Abstract: The present invention relates to novel compounds of the formula (I): ##STR1## wherein Q.sub.3 R.sub.3 and Q.sub.8 R.sub.8 are described herein. The compounds possess PDE-IV inhibitory activity and improved selectivity with regard to PDE-III inhibition. Also disclosed are pharmaceutical compositions and methods of treatment utilizing the disclosed compounds.
Type:
Grant
Filed:
June 11, 1997
Date of Patent:
May 23, 2000
Assignee:
Euro-Celtique S.A.
Inventors:
David Cavalla, Peter Hofer, Mark Chasin