Patents Examined by Mark Bockelman
  • Patent number: 7090648
    Abstract: Methods of medical treatment and diagnosis using mediators released by endothelial cells stimulated by external addition of pulses to the circulation are disclosed. The external pulses produce circumferential shear stress in body fluid channels that subsequently stimulates the endothelial cells to produce mediators that become available for therapeutic and diagnostic purposes. The preferred means of adding external pulses is the mechanical inducement of periodic acceleration of the body or parts of the body by a reciprocating motion platform.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: August 15, 2006
    Assignee: Non-Invasive Monitoring Systems, Inc.
    Inventors: Marvin A. Sackner, D. Michael Inman
  • Patent number: 7092763
    Abstract: An implantable neural stimulation system, such as an auditory Fully Implantable System (FIS), includes: (1) an implanted device capable of providing desired tissue or nerve stimulation; and (2) a remote control unit that provides a mechanism for readily controlling the implant device. The remote control unit uses a first signal path to send signals to the implant device, and a second signal path to receive signals from the implant device. The combination of these two signal paths provides a full-duplex channel between the remote control unit and the implant device through which appropriate control and status signals may be sent and received. In one embodiment, the first signal path comprises an audio signal path through which audio control signals, e.g., a tone sequence or a 32-bit word FSK modulated between 300 and 1200 Hz, are sent; and the second signal path comprises a RF signal path through which a BPSK, QPSK or FM modulated RF signal is received.
    Type: Grant
    Filed: November 30, 2004
    Date of Patent: August 15, 2006
    Assignee: Advanced Bionics Corporation
    Inventors: Glen A Griffith, Michael A Faltys
  • Patent number: 7083580
    Abstract: A treatment method and apparatus for providing a substance to be absorbed onto a surface of a patient's skin, includes applying the substance onto the surface of the patient's skin by way of a probe head that provides, at the same time: i) bursts of electrical pulses to the skin surface, and ii) vibrations to the skin surface. The vibrations are applied to the skin surface at substantially a same frequency rate, a first harmonic of the same frequency rate, and/or a second harmonic of the same frequency rate, as a burst rate of electrical pulses being applied to the skin surface.
    Type: Grant
    Filed: February 24, 2004
    Date of Patent: August 1, 2006
    Assignee: Mattioli Engineering Ltd.
    Inventor: Gian Franco Bernabei
  • Patent number: 7082333
    Abstract: An apparatus and method that allows a patient to access stored preset patient therapy programs, that are resident in a medical device, and to create personalized therapy programs or automatic timing therapy programs from preset therapy programs to accommodate the patient's particular activity. Alternatively, the patient can select and access stored preset patient therapy programs and combine at least two modified or unmodified preset therapy programs to create personalized therapy programs.
    Type: Grant
    Filed: April 27, 2000
    Date of Patent: July 25, 2006
    Assignee: Medtronic, Inc.
    Inventors: Ruth Elinor Bauhahn, John W. Forsberg, Steven James Nelson
  • Patent number: 7079893
    Abstract: A hybrid battery power source for implantable medical use provides a generally constant low internal resistance during discharge and avoids voltage delays of the type that develop as a result of run down-induced resistance increase in Li/SVO cells. The hybrid battery power source utilizes two batteries or cells, one being a primary cell of relatively high energy density and the other being a secondary cell of relatively low internal resistance that is rechargeable. The primary and secondary cells are connected in a parallel arrangement via a voltage boost/charge control circuit that is powered by the primary cell and adapted to charge the secondary cell while limiting charge/discharge excursions thereof in a manner that optimizes its output for high energy medical device use. The energy storage capacitors of the medical device in which the hybrid battery power source is situated are driven by the secondary cell. The primary cell is used to as an energy source for recharging the secondary cell.
    Type: Grant
    Filed: January 24, 2004
    Date of Patent: July 18, 2006
    Assignee: GentCorp Ltd.
    Inventors: Wilson Greatbatch, Jeffrey Deal
  • Patent number: 7079897
    Abstract: A system and method for automatically adjusting the operating parameters of a rate-adaptive cardiac pacemaker. In accordance with the method, maximum exertion levels attained by the patient are measured at periodic intervals and stored. The stored maximum exertion levels may then be used to update a long-term maximal exertion level, and the slope of the rate-response curve is adjusted to map the updated long-term maximal exertion level to a maximum allowable pacing rate. The stored maximum exertion levels may also be used to update a sensor target rate which is used to adjust the slope of the rate response curve.
    Type: Grant
    Filed: May 6, 2004
    Date of Patent: July 18, 2006
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Weimin Sun, Bruce R. Jones, Douglas J. Lang, Donald Hopper
  • Patent number: 7076306
    Abstract: A gastroelectric stimulator comprises a neurostimulator for producing a stimulation signal, at least one electrical lead, and at least two electrical contacts. The electrical lead has a proximal end and a distal end, the proximal end being connected to the neurostimulator and the distal end positionable in a lead position within the patient's abdomen. The electrodes are carried near the electrical lead distal end. The electrodes are electrically connected through the electrical lead to the neurostimulator to receive the stimulation signal and convey this signal to an electrode position within the patient's digestive system. The stimulation signal is adapted to influence pancreatic secretions.
    Type: Grant
    Filed: July 26, 2004
    Date of Patent: July 11, 2006
    Assignee: Medtronic, Inc.
    Inventors: Benoit Marchal, Warren Starkebaum
  • Patent number: 7076295
    Abstract: An implementation of a technology is described herein for automatically adjusting the magnitude of a defibrillation shock of an implantable cardiac therapy devices (ICTDs) to an improved magnitude. With the technology described herein, an ICTD (such as a defibrillator) automatically determines an improved defibrillation shock energy (DFSE) and automatically adjusts the DFSE so that it delivers a rescuing shock at that level. The defibrillator automatically adjusts the DFSE to an improved level based upon historical and present factors. This abstract itself is not intended to limit the scope of this patent. The scope of the present invention is pointed out in the appending claims.
    Type: Grant
    Filed: October 17, 2001
    Date of Patent: July 11, 2006
    Assignee: Pacesetter, Inc.
    Inventor: Mark W. Kroll
  • Patent number: 7072721
    Abstract: A vest for providing electrical stimulation is disclosed. The vest includes front and rear sections and a controller. Left front and right front electrodes are provided on interior surfaces of the front section, and left rear and right rear electrodes are provided on interior surfaces of the rear section. The controller is provided on an exterior surface of the front section and provides selectively adjustable electrical pulse signals to the electrodes via wires routed over the exterior surface of the front and rear sections to the electrodes through respective openings provided in the front and rear sections. The electrodes and the front and rear sections include means for positional adjustment of the electrodes on the interior surfaces of the front and rear sections. The vest can be used for electrical stimulation of muscles or nerves of the abdomen and back for users having varying body types and sizes.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: July 4, 2006
    Inventor: Cecilio Trent
  • Patent number: 7072716
    Abstract: Apparatus and technique for compensating the potential detected by amplifier circuits for sensing cardiac activity in an active implantable medical device, such as in a pacemaker, defibrillator, cardioverter and multisite device. This device includes circuits for delivering to a cardiac cavity stimulation pulses of predetermined voltage levels and pulse widths, and circuits for sensing cardiac activity comprising an amplifier of signals sensed by an intracardiac electrode, delivering at its output a value of measured potential (Pmeasured) consecutive with the application of a stimulation pulse (I). The device includes circuits for determining a response potential specific to that amplifier, independently of the presence or absence of a myocardial depolarization.
    Type: Grant
    Filed: July 10, 2002
    Date of Patent: July 4, 2006
    Assignee: Ela Medical S.A.
    Inventor: Cyrille Casset
  • Patent number: 7066910
    Abstract: An method and system that allows a patient to access stored preset patient therapy programs, that are resident in a medical device such an implantable pump or a combination medical device having an implantable pump and a implantable neural stimulator, and to create personalized therapy programs or automatic timing therapy programs from preset therapy programs to accommodate the patient's particular activity. Alternatively, the patient can select and access stored preset patient therapy programs and combine at least two modified or unmodified preset therapy programs to create personalized therapy programs.
    Type: Grant
    Filed: October 18, 2001
    Date of Patent: June 27, 2006
    Assignee: Medtronic, Inc.
    Inventors: Ruth Elinor Bauhahn, John W. Forsberg, Steven James Nelson, Kenneth Timothy Heruth
  • Patent number: 7069081
    Abstract: The present invention is directed to a header assembly attachable to a medical device for the purpose of connecting its output terminals to at least one lead, the lead terminating at a target organ or portion of the body intending to be assisted. A number of leads are connectable to the header, including single and coaxial leads. The header assembly may be molded directly to the medical device or preformed and then attached to the device casing, either by mechanical fastener and/or chemical adhesive.
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: June 27, 2006
    Assignee: Wilson Greatbatch Ltd.
    Inventors: James C. Biggs, Norbert W. Frenz, Jr., David A. Faltisco
  • Patent number: 7065408
    Abstract: A method for restoring functional ambulation in subjects with incomplete spinal cord injuries which includes partial weight bearing therapy followed by epidural spinal cord stimulation (ESCS) to facilitate partial weight bearing therapy and over-ground walking. Electrical epidural stimulation (EES) is generated by an implanted device during partial weight bearing therapy on a treadmill. The subject is then transitioned to full weight bearing gait training on a treadmill with EES to over-ground gait training with EES and a walker, and finally to full weight bearing independent stepping over-ground with EES with or without an assistive device.
    Type: Grant
    Filed: January 8, 2002
    Date of Patent: June 20, 2006
    Inventors: Richard M. Herman, Stephen C. D'Luzansky, Jiping He, James D. Sweeney
  • Patent number: 7062323
    Abstract: A cardiac rhythm management system includes an operational mode in which ventricular pacing pulses are delivered at a rate that tracks a sinoatrial rate up to an appropriate maximum atrial tracking rate (MATR) value determined by the system. In one example, the MATR value is based on a patient activity level and a hemodynamic maximum rate (HMR) determined from a QRS-to-S2 interval, where S2 is an accelerometer-generated fiducial correlative to aortic valve closure (AVC). In a further example, a correlation between the QRS-to-S2 interval and heart rate is established, and the MATR is based on the patient activity level and heart rate. In a further example, a lower rate threshold for providing antitachyarrhythmia therapy is modified based on the MATR. For example, when the MATR exceeds a default value of the antitachyarrhythmia therapy lower rate threshold, the threshold tracks the MATR.
    Type: Grant
    Filed: October 19, 2001
    Date of Patent: June 13, 2006
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Gerrard M. Carlson, Julio C. Spinelli, Qingsheng Zhu
  • Patent number: 7048680
    Abstract: A multilumen catheter that maximizes the blood flow into and out of the patient's vasculature while also providing for passive and/or active perfusion of tissue downstream of where the catheter resides in the vasculature. The inventive catheter comprises a proximal end, a first distal and a second distal end. Lumens extending from the proximal end to each of these distal ends provide for blood circulation within one or between two blood vessels. At least one aperture in one of the lumens positioned near the proximal end provides for active perfusion of blood to the patient's vasculature downstream of where the aperture resides in the vasculature when the catheter is inserted into the patient for treatment. The inventive catheter may comprise a third lumen positioned entirely within the patient's vasculature, providing passive perfusion of blood to the patient's vasculature downstream of where the third lumen resides in the vasculature when the catheter is inserted into the patient for treatment.
    Type: Grant
    Filed: June 6, 2001
    Date of Patent: May 23, 2006
    Assignee: Orqis Medical Corporation
    Inventors: Anthony Viole, Laksen Sirimanne, Steven F. Bolling, Shawn O'Leary, Wolfgang Werner
  • Patent number: 7047066
    Abstract: A cardiac rhythm management system that includes a pacemaker configured for biventricular pacing and an external programmer with an associated display for displaying electrogram data and markers representing ventricular events. Associated with each marker are intraventricular intervals designed to relate information to a user in a manner suited for ventricular resynchronization pacing.
    Type: Grant
    Filed: March 3, 2004
    Date of Patent: May 16, 2006
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Scott Vanderlinde, Jeffrey E. Stahmann, Rene H. Wentkowski, David Ternes, James Kalgren
  • Patent number: 7043304
    Abstract: A method of controlling an implantable neural stimulation system, such as an auditory Fully Implantable System (FIS), uses a first signal path to send signals to the implant device, and a second signal path to receive signals from the implant device. The combination of these two signal paths provides a full-duplex channel between the remote control unit and the implant device through which appropriate control and status signals may be sent and received. In one embodiment, the first signal path comprises an audio signal path through which audio control signals, e.g., a tone sequence or a 32-bit word FSK modulated between 300 and 1200 Hz, are sent; and the second signal path comprises a RF signal path through which a BPSK, QPSK or FM modulated RF signal is received. The full-duplex channel allows operation of the remote control unit, i.e., allows signals to be successfully sent to and received from the implant device, from as far away as 45–60 cm from the implant device.
    Type: Grant
    Filed: November 30, 2004
    Date of Patent: May 9, 2006
    Assignee: Advanced Bionics Corporation
    Inventors: Glen A. Griffith, Michael A. Faltys
  • Patent number: 7043297
    Abstract: A reservoir electrode assembly of the present invention for an iontophoretic drug delivery device includes an electrode and a hydrophilic reservoir situated in electrically conductive relation to the electrode. The hydrophilic reservoir is formed from a bibulous hydrophilic cross-linked polymeric material having a first surface and a second surface that is adhesively adherent to the electrode. The first surface of the polymeric material is releasably adhesively adherent when applied to an area of a patient's skin. The polymeric material has a cohesive strength forms an adhesive bond with a bond strength between the second surface of the polymeric material to the electrode that is greater than the cohesive strength of the polymeric material.
    Type: Grant
    Filed: January 19, 2005
    Date of Patent: May 9, 2006
    Assignee: Vyteris, Inc.
    Inventors: Preston Keusch, NRK Vilambi, Bruce Michael Eliash
  • Patent number: 7043295
    Abstract: Methods and systems for treating patients suffering from eating disorders, e.g. obesity, through the dispensation of a drug by an implantable infusion pump (IIP) delivering drug into the cerebral spinal fluid (CSF) at a site of the intrathecal space in amounts and at times effective to suppress the patient's appetite through interaction of the drug transported through the CSF with receptors in the brain. Delivery of a programmed drug dosage is preferably by one of time-out of programmed time(s) of day, a command received from the patient, or a trigger signal developed from a sensed GI tract signal accompanying peristalsis.
    Type: Grant
    Filed: April 26, 2002
    Date of Patent: May 9, 2006
    Assignee: Medtronic, Inc.
    Inventor: Warren L. Starkebaum
  • Patent number: 7039456
    Abstract: This invention relates to a conductance path mechanism of a wireless heartbeat transmitter comprising a circuit board, a spiral spring, a U-shaped contact rod integrally molded to both side of a bottom cover and a rubber conductible sheet. A horizontal portion of said U-shaped contact rod is totally inserted inside a foundation of a bottom cover to form a steady mechanism of the present invention.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: May 2, 2006
    Inventor: Shui Jung Chen