Abstract: Provided are a device and method for receiving a fetal heart rate (FHR) signal at each interval during a monitoring period, receiving a uterine pressure (UP) signal at each of the intervals to obtain a plurality of FHR-UP signal pairs, and extracting a feature value for each FHR-UP signal pair, with the feature value being extracted from a predefined alphabet of feature values.
Type:
Grant
Filed:
November 28, 2017
Date of Patent:
August 6, 2019
Assignee:
The Research Foundation for The State University of New York
Inventors:
Shishir Dash, J. Gerald Quirk, Petar Djuric
Abstract: A method of enhancing the permeability of a biological membrane, including the skin or mucosa of an animal or the outer layer of a plant to a permeant is described utilizing microporation of selected depth and optionally one or more of sonic, electromagnetic, mechanical and thermal energy and a chemical enhancer. Microporation is accomplished to form a micropore of selected depth in the biological membrane and the porated site is contacted with the permeant. Additional permeation enhancement measures may be applied to the site to enhance both the flux rate of the permeant into the organism through the micropores as well as into targeted tissues within the organism.
Type:
Grant
Filed:
June 14, 1999
Date of Patent:
February 6, 2001
Assignees:
SpectRx, Inc., Altea Technologies, Inc.
Abstract: Refillable immunoisolatory neurological therapy devices for local and controlled delivery of a biologically active factor to the brain of a patient. The devices include a cell chamber adapted for infusion with nsecretory cells and having at least one semipermeable or permselective surface across which biologically active factors secreted by the cells can be delivered to the brain. The devices also include means for introducing secretory cells into the cell chamber, and means for renewing the cells or cell medium.
Type:
Grant
Filed:
May 26, 1995
Date of Patent:
September 10, 1996
Assignee:
Brown University Research Foundation
Inventors:
Patrick Aebischer, Paul C. DiCesare, Moses Goddard, Paul J. Mulhauser