Abstract: Provided is a photoplethysmogram (PPG) sensing module including one or more light sources that emit light to a user; a plurality of optical sensors that receive reflected light from the user and generate sensing signals, each of the sensing signals being generated by one of the optical sensors; a read-out signal generating circuit that receives the sensing signals from the optical sensors and generate read-out signals by performing an analog-to-digital conversion on the sensing signals; and a signal processing circuit that receives the read-out signals, classifies the read-out signals according to one or more movement patterns of the user, measures a movement component of the user based on the classified read-out signals, and generates a PPG signal in which the movement component is removed.

Abstract: The present disclosure relates to systems and methods to perform a surgical procedure. The systems and methods utilize MRI-compatible fiducial markers including a body having at least one feature configured to receive an MRI-compatible and MRI-visible material and to allow registration of a navigational tool. The MRI-compatible fiducial markers can be affixed to a bone of a patient. The registered navigational tool can be used to advance a surgical tool along a navigational path to perform a surgical procedure.

Abstract: A device of an embodiment includes: an optical mechanism; a control computation unit that controls driving of the optical mechanism, acquires a tomographic image of skin by processing an optical interference signal from an optical system, and calculates a network of blood vessels on the basis of the tomographic image; and a display device that displays an image of the network of blood vessels. The control computation unit sets a reference profile obtained by function approximation of an intensity profile in a depth direction of the acquired tomographic image, calculates a difference between an intensity value on the reference profile and an actual intensity value as an outlier V, the intensity values being those in the depth direction in the tomographic image, determines, as blood vessels or blood vessel candidates, coordinates with the outliers V within a predetermined blood vessel determination range, and calculates the network of blood vessels.

Abstract: A method that includes transmitting coded waveforms simultaneously on multiple elements for several frames, constructing a first multi-input, single output (MISO) system from the codes to model transmit-receive paths, solving system and RF data observation by linear model theory, giving an IR set for the medium, and applying the estimates to a secondary MISO system, constructed by analogy to the first, but with pulses convenient for beamforming in the form of a focused set of single-cycle pulses for ideal focused reconstruction.

Abstract: A device includes a syringe, which has a tip, plunger, and barrel containing a fluid. The device also includes a needle electrode coupled to the tip of the syringe, a release component, and a control component configured to receive electrical measurements made by the needle electrode, determine impedance values from the electrical measurements, and identify a target tissue based on the impedance values. In response to the identification, the control component generates instructions to reposition a release component. A method includes receiving electrical measurements from a needle electrode, determining impedance values based on the electrical measurements. A target tissue is identified based on the impedance values, and a release component is repositioned in response.

Abstract: A computer-assisted imaging and localization system assists the physician in positioning surgical effecters, such as implants, tools and instruments, within a surgical site in a patient's body. The system displays overlapping images—one image of the surgical site with the patient's anatomy and another image showing the surgical effecter(s). The overlapping image of the surgical effecter(s) is moved over the static image of the anatomy as the implant/instrument is moved. The movement of the surgical effecter(s) is determined in a three-dimensional coordinate system at a home base location in the patient's anatomy, which home base can be moved during the procedure without interrupting the displays of the overlapping images.

Abstract: Systems and method for remote field measurement-based mapping of anatomical structures (e.g., using impedance image of electrical fields) are described. In some embodiments, an image of features within a target region is produced by analysis of a spatial pattern of field measurements made in a measurement region remote from the target region features; for example, but not exclusively, by treating the spatial arrangement of field measurements in some portion of the measurement region as indicating the spatial (e.g., angular and/or distance) arrangement of features (e.g., anatomical structure of topography and/or tissue type) in the target region.

Abstract: A PPG PRV device for generating a PRV parameter of a PPG signal (20) as an estimation of a HRV parameter of an ECG signal. The PPG PRV device employs a PPG probe (700) and a PPG PRV controller (710). In operation, the PPG probe (700) generate a PPG signal (20). In response thereto, the PPG PRV controller (710) generates a normalized PPG signal (20?) including a plurality of pulses of the PPG signal (20) designated as normal pulses by the PPG PRV controller (710) and excluding at least one pulse of the PPG signal (20) designated at least one abnormal pulse by the PPG PRV controller (710), wherein the normalized PPG signal (20?) is HRV comparable to the ECG signal. The PPG PRV controller (710) derives the PRV parameter from a HRV measurement of the normalized PPG signal (20?).

Abstract: The present disclosure provides implants, sensor modules, networks, and methods configured to establish transcutaneous power and transcutaneous bidirectional data communication using ultrasound signals between two or more medical devices located on and within a body of a patient.

Abstract: The present invention relates to a parathyroid sensing system, and includes: a modulator for generating a modulation signal having a predetermined frequency; a lock-in amplifier and a light source which receive information on the modulation signal; an excitation filter for transmitting, among light emitted from the light source, only excitation light that excites parathyroid glands; an emission filter connected to a probe and selectively transmitting only fluorescence emitted from the parathyroid glands; a near-infrared sensor for sensing the autofluorescence that has passed through the emission filter, and converting the sensed autofluorescence into an electric signal; and a speaker for generating an alarm through the electric signal. Through the present invention, the locations of the parathyroid glands may be precisely identified even when lights are turned on in an operating room, and convenience may be provided by alerting a surgeon by means of an alarm when the parathyroid glands are detected.

Abstract: Exemplary systems, devices, methods, apparatus and computer-accessible media for providing and/or utilizing optical frequency domain imaging (OFDI) and fluorescence of structures and, e.g., multimodality imaging using OFDI techniques and fluorescence imaging techniques are described. For example, an arrangement can provide at least one electro-magnetic radiation to an anatomical structure. Such exemplary arrangement can include at least one optical core and at least one cladding at least partially surrounding the fiber(s). A region between the optical core(s) and the cladding(s) can have an index that is different from indexes of the optical core(s) and the cladding(s). The arrangement can also include at least one apparatus which is configured to transmit the radiation(s) via the optical core(s) and the cladding(s) to the anatomical structure.

Abstract: According to various embodiments, an electronic device may comprise: a housing comprising an inner space; a sensor structure positioned in the housing and exposed through a part of the housing, the sensor structure comprising a substantially transparent plate comprising a first surface facing away from the inner space and a second surface facing away from the first surface; a support structure positioned in the inner space so as to face the transparent plate; at least one light-emitting element mounted on the support structure while being spaced apart from the second surface and inserted between the second surface and the support structure; a spatial light modulator (SLM) disposed between the transparent plate and the LED while being spaced apart from the light-emitting element; a light-receiving element mounted on the support structure and positioned between the second surface and the support structure while being adjacent to a side surface of the light-emitting element; and a processing circuit comprising a

Abstract: Devices and systems are provided for tracking a position and orientation of a handheld implement, such that the handheld implement may be trackable with an overhead tracking system. A support member secures one or more markers relative to a longitudinal portion of the handheld implement, and a marker plane containing the markers is orientated an angle relative to a longitudinal axis of the longitudinal portion. A marker assembly may include a support member for supporting the markers, and a connector for removably attaching the marker assembly to one or more handheld implements. The marker assembly may be configured to be removably attachable to a plurality of connection adapters, where each connection adapter is further connectable to a handheld implement, optionally at a calibrated position, such that a single connection adapter can be optionally employed to track a plurality of handheld implements. The handheld implement may be a medical instrument.

Abstract: An infrared imaging signal is generated to illuminate tissue. An infrared image of an exit signal of the infrared imaging signal is captured. The infrared imaging signal is within a frequency band.

Abstract: Disclosed is an optical coherence tomography (OCT) system according to an exemplary embodiment of the present disclosure.

Abstract: Retinal diseases, such as age-related macular degeneration (AMD), are the leading cause of blindness in the elderly population. Since no known cures are currently present, it is crucial to diagnose the condition in its early stages so that disease progression is monitored. Systems and methods for detecting and mapping the mechanical elasticity of retinal layers in the posterior eye are disclosed herein. A system including confocal shear wave acoustic radiation force optical coherence elastography (SW-ARF-OCE) is provided, wherein an ultrasound transducer and an optical scan head are co-aligned to facilitate in-vivo study of the retina. In addition, an automatic segmentation algorithm is used to isolate tissue layers and analyze the shear wave propagation within the retinal tissue to estimate mechanical stress on the retina and detect early stages of retinal diseases based on the estimated mechanical stress.

Abstract: A needle guide for use with a handheld probe having a connector protruding from a probe surface. The needle guide can include an upper portion including an upper surface, a lower portion defining a cavity to receive the connector of the handheld probe, and a needle channel. The needle channel can extend from a proximal portion of the upper surface to a distal end of the upper surface. The needle channel can have a fixed size. The needle guide can include a guide surface extending into the upper portion and the lower portion of the needle guide at a proximal end of the needle guide. The guide surface can include a concave shape with a conical surface that funnels into a proximal end of the needle channel.

Abstract: Disclosed is a patient positioning assembly for orientating a patient with respect to a radiation source. The patient positioning assembly includes a translatable member movable in a vertical direction between a vertically downwards first position and a vertically upwards second position. The patient positioning assembly further includes a patient support assembly mounted to the translatable member and adapted to rotate relative to the translatable member about a vertical axis. The patient support assembly is configurable between a first orientation, which sustains the patient in a seated position, and a second orientation, which sustains the patient in a generally standing position.

Abstract: The invention provides a magnetic inductive sensing device (30) comprising a loop antenna (10) for inductively coupling with electromagnetic (EM) signals emitted from a medium in response to stimulation of the medium with electromagnetic excitation signals. The device includes an electromagnetic shield (36) element which is arranged such as to intercept electromagnetic signals travelling to or from the antenna. The shield element is formed of conductive material such as to block electrical field components of incident signals but further incorporates a non-conductive gap in the material so as to prevent the formation of eddy currents. A loop of the antenna is broken by an opening, the opening being bridged by a capacitor, and the device comprises a signal processing means which is electrically coupled to the antenna via only a single point of the antenna, located to one side of the opening.

Abstract: Systems and methods are provided for motion corrected wide-band pulse inversion ultrasonic imaging. A first pulse is transmitted, a second pulse is then transmitted after a delay, with the second pulse having different polarity. Echoes of the first pulse and the second pulse are received, using a reception bandwidth that enables capturing at least a portion of a fundamental portion of each pulse. The echoes are processed, and corresponding ultrasound images are generated based on processing. The processing includes determining displacement data between the first pulse echo and the echo of the second pulse for at least one structure in an imaged area; determining one or more displacement corrections based on the displacement data; applying at least one displacement correction to at least one of the first pulse echo and the echo of the second pulse; and combining the first pulse echo and the echo of the second pulse.