Abstract: The present invention is directed to methods of using pro-NAD agents capable of enhancing the dermal and epidermal skin cell NAD content. These pro-NAD agents may be administered topically, orally, or parenterally to enhance DNA repair and other protective responses to DNA damage. The invention further relates to pharmaceutical compositions comprising pro-NAD agents that effectively elevate intracellular NAD content. Finally, the invention relates to the method of using the pro-NAD agents to treat disorders such as sunburn and other skin deterioration that results from DNA damage in skin cells.

Abstract: The invention relates to a perfume composition which, at the same time, has a tanning effect or both a sun-block and tanning effect. According to the invention, the perfume composition having a tanning effect or both a sun-block and tanning effect is comprised of a clear hydroalcoholic solution. Said solution contains an alcohol-soluble, organic sunscreen filter in a proportion of 0.05 to 12 wt. %; dihydroxyacetone in a proportion of 0.5 to 10 wt. %; one or more monovalent alcohols with 3 to 5 carbon atoms in a proportion of 30 to 85 wt. %; one or more polyvalent alcohols with 3 to 5 carbon atoms in a proportion of 0.5 to 15 wt %; perfume oil in a proportion of 1 to 20 wt. %; and water in a proportion of 3 to 67.95 wt. %, hereby the proportions refer each time to the total composition.

Abstract: Methods and compositions are disclosed utilizing optically pure R-(-)-casodex for the treatment of androgen-dependent prostate cancer, while substantially reducing the concomitant liability of adverse effects associated with the racemic mixture of casodex. R-(-)-casodex is an antiandrogen and is therefore useful in the treatment of other conditions supported by androgen or caused by elevated androgen levels. Such conditions include benign prostatic hypertrophy or hyperplasia, acne and hirsutism.