Abstract: A pull wire attachment system for a minimally invasive medical instrument comprises an anchoring element fixedly attached to the medical instrument. The anchoring element has a first outer diameter. The system also includes a pull wire assembly comprising an elongate pull wire having a proximal end and a distal end and a securing element coupled to the distal end of the pull wire. The securing element includes a second outer diameter sized smaller than the first outer diameter of the anchoring element. The securing element is coupled to the anchoring element to prevent proximal translation of the distal end of the pull wire along a longitudinal axis of the medical instrument past the anchoring element.

Abstract: Embodiments of the present invention are directed to a liquid delivery apparatus. A non-limiting example of the apparatus includes a substrate including a cavity formed in a surface of the substrate. The apparatus can also include a membrane disposed on the surface of the substrate covering an opening of the cavity. The apparatus can also include a hydrophobic layer disposed on the membrane. The apparatus can also include a seal disposed between the membrane and the substrate, wherein the seal surrounds the opening of the cavity. The apparatus can also include an electrode layer coupled to the membrane.

Abstract: A microneedle electroporation device is provided, including a housing, a positioning member, an intermediate plate, a first microneedle assembly, a second microneedle assembly, a socket, a first wire, and a second wire. The positioning member is connected to the housing and the intermediate plate. The intermediate plate includes a plurality of first holes and a plurality of second holes. The first microneedle assembly includes a plurality of first microneedles and a first metal connecting portion connected to the first microneedles. The first microneedles pass through the first holes. The second microneedle assembly includes a plurality of second microneedles and a second metal connecting portion connected to the second microneedles. The second microneedles pass through the second holes. The first microneedle assembly and the second microneedle assembly are electrically independent of each other. The first wire connects the socket to the first metal connecting portion.

Abstract: A medical device includes a device body and an insufflation fitting coupled to and extending from the device body. The insufflation fitting includes an annular low-flow fitting and an annular high-flow fitting. The annular low-flow fitting includes a radially outward surface generally reverse of a first inner sealing surface. The inner sealing surface defines a flow passageway for insufflation gas. The annular high-flow fitting includes a second inner sealing surface extending around and radially offset from the radially outward surface of the low-flow fitting.

Abstract: The present invention relates to a catheter construction and method of use suitable for use in navigating within a body lumen or vessel, such as a vein, artery, nasal cavity, esophagus, etc. to assist in the performance of various procedures. The device can include a flexible tubular member having a proximal end, a distal end, and channel extending substantially between the proximal end and the distal end, a stiffening sleeve positioned at the distal end of the tubular member to provide stiffness thereto so that a removable procedural tool can be attached to the tubular member, and an elongated non-elastic tether situated within the channel of the tubular member and secured at one end to the distal end of the member, such that when the tether is held in tension, the tether acts to minimize the tubular member from deviating from a neutral state.

Abstract: A catheter insertion device (10) is provided for positioning and inserting a catheter (14), particularly a midline catheter into a patient. The insertion device (10) includes an introducer needle (18) that extends from the distal end of the catheter during insertion. A manually operated actuator assembly (20) is movable with respect to a housing for deploying the catheter (14) over the distal end of the introducer needle (18). A step-wise movement of the actuator (20) advances the catheter (14) in stages over the introducer needle (18). A shuttling or indexing mechanism (60, 76) advances the catheter and prevents retraction of the catheter once deployed.

Abstract: There is provided an infusion set capable of significantly reducing a period of time required for work of a worker during infusion. The infusion set includes a drip chamber, a tube which is connected to an outlet of the drip chamber, a roller clip which is provided in the tube, and an M clamp which is provided between the drip chamber and the roller clip in the tube and is used for storing liquid in the drip chamber. The tube has a first tube which can be mounted to an infusion pump device, a second tube which is connected to the outlet of the drip chamber and an inlet of the first tube, and a third tube which is connected to an outlet of the first tube. The M clamp is provided in the second tube, and the roller clip is provided in the third tube.

Abstract: A container for accommodating pharmaceutical compositions, which is installable in a medical device, is provided. The container includes a hollow cylindrical body having an open end and a dead end opposite to the open end. The dead end is closed by a bottom portion. The hollow cylindrical body and the bottom portion are formed integrally and of the same material. The bottom portion transitions into the hollow cylindrical body via a curved heel that is defined by an outer radius ro, an inner radius ri and a thickness dh in a center portion of the curved heel, wherein the following condition is fulfilled: ri+dh?ro>0 mm.

Abstract: Embodiments disclosed herein are directed to an intraosseous access system configured to confirm access to a medullary cavity. The system includes a driver housing, an access system including a drive train, a needle assembly rotatably coupled to the access system, and an aspiration system. The needle assembly can include a needle defining a lumen and an obturator disposed therein. The aspiration system can include a syringe or a vacutainer, coupled to the obturator. Sliding one of a plunger or a vacutainer proximally can withdraw the obturator from the needle lumen and place a vacuum in fluid communication with the needle lumen to draw a fluid flow therethrough. A portion of the aspiration system can rotate along with the needle assembly. Withdrawing the obturator can place the obturator within the syringe or the vacutainer mitigating needle stick injuries. If the medullary cavity has not been accessed, the obturator can be replaced.

Abstract: A fluid control component configured for controlling fluid flow through the hub of a catheter assembly during and after placement into the patient is disclosed. In one embodiment, the fluid control component comprises a body disposed within a cavity of the hub, the body being movable between a first position and a second position, wherein the body does not pierce a valve disposed in the hub when in the first position and wherein the body pierces the valve when in the second position. The body includes a conduit to enable fluid flow through an internal portion of the body when the body is in the second position, and a plurality of longitudinal ribs disposed on an exterior surface of the body. The longitudinal ribs can provide fluid flow channels between the valve and an external portion of the body when the body is in the second position.

Abstract: A catheter assembly may include a catheter adapter, which may include a distal end, a proximal end, and a lumen extending through the distal end and the proximal end. The catheter assembly may include a catheter secured within the catheter adapter and extending from the distal end of the catheter adapter. The catheter adapter may be configured to move between a first position and a second position. In response to the catheter adapter moving from the first position to the second position, an angle of the catheter adapter with respect to an insertion surface may be configured to increase, which may improve patency of the catheter assembly and alignment of a fluid path of the catheter assembly with vasculature of a patient.

Abstract: A take-home drug delivery system includes a kit container defining an inner volume, a drug delivery container preparation assembly at least partially disposed within the inner volume of the kit container, and a sterile drape at least partially disposed within the inner volume of the kit container. The drug delivery container preparation assembly includes at least a drug delivery container, a drug vial containing a drug to be administered, a tubing set, and a drug delivery container mounting apparatus. The sterile drape includes a placement legend illustrated thereon.

Abstract: A venous catheter assembly includes a hub with opposing suture wings, an extension leg coupled to the hub, and an elongate catheter tube designed for insertion into a blood vessel of a patient. The elongate catheter tube is coupled to the hub and includes at least one fluid-carrying lumen within the outer wall extending between a proximal end and a distal end of the elongate catheter tube. The fluid-carrying lumen is in fluid communication with the extension leg and an opening in the outer wall at the distal end of the elongate catheter tube. The elongate catheter tube also includes at least one terminating lumen within the outer wall extending to a closed termination point.

Abstract: An adapter for a surgical hand piece with a single lumen work tip converts the handpiece to infusion/aspiration (I/A) cleanup of lens epithelial cells in the capsular bag of the eye a patient after phacoemulsification. The adapter is in the form of a sleeve whose proximal end is to be joined to the distal end of work tip. The sleeve also has at least one aspiration hole located toward the distal end of the sleeve.

Abstract: A respiratory care system includes a user interface. A flow indicator is moveable in response to inhalation and/or exhalation, or both, by a user through the user interface. An electronic indicator is operable in response to an electronic signal transmitted in response to the movement of the flow indicator. Methods of use and assembly are also provided.

Abstract: A medical device comprising a housing defining at least one enclosure for storing agent in a first form, a force applicator within the housing and adjacent the enclosure, a drive mechanism for moving the agent toward the force applicator, wherein the force applicator defines a surface for applying a force to the agent to separate the agent into particles smaller than a size of the first form, and wherein the device defines a lumen for receiving the particles from the force applicator and for receiving a pressurized fluid to propel the particles through the lumen.

Abstract: A proximal-femur intraosseous release device includes a release mechanism. A primary fixing mechanism is provided at one end of the release mechanism, the primary fixing mechanism includes a first shell, and a second shell, a first triangular block and a second triangular block are arranged inside the first shell; the second shell is screwed to the first shell through threads, a bottom of the second shell is rotatably connected with the first triangular block, the first triangular block is slidably connected with the first shell, a bottom surface of the first triangular block is an inclined surface, the second triangular block is located at a bottom of the first triangular block, a top surface of the second triangular block is an inclined surface, and a through hole matched with the second triangular block is formed in the first shell.

Abstract: Devices and methods for filling a medicament cartridge of a pump, including a user-wearable, ambulatory infusion pump. A device for supporting a medicament cartridge can comprise a body portion resembling a tray, with recesses disposed therein to support one or more of a cartridge body, cartridge tubing, interconnect fitting, and vial adapter. The recesses of the tray may be shaped to correspond to that component intended to be placed in its respective recess so to provide a visual indication to a user how to couple and align the various components necessary to fill the cartridge.

Abstract: A delivery tube and cap are configured to be connected to a container that houses fluid to be delivered to a nasal cavity. The delivery tube includes an inner cannula that is positioned within an outer cannula. Each of the cannulas includes an outlet. The delivery tube and cap are configured to provide relative axial movement between the cannulas. The cannulas are positionable between a first axial position that aligns the outlets to deliver the fluid out of the device in a lateral direction and a second axial position that misaligns the outlets to impede the fluid from being delivered out of the device in the lateral direction.

Abstract: A medical device that includes an enclosure for storing an agent, an agitator positioned adjacent to or within the enclosure and configured to oscillate relative to the enclosure, and an outlet having a first end in fluid communication with the enclosure and a second end in fluid communication with a channel of a delivery tube. Oscillation of the agitator causes the agent to move toward the outlet.