Patents Examined by Marjan Fardanesh
  • Patent number: 11406295
    Abstract: Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: August 9, 2022
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Andrea Varsavsky, Xiaolong Li, Mike C. Liu, Yuxiang Zhong, Ning Yang
  • Patent number: 11406321
    Abstract: A sweat sensing device includes a flexible body having a first, outwardly facing surface and a second, skin facing surface and a sweat channel formed in the body, the sweat channel having a first end defining a fluid inlet and a second end. A biochemical assay well formed in the sweat channel and an assay material is disposed in the biochemical assay well, the assay material positioned to react with sweat traveling through the sweat channel and to provide one of a visual indicator and an indicator detectable by a camera and connected processor of the flow of the sweat in the sweat channel.
    Type: Grant
    Filed: July 24, 2018
    Date of Patent: August 9, 2022
    Assignee: Epicore Biosystems, Inc.
    Inventors: Jeffrey B. Model, Roozbeh Ghaffari, Alexander J. Aranyosi, Stephen P. Lee, Milan S. Raj
  • Patent number: 11399749
    Abstract: Provided is an optical sensor, including a light source configured to emit light; a photodetector array comprising a plurality of photodetectors positioned at different distances from the light source, each photodetector being configured to detect an optical signal returning from an object irradiated by the light emitted by the light source, and to measure a light intensity of the detected optical signal; and a processor configured to determine a correlation coefficient between variables based on the measured light intensity, and to determine a quality of the optical signal based on the determined correlation coefficient, an optical characteristic of the object being determined by selectively using the optical signal of which the quality is an acceptable level or higher.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: August 2, 2022
    Assignee: SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Joon Hyung Lee, Kak Namkoong, Jung Yong Nam, Yeol Ho Lee, Ki Young Chang, Won Jong Jung
  • Patent number: 11395630
    Abstract: An ocular device is disclosed along with methods for the employment thereof. In one aspect, a device for placement into a lacrimal punctum or conjunctival sac of a person includes one or more sensor materials responsive to one or more components of the chemical composition of the person's tears. Each sensor material is configured to present a tear-based color from a plurality of tear-based colors indicative of a medical condition of the person. In some embodiments, phenylboronic acid could be employed as a sensor material(s). In some embodiments, material(s) emitting radiation when excited by other radiation could be employed as a sensor material. In another aspect, methods for employing the ocular device are disclosed.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: July 26, 2022
    Assignee: TearDX LLC
    Inventors: Eugene Orloff, Paul V. Braun, Eleonora Orloff, Yang Fei
  • Patent number: 11382544
    Abstract: Described here are meters and methods for sampling, transporting, and/or analyzing a fluid sample. The meters may include a meter housing and a cartridge. In some instances, the meter may include a tower which may engage one or more portions of a cartridge. The meter housing may include an imaging system, which may or may not be included in the tower. The cartridge may include one or more sampling arrangements, which may be configured to collect a fluid sample from a sampling site. A sampling arrangement may include a skin-penetration member, a hub, and a quantification member.
    Type: Grant
    Filed: December 10, 2018
    Date of Patent: July 12, 2022
    Assignee: Intuity Medical, Inc.
    Inventors: Paul D. Reynolds, Raul Escutia, John F. Larkin, Charles Hu, Michael F. Tomasco, Daniel R. Bloom, Joseph A. Vivolo, Richard M. Wiard
  • Patent number: 11382538
    Abstract: Methods and systems for sensor calibration and sensor glucose (SG) fusion are used advantageously to improve the accuracy and reliability of orthogonally redundant glucose sensor devices, which may include optical and electrochemical glucose sensors. Calibration for both sensors may be achieved via fixed-offset and/or dynamic regression methodologies, depending, e.g., on sensor stability and Isig-Ratio pair correlation. For SG fusion, respective integrity checks may be performed for SG values from the optical and electrochemical sensors, and the SG values calibrated if the integrity checks are passed. Integrity checks may include checking for sensitivity loss, noise, and drift. If the integrity checks are failed, in-line sensor mapping between the electrochemical and optical sensors may be performed prior to calibration.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: July 12, 2022
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Andrea Varsavsky, Xiaolong Li, Mike C. Liu, Yuxiang Zhong, Ning Yang
  • Patent number: 11375961
    Abstract: A vehicle includes a control system for controlling one or more operations of the vehicle. A touchpoint integrated in the vehicle is configured to receive PPG signals reflected from skin of an occupant, wherein the PPG signals are at a plurality of wavelengths. A processing circuit is configured to determine a signal quality of at least one of the PPG signals and generate one or more of: a visible feedback, an audible feedback or a tactile feedback in response the signal quality of the at least one PPG signal. The PPG signals to obtain health information of a user and generate a health message to the control system of the vehicle in response to the health information, wherein the control system controls one or more operations of the vehicle in response to the health message.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: July 5, 2022
    Assignee: TRILINEAR BIOVENTURES, LLC
    Inventor: Robert Steven Newberry
  • Patent number: 11375927
    Abstract: An analyte monitoring system may include an analyte sensor and a transceiver. The analyte sensor may include: a sensor housing, an analyte indicator on at least a portion of the sensor housing, a protective material on at least a portion of the analyte indicator, and a light source in the sensor housing and configured to emit excitation light to analyte indicator. The transceiver may be configured to receive the sensor measurements conveyed by the analyte sensor, infer information about a condition of the environment surrounding the analyte sensor, and calculate an analyte level using at least one or more of the sensor measurements and the inferred information about the condition of the environment surrounding the sensor. The protective material may have a thickness that is thin enough to allow at least some of the excitation light to pass through the protective material and into the environment surrounding the analyte sensor.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: July 5, 2022
    Assignee: Senseonics, Incorporated
    Inventors: Andrew DeHennis, Xiaoxiao Chen
  • Patent number: 11375910
    Abstract: A pulse sensing device including main body with at least a pair of sensors, a power source, a power connector, at least one light source electrically coupled to the at least a pair of sensors and a divider configured to separate the power source from the power connector, a casing surrounding the main body, and, an adhesive layer located on a surface of the casing.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: July 5, 2022
    Inventor: Joseph Cuccinello
  • Patent number: 11375958
    Abstract: System, method, and device is presented for generating and processing tissue-monitoring signals. An emitting driver is operable to control, upon receipt of at least one emitted signal, an optical emitter to emit at least one emitted signal. A processor is coupled to the at least one optical emitter and operable to execute instructions to generate the at least one emitted signal. At least one photodetector is operable to detect one or more photons transmitted through tissue and to convert the detected photons into a detected signal. A hardware processing sequence is coupled to the photodetector and processor. The hardware processing sequence is operable to filter and condition the detected signal. The processor is operable to execute instructions to demodulate the at least one emitted signal and the detected signal.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: July 5, 2022
    Assignee: HAPPY HEALTH INC.
    Inventors: Paulo E. Xavier Da Silveira, David E. Clift-Reaves, CJ Picklesimer, Nithin O. Rajan
  • Patent number: 11369294
    Abstract: A measurement value calculation section calculates the actual measurement value of the hemoglobin concentration of an object to be observed and the actual measurement value of an oxygen saturation thereof on the basis of a plurality of first spectral images. A relative value calculation section calculates the relative value of the hemoglobin concentration and the relative value of the oxygen saturation on the basis of the actual measurement value and the reference value of the hemoglobin concentration and the actual measurement value and the reference value of the oxygen saturation. An image generation section generates a relative value image obtained from the imaging of the relative value of the hemoglobin concentration and/or the relative value of the oxygen saturation, and displays the relative value image on a display unit.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: June 28, 2022
    Assignee: FUJIFILM Corporation
    Inventor: Takaaki Saito
  • Patent number: 11369314
    Abstract: Devices, kits, and methods for (a) determining the presence and/or concentration of at least one analyte(s) of interest present in a patient's fluid sample and devices and methods of calibration related thereto, and (b) preventing, mitigating, and/or eliminating biofouling of an indwelling, wearable biosensor are disclosed and/or claimed herein.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: June 28, 2022
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventor: David Ledden
  • Patent number: 11372176
    Abstract: An implantable optical sensor comprises a photonic integrated circuit comprising a substrate 2 and an optical microstructure 3 integrated with the substrate 2. The optical microstructure is positioned to form an exposed optical interaction area 4 on a part of a surface 5 of the substrate 2. A cover cap 6 is sealed onto a part of the substrate 2 adjacent to the optical interaction area 4 and by wafer-to-wafer bonding technology or another wafer-level hermetic packaging technique. At least one active component 8 is positioned in a sealed cavity 9 which is formed between the surface 5 and the cover cap 6. The substrate 2 comprises at least one optical feedthrough 10, which is an embedded waveguide extending from the sealed cavity 9 to the optical interaction area 4.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: June 28, 2022
    Assignee: Indigo Diabetes N.V.
    Inventors: Koenraad Van Schuylenbergh, Danaë Delbeke, Paolo Cardile
  • Patent number: 11363960
    Abstract: A patient monitor capable of measuring microcirculation at a tissue site includes a light source, a beam splitter, a photodetector and a patient monitor. Light emitted from the light source is split into a reference arm and a sample arm. The light in the sample arm is directed at a tissue site, such as an eyelid. The reflected light from the tissue site is interfered with the light from the reference arm. The photodetector measures the interference of the light from both the sample arm and the reference arm. The patient monitor uses the measurements from the photodetector to calculate the oxygen saturation at the tissue site and monitor the microcirculation at the tissue site.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: June 21, 2022
    Assignee: Masimo Corporation
    Inventor: Massi Joe E. Kiani
  • Patent number: 11357430
    Abstract: Biomonitoring systems and methods of loading and releasing the same are disclosed herein. In one embodiment, a biomonitoring system includes a wearable sensor patch and an applicator. The sensor patch has a filament and an electronics subsystem. The sensor patch is configured to detect a parameter of an analyte in fluid of a user when it is adhered to the user's skin and the filament extends into the user's tissue. The applicator includes first and second applicator portions and a spring positioned within an interior of the second application portion between the first and second applicator portions. When the applicator transitions from a loaded mode to a released mode, the spring transitions from a first state of compression to a second, lower state of compression and accelerates the first applicator portion and the wearable sensor patch toward the user's skin such that the filament extends into the user's tissue.
    Type: Grant
    Filed: August 23, 2021
    Date of Patent: June 14, 2022
    Assignee: One Drop Biosensor Technologies, LLC
    Inventors: Ashwin Pushpala, Dominic Pitera, Matthew Chapman, Michael Gifford
  • Patent number: 11330997
    Abstract: A method of detection of an analyte includes implementing a scan routine using a detector array that is electrically connected to a transmit circuit and electrically connected to a receive circuit, the detector array having at least three detector elements. In a first scan, a first combination of the detector elements is used to transmit a first transmit signal that is in a radio or microwave frequency or visible range of the electromagnetic spectrum into a target containing at least one analyte of interest and used to detect a response resulting from transmission of the first transmit signal into the target. In a second scan, a second combination of the detector elements, different from the first combination, is used to transmit a second transmit signal that is in a radio or microwave frequency or visible range of the electromagnetic spectrum into the target and is used to detect a response resulting from transmission of the second transmit signal into the target.
    Type: Grant
    Filed: February 1, 2021
    Date of Patent: May 17, 2022
    Assignee: KNOW LABS, INC.
    Inventor: Phillip Bosua
  • Patent number: 11331009
    Abstract: Presented herein are devices for collecting and/or channeling a biofluid (e.g., sweat, tears, saliva) and detecting and/or quantifying one or more biomarkers in the biofluid. The one or more biomarkers may include, for example, ions, salts thereof, hormones and/or steroids, proteins, metabolites and organic compounds. In certain embodiments, the devices described herein include a specially designed interface and a zero-energy micro pump that allow the device to be comfortably affixed directly to the skin of a user while biofluid is efficiently and non-invasively collected from the skin of the user. In certain embodiments, the biofluid collection and sensing device is housed on or in another wearable device, such as a wrist band or a smart watch. In certain embodiments, the devices described herein are disposable (e.g., after a certain period of use and/or wear the device can be disposed and replaced with a low-cost replacement).
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: May 17, 2022
    Assignees: Xsensio SA, ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Mihai Adrian Ionescu, Johan Frédéric Longo, Fabien Patrick Wildhaber, Hoël Maxime Guérin, Francesco Bellando, Erick García Cordero
  • Patent number: 11330962
    Abstract: An endoscope system has an oxygen saturation calculation unit that calculates the oxygen saturation of an observation object, and includes an image acquisition unit that acquires a preliminarily captured image that is an image of the observation object, a correction unit that corrects an LUT that the oxygen saturation calculation unit uses for the calculation of the oxygen saturation, using the preliminarily captured image, a determination unit that determines a success or failure of the correction, and a warning unit that performs warning in a case where a determination result obtained by the determination unit is a failure.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: May 17, 2022
    Assignee: FUJIFILM Corporation
    Inventor: Takaaki Saito
  • Patent number: 11331046
    Abstract: A pulse oximeter includes one or more processor and one or more memory storing instructions. When the instructions are executed by the one or more processor, the one or more processor causes the pulse oximeter to acquire a first signal corresponding to an intensity of first light having a first wavelength and a second signal corresponding to an intensity of second light having a second wavelength, set a presumptive value of an arterial oxygen saturation, acquire an arterial blood component signal and a venous blood component signal corresponding to the presumptive value from the first signal and the second signal, acquire an index value corresponding to a phase difference between the arterial blood component signal and the venous blood component signal, and calculate the arterial oxygen saturation based on a variation of the index value associated with a change of the presumptive value.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: May 17, 2022
    Assignee: Nihon Kohden Corporation
    Inventor: Tetsuo Suzuki
  • Patent number: 11330987
    Abstract: An implantable vital sign sensor including a housing including a first portion, the first portion defining a first open end, a second open end opposite the first end, and a lumen there through, the first portion being sized to be implanted substantially entirely within the blood vessel wall of the patient. A sensor module configured to measure a blood vessel blood pressure waveform is included, the sensor module having a proximal portion and a distal portion, the distal portion being insertable within the lumen and the proximal portion extending outward from the first open end.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: May 17, 2022
    Assignees: Thomas Jefferson University, RTM Vital Signs LLC
    Inventors: Apurva Jain, Jeffrey I. Joseph, Nance Dicciani, Denise Devine, David Demmer