for controlling the magnetic resonance imaging system to acquire a set of magnetic resonance imaging data.

Abstract: A method for identifying a source of florescence is disclosed which includes shining light on a subject at a first wavelength, causing emission of light at a second wavelength from the source of fluorescence, filtering out light at the first wavelength, capturing at least one 2 dimensional (2D) image of a subject having a plurality of pixels at the second wavelength, and establishing information about approximate location of a source of florescence within a tissue of the subject, selectively generating a 3D geometric model where the model is adapted to provide a model representation of the at least one 2D captured image, comparing the modeled at least one 2D captured image to the captured at least one 2D image and iteratively adjusting the model to minimize the difference, and outputting location and geometric configuration of the source of fluorescence within the tissue within the region of interest.

Abstract: A navigation method for a medical operation and implemented by a robotic system is provided. The method includes the steps of: receiving, at a processor of the robotic system, at least one set of navigation data; receiving or generating at least one three-dimensional model of the virtual object in the navigation data; calculating the navigation data to generate a virtual environment and at least one navigation instruction; and presenting, at a user interface associated with the robotic system, the virtual environment and/or the navigation instruction to a user of the robotic system for the user to refer to during the medical operation.

Abstract: The power supply in ultrasound imaging includes a switched capacitance. The capacitance is switched on to provide power during generation of pushing pulses for elasticity imaging and is switched off during other modes of imaging.

Abstract: Photoacoustic targeting systems for intracellular recording. In one embodiment, the photoacoustic targeting system includes a light source, a micropipette electrode, an acoustic transducer, and a controller. The light source is configured to emit pulsed light. The micropipette electrode is configured to deliver the pulsed light to a target cell. The acoustic transducer is configured to receive photoacoustic signals generated due to optical absorption of light energy by the target cell. The controller is configured to determine a position of the micropipette electrode relative to the target cell based on the photoacoustic signals.

Abstract: An ultrasound diagnosis apparatus including: an ultrasound probe; a processor configured to perform transmission of ultrasound beam from the ultrasound probe to a subject to acquire an ultrasound image; a camera configured to acquire a digital image of a state of the ultrasound probe being in contact with the subject; a touch panel including a display screen displaying the ultrasound image and the digital image; an interface to receive instruction to acquire the ultrasound image and/or the digital image from a user; and a memory configured to store the ultrasound image and the digital image, wherein the processor is further configured to: exclusively control between the acquisition of the ultrasound image and the acquisition of the digital image according to instruction received by the interface; and save the ultrasound image and the digital image of the same inspection in the memory in association with each other.