Abstract: A system for detecting unsafe equipment operation conditions using physiological sensors includes a plurality of wearable physiological sensors, each physiological sensor of the plurality of wearable physiological sensors configured to detect at least a physiological parameter of an operator of an item of equipment, and a processor in communication with the at least a physiological sensor and designed and configured to determine an equipment operation parametric model, wherein the equipment operation parametric rule relates physiological parameter sets to equipment operation requirements, detect using the equipment operation parametric model and the plurality of physiological parameters, a violation of an equipment operation requirement, and generate a violation response action in response to detecting the violation.

Abstract: An improved analyte monitoring system having a sensor and a transceiver with improved communication and/or user interface capabilities. The transceiver may communicate with and power the sensor. The transceiver may receive one or more analyte measurements from the sensor and may calculate one or more analyte concentrations based on the received analyte measurements. The transceiver may generate analyte concentration trends, alerts, and/or alarms based on the calculated analyte concentrations. The system may also include a display device, which may be, for example, a smartphone and may be used to display analyte measurements received from the transceiver. The display device may execute a mobile medical application. The system may include a data management system, which may be web-based.

Abstract: A non-invasive electronic patient monitor tracks one or more physiological parameters of a patient, such as intravascular volume index (IVI), extravascular volume index (EVI), total hemoglobin (SpHb), impedance, and/or weight. The patient monitor determines if one or more of the physiological parameters are within a predetermined range. The patient monitor activates an alarm if one or more of the physiological parameters are outside the predetermined range and indicates a patient can be experiencing edema and/or heart failure, or sepsis.

Abstract: Devices, systems, and methods herein relate to predicting infection of a patient. These systems and methods may comprise illuminating a patient fluid in a fluid conduit from a plurality of illumination directions, measuring an optical characteristic of the illuminated patient fluid using one or more sensors, and predicting an infection state of the patient based at least in part on the measured optical characteristic.

Abstract: Disclosed herein is a non-transitory computer-readable media having computer-executable instructions thereon. When executed by the processor of a mobile computing device, the computer-executable instructions cause the processor to wirelessly communicatively couple the mobile computing device to a GI sensor (optionally by displaying instructions on a pairing screen), display a sensor placement screen that instructs the user to place the GI sensor on a body of a patient, prompts the user to administer a GI agent into the body of the patient; transmit a signal from the mobile computing device to the GI sensor to cause the GI sensor to initiate collection of light absorbance data for calculating GI function of the patient; receive light absorbance data from the GI sensor, and store the received light absorbance data.

Abstract: The present disclosure relates to a device, method and system for calculating, estimating, or monitoring the physiological parameters of a subject. At least one processor, when executing instructions, may perform one or more of the following operations. A first signal representing a pulse wave relating to heart activity of a subject may be received. A plurality of second signals representing time-varying information on the pulse wave may be received. A blood oxygen level of the subject based on the plurality of second signals may be determined. A first feature in the first signal may be identified. A second feature in one of the plurality of second signals may be identified. A pulse transit time based on a difference between the first feature and the second feature may be computed. A blood pressure of the subject may be calculated based on the pulse transit time.

Abstract: Some embodiments disclosed herein pertain to indicator compounds used to detect the presence of and/or an amount of an analyte. In some embodiments, the indicator compounds are fusion proteins. In some embodiments, when the analyte binds to the indicator compound, the indicator compound undergoes a conformational change. In some embodiments, the conformational change results in a luminescent signal that allows quantification of the amount of analyte present.

Abstract: The present invention relates to a device for measuring a physiological parameter of a human limb such as peripheral capillary oxygen saturation. The device comprises a hollow elastic sleeve of a predetermined shape comprising a cavity having a closed-loop cross-section for enclosing the limb; first and second arms, each comprising a hinge portion between a coupling portion and a handle portion, the coupling portion of the first and second arms being adapted to be coupled, respectively, to first and second diametrically-opposite longitudinal sections of the sleeve; and a physiological sensor for interacting with the limb enclosed in said cavity. The hollow elastic sleeve holds the first and the second arms and causes their hinge portions to mutually engage to form a hinge mechanism so that, by applying a compression force on the handle portions, the first and second arms rotate about the hinge mechanism expanding the cavity, allowing the limb to be received therein.

Abstract: Devices, systems, and methods for monitoring patient hemodynamic status, systemic vascular resistance, reversal of cardiac and respiratory rates, and patient respiratory volume or effort are disclosed. A peripheral venous pressure is measured and used to detect levels, changes, or problems relating to patient blood volume. The peripheral venous pressure measurement is transformed from the time domain to the frequency domain for analysis. A heart rate frequency is identified, and harmonics of the heart rate frequency are detected and evaluated to determine, among other things, hypovolemia or hypervolemia, systemic vascular resistance, and of cardiac and respiratory rates, and patient respiratory volume or effort.

Abstract: A system and a method for creating a stable and reproducible interface of an optical sensor system for measuring blood glucose levels in biological tissue include a dual wedge prism sensor attached to a disposable optic that comprises a focusing lens and an optical window. The disposable optic adheres to the skin to allow a patient to take multiple readings or scans at the same location. The disposable optic includes a Petzval surface placed flush against the skin to maintain the focal point of the optical beam on the surface of the skin. Additionally, the integrity of the sensor signal is maximized by varying the rotation rates of the dual wedge prisms over time in relation to the depth scan rate of the sensor. Optimally, a medium may be injected between the disposable and the skin to match the respective refractive indices and optimize the signal collection of the sensor.

Abstract: The present invention relates to a wearable device for healthcare and method for using the device. More specifically, the wearable device is worn on a finger for measuring the health data of the user, selected from one or more of heart rate, blood oxygen saturation, heart rate variability. Based on the measured data, the sleep quality can be monitored and recorded. Disorders such as obstructive sleep apnea (OSA), can be detected. The wearable device may include an optical sensor coupled with or embedded in a main body including a visible light emitter, an IR light emitter and a light detector being arranged along a longitudinal direction of the finger. During operation of the wearable device, the heart rate is monitored based on a detected light signal. When the heart rate is higher than an adaptive threshold, both heart rate and blood oxygen saturation are monitored.

Abstract: The present invention relates to a sensor configuration (1) for non-invasive measurement of parameters of a body tissue with a sensor unit (10) and a sensor mat (12) for detachable placement of the sensor configuration (1) on a body surface (20). Furthermore the sensor unit (10) of the sensor configuration (1) is connectible to a contact head (16), which is designed for electrical contacting of the sensor unit (10) and for supply of light from a light source to the sensor unit (10), the sensor unit (10) being designed as a flexible printed circuit board with optical components, at least comprising a light detector device (2), in order to detect light that is emitted into the body tissue and has passed through the latter, a first contact means (30) and conducting tracks (5) for operative connection of the sensor unit (10) to the contact head (16).

Abstract: An apparatus for estimating a concentration of an analyte includes an optical sensor configured to emit light toward an object and receive light reflected from the object; and a processor configured to obtain a ratio of an absorption coefficient to a scattering coefficient based on the received light, obtain a first absorption spectrum of the object based on the obtained ratio, obtain a second absorption spectrum by eliminating a scattering correction spectrum from the first absorption spectrum, the scattering correction spectrum corresponding to a nonlinear change in the scattering coefficient according to a wavelength of the emitted light, and estimate a concentration of an analyte based on the second absorption spectrum.

Abstract: A multi-channel measurement device for measuring properties of human tissue, may comprise a microcontroller and first and second source/sensor complexes. The first source/sensor complex may include a first housing having a first measurement portion, a first light sensor coupled to the microcontroller and exposed to the first measurement portion, and a first plurality of light sources coupled to the microcontroller and exposed to the first measurement portion. The second source/sensor complex may include a second housing having a second measurement portion, a second light sensor coupled to the microcontroller and exposed to the second measurement portion, and a second plurality of light sources coupled to the microcontroller and exposed to the second measurement portion. The first and second source/sensor complexes are coupled to each other such that the first measurement portion is opposite the second measurement portion and human tissue may be placed between the first and second measurement portions.

Abstract: Health information for a woman can be used to predict timing of events related to the woman's menstrual cycle. If available, historical cycle information for a woman can be used to predict upcoming cycle events, such as the start and stop of menstruation. To improve the accuracy of those predictions, one or more health metrics are monitored for the woman that can be correlated with the menstrual cycle. These can include, for example, the resting heart rate (RHR), blood oxygen concentration (SpO2) level, and hemoglobin concentration, among other such options. The metrics are monitored over time to determine patterns that can be correlated with menstrual cycle. This information can then be used to update the predictive model, as well as to update individual event predictions. Information about the predictions, and updates to the predictions, can be surfaced accordingly.

Abstract: A sensor head for a compact oximeter sensor device includes light sources and light detectors. A compact oximeter sensor device implementation is entirely self-contained, without any need to connect, via wires or wirelessly, to a separate system unit. The sources and detectors are arranged in a circular arrangement having various source-detector pair distances that allow for robust calibration and self-correction in a compact probe. Other source-detector arrangements are also possible.

Abstract: A device to extract physiological information has at least one laser emitter. At least one optical detector is used to detect a change in optical power absorption. The laser emitter and optical detector are wire bonded into a chip scale module.

Abstract: An oxygen saturation measuring apparatus capable of measuring arterial blood oxidation saturation (SpO2), and tissue oxygen saturation (rSO2), safely, easily and economically at a desired position of a biological body for a long time continuously. A ROM stores the distance information between a light emitting unit and a light receiving unit situated corresponding to the depth of a target intended to be measured for tissue oxygen saturation, a light emission driving unit makes the light emitting unit emit light in an amount of light corresponding to the distance information, MPU makes the light emitting unit emit a pulses capable of measuring the tissue oxygen saturation, MPU applies pulse capable of measuring the tissue oxygen saturation from the light emission driving unit to the light emitting unit, and the pulse increasing unit increases the amount of pulses from MPU for a predetermined time to pulses capable of measuring the arterial blood oxygen saturation.

Abstract: An optical physiological finger sensor system including an ergonomic interface shaped into a natural curve of a user's hand and finger.

Abstract: An physiological measurement device provides a device body having a base, legs extending from the base and an optical housing disposed at ends of the legs opposite the base. An optical assembly is disposed in the housing. The device body is flexed so as to position the housing over a tissue site. The device body is unflexed so as to attach the housing to the tissue site and position the optical assembly to illuminate the tissue site. The optical assembly is configured to transmit optical radiation into tissue site tissue and receive the optical radiation after attenuation by pulsatile blood flow within the tissue.