Abstract: A proximal-femur intraosseous release device includes a release mechanism. A primary fixing mechanism is provided at one end of the release mechanism, the primary fixing mechanism includes a first shell, and a second shell, a first triangular block and a second triangular block are arranged inside the first shell; the second shell is screwed to the first shell through threads, a bottom of the second shell is rotatably connected with the first triangular block, the first triangular block is slidably connected with the first shell, a bottom surface of the first triangular block is an inclined surface, the second triangular block is located at a bottom of the first triangular block, a top surface of the second triangular block is an inclined surface, and a through hole matched with the second triangular block is formed in the first shell.

Abstract: Devices and methods for filling a medicament cartridge of a pump, including a user-wearable, ambulatory infusion pump. A device for supporting a medicament cartridge can comprise a body portion resembling a tray, with recesses disposed therein to support one or more of a cartridge body, cartridge tubing, interconnect fitting, and vial adapter. The recesses of the tray may be shaped to correspond to that component intended to be placed in its respective recess so to provide a visual indication to a user how to couple and align the various components necessary to fill the cartridge.

Abstract: A delivery tube and cap are configured to be connected to a container that houses fluid to be delivered to a nasal cavity. The delivery tube includes an inner cannula that is positioned within an outer cannula. Each of the cannulas includes an outlet. The delivery tube and cap are configured to provide relative axial movement between the cannulas. The cannulas are positionable between a first axial position that aligns the outlets to deliver the fluid out of the device in a lateral direction and a second axial position that misaligns the outlets to impede the fluid from being delivered out of the device in the lateral direction.

Abstract: A medical device that includes an enclosure for storing an agent, an agitator positioned adjacent to or within the enclosure and configured to oscillate relative to the enclosure, and an outlet having a first end in fluid communication with the enclosure and a second end in fluid communication with a channel of a delivery tube. Oscillation of the agitator causes the agent to move toward the outlet.

Abstract: The invention includes a transradial introducer sheath support and integral hemostasis device. The device includes a wristband and an introducer sheath support mount attached to the wristband. The wristband is made from a flexible and resilient material that is applied to the distal forearm of the patient or other desired location on the patient. The support mount may be a molded unitary structure, such as made from a thermoplastic material, and is attached directly to the outer surface of the wristband. An inflatable hemostatic element is incorporated in the wristband and mounted to an interior surface of the wristband. The hemostatic element may be selectively inflated to apply pressure to a radial access point of the patient during and after removal of the transradial introducer sheath from the patient. Another embodiment provides a hemostatic element by a rotatable clasp of the sheath support mount.

Abstract: A catheter sheath device may include an elongate member and a moveable member. The elongate member may include a first lumen, and the moveable member may include a second lumen. The moveable member may be physically coupled to a portion of the elongate member to permit relative movement therebetween. A first relative movement between the moveable member and a portion of the elongate member may cause the second lumen to be positioned at a first location that permits delivery of at least a portion of a catheter into the second lumen but not into the first lumen from the second lumen. A second relative movement between the moveable member and the portion of the elongate member may cause the second lumen to be positioned at a second location that permits delivery of the at least the portion of the catheter through both the second lumen and the first lumen.

Abstract: An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall.

Abstract: A device for opening and closing an infusion tube clamp includes a slide link which is axially arranged to be movable on a flap and includes at least one projecting locking element for closing an infusion tube clamp. An infusion tube clamp includes a first clamping leg and a second clamping leg pivotally connected to each other at one end, and a keeper plate which is arranged on the first clamping leg. At the locking element, the slide link includes a slide link ramp at which a switching cam of the keeper plate is adapted to slide into a stress-free final closing position.

Abstract: A first member (10) and a second member (20) are coupled to each other in a coupling portion (100). The first member includes, on the opposite side to the coupling portion, a main portion (51) that is connectable to a counterpart connector. The main portion and the second member are in communication with each other via a flow channel (102). One of the first member and the second member includes an outer cylindrical portion (30), and the other of the first member and the second member includes an inner cylindrical portion (40). In the coupling portion, the inner cylindrical portion is fitted in the outer cylindrical portion. The outer cylindrical portion includes a first engagement portion (31) and an abutment portion (35). The inner cylindrical portion includes a second engagement portion (41) that engages the first engagement portion, and a leading end (45) that is a front end of the inner cylindrical portion in a direction in which the inner cylindrical portion is fitted into the outer cylindrical portion.

Abstract: An automatic injection device is provided, where the device includes a syringe carrier and a retraction assembly. The syringe carrier may include two identical parts that are discrete from one another and interlock with one another. Carrier includes a cushion to support the syringe. Protrusions may be provided on cushion to further support syringe. The retraction assembly includes a shuttle and a follower, the follower having a moveable latch. The follower has a coupled configuration in which the latch is biasedly coupled to the shuttle, and a decoupled configuration in which the latch is in sliding engagement with a curvilinear surface of the shuttle.

Abstract: A needleless connector may include a housing having a proximal end, a distal end, and an inner surface defining an internal cavity extending between the proximal and distal ends. A compressible valve may be disposed within the internal cavity. The compressible valve may include a head portion, a flange portion for securing the compressible valve in the housing, and a body portion extending between the head portion and the flange portion. The body portion may include a cylindrical outer surface having an external notch extending along a portion of a circumference of the cylindrical outer surface and recessed radially-inward from the cylindrical outer surface. The body portion may further include a planar face extending distally from the external notch and disposed between the external notch and the flange portion. The planar face may be recessed radially inward relative to at least a portion of the cylindrical outer surface.

Abstract: Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject).

Abstract: An enteral feeding connector, coupling or syringe tip configured for compatibility with blenderized feeding applications. The connector, coupling or syringe tip has a minimum internal bore dimension greater than the standard ENFit coupling specifications, to provide improved delivery of blenderized food.

Abstract: A system for accessing a patient's vascular system may have a tube with a wall that defines an exterior surface and lumen with a proximal end and a distal end, and a guidewire that is deployable, by sliding distally, from a retracted position in which the guidewire resides in the lumen, to a deployed position in which the guidewire extends beyond the distal end. The system may further have a retraction mechanism that can be actuated to retract the guidewire from the deployed position to the retracted position, or a protective shield that can be actuated to extend distally from the distal end of the tube to cover the guidewire in the deployed position.

Abstract: An improved system and method for a syringe capable of reducing re-usage and limiting wasted contents. The syringe has a plunger with a plunger plug that extends beyond the barrel of the syringe when the contents are fully dispensed and prevents the plunger from being drawn backward. The plunger may also consist of a two-piece design that separates upon exceeding a predetermined force when attempting to draw the plunger backward after use.

Abstract: An assembly for a drug delivery device and an associated drug delivery device are provided. The device has a drug delivery device housing and a medicament contained in the drug delivery device housing. A clutch is established between the dose knob and the dial link to prevent inadvertent proximal axial movement of the lead screw away from the cartridge piston, which can lead to dosing inaccuracies.

Abstract: Provided herein are devices useful in processing fat for fat grafting and for delivering fat tissue grafts to a patient. Also provided are devices and methods for fat grafting and for treatment of plantar fasciitis.

Abstract: A system for measuring drip rate may include a drip chamber device comprising an elongated body including an inner surface defining a chamber, and a drip rate measurement device. The drip chamber may be fluidly coupled to a container containing an IV fluid configured to drip droplets of the IV fluid into the chamber. The drip rate measurement device may include a housing configured to be mounted to the elongated body of the drip chamber, and a load cell transducer mounted in the elongated body and extending into the chamber. The load cell transducer may be configured to measure a weight of the droplets of the IV fluid and convert the weight into an electrical signal. The drip rate measurement device may further include a controller electrically coupled to the load cell transducer to process the electrical signal and output at least one parameter associated with the IV fluid.

Abstract: An aspiration and injection device is provided that can allow for ergonomic, safe, and precise aspiration of a target site and ejection of a medicament to the target site. The device can include a syringe barrel, a flange extender couplable to the barrel, and plunger that can be engaged by a hand and/or one or more finger of a user to perform aspiration and injection at a target site.

Abstract: A drug storage and dispensing system that includes a packaging unit and an injection device for pre-filled containers having a needle shield and containing a medication is disclosed. The drug storage and dispensing system of the present disclosure provides for drug administration while minimizing the space occupied by such containers in the cold chain. The packaging unit minimizes the risk of a needle-stick injury, as a healthcare worker does not have to manually remove the needle shield. The injection device provides a novel way of auto-disabling a container, such as a syringe, as a plunger rod is not engaged with the container until the container is actually used. The drug storage and dispensing system provides for a reduction in the number of steps required to perform an injection, and thus a productivity and efficiency gain in mass immunization campaigns.