Abstract: A patient interface assembly includes a housing that defines an inlet port and an outlet port. A jet pump receives pressurized gas flow from the inlet port and delivers the gas flow to the outlet port. A nebulizer is fluidly coupled to the outlet port and positioned to introduce medication into the gas flow and deliver medicated gas flow to a patient.

Abstract: Systems and methods are described for application of a transitory corrective modification to a hot-wire anemometer flow voltage and/or calculated flow rate to compensate for transient thermal response of the anemometer during a change in mixture of a mixed gas being measured. According to one embodiment a method of applying the transitory corrective modification is provided. An output signal of an exhalation flow sensor of a medical ventilator is received. The flow sensor includes a hot-wire anemometer. The output signal is indicative of a rate of flow of expired gas by a patient. Transient thermal response of the hot-wire anemometer is compensated for by applying a corrective modification to the output signal or a value based thereon. The corrective modification is based at least in part on a fraction of inspired oxygen (FiO2) being supplied by the medical ventilator to the patient.

Abstract: A drug delivery apparatus includes a mouthpiece portion having an internal conduit for delivering an aerosol including the drug to the patient. The internal conduit has an inlet end and a mouthpiece end that is structured to be received in the patient's mouth. The mouthpiece portion is structured to operate at a substantially fixed inhalation flow rate when the patient inhales through the mouthpiece end. The apparatus further includes an aerosol generator for generating the aerosol from a drug supply and injecting the aerosol into a first region within the mouthpiece portion located between an outlet of the aerosol generator and the inlet end of the conduit. The mouthpiece portion also includes a flow accelerating mechanism that causes a localized flow rate at the first region to be greater than the inhalation flow rate. A method is also provided that increases the local flow rate within the mouthpiece portion.

Abstract: Embodiments of the invention provide a breathing mask for aircraft crewmember. The breathing mask includes an on-demand regulator with an inlet connected to a source of breathing gas and an outlet to exhaust the breathing gas. The outlet has an aperture controlled by a movable valve having an open position when the crewmember breathes out and a closed position when the crewmember breathes in. The breathing mask also has a latch member operable by a crewmember to latch the valve in the open position, the latch member including an unlocking member to release the valve when the cabin pressure is below a predetermined value.

Abstract: A mask system includes a mask component including one or more openings for gas washout and a vent component provided to the mask component. The vent component includes one or more tracks or grooves along its outer surface adapted to guide gas washout. The vent component is adapted to cover the one or more openings in the mask component so that gas washout escapes along the one or more tracks or grooves between an outer surface of the mask component and the vent component.

Abstract: A controlled discharge ostomy appliance assembly comprises (i) a stoma seal that is self-urging with a dynamic damping characteristic that resists changes of seal volume, (ii) a press-fit coupling member displaceable from an unlocked position to a locked position as part of a press-fit process, and (iii) a single-use frangible portion. The assembly further includes a protector shield removably fastened to the appliance forming a combined assembly therewith. The protector shield comprises (i) a seal displacer manipulable for displacing the stoma seal to a non-operative position ready for fitting, (ii) a substantially rigid coupling member guard portion for protecting the state of the coupling member, and (iii) a bracing portion for bracing the single-use frangible portion.

Abstract: A vaporizer system that supplies clean, heated air to vaporizable material by directing ambient air from an area surrounding the vaporizer system through a secure air passageway that leads the air through a pump, a heat source, and then onto the vaporizable material. The air passageway prevents the interaction of the air with possibly emissive components. The heated air drives out active ingredients from the vaporizable material, which may be subsequently captured in a removable container or inhaled directly. The vaporizer system includes an air chamber surrounding the receptacle for receiving the material to be vaporized which isolates the material from environmental disturbances. The removable container attaches to a valve, which attaches to the top of the vaporizer system. The valve is configured to be operable between three positions with the use of only one finger and a thumb of one hand.

Abstract: A liquid-collection canister includes a liquid collection chamber defined by at least one wall and a first and second gas-communication pathway formed within the at least one wall. A first aperture is positioned between the first gas-communication pathway and the liquid collection chamber to allow gaseous communication between the liquid collection chamber and the first gas-communication pathway. A second aperture is positioned between the second gas-communication pathway and the liquid collection chamber to allow gaseous communication between the liquid collection chamber and the second gas-communication pathway. A first and a second liquid-air separator are positioned over the first aperture and the second aperture, respectively, to substantially prevent liquid passing through the first and second apertures.

Abstract: A dry powder inhaler comprises at least one medicament reservoir and a closure member engaged with the reservoir so as to close an opening therein. A surface of the reservoir adjacent the opening and a surface of the closure member are in abutment, either directly or via a seal member interposed between the reservoir and the closure member. At least one abutting surface is formed with a projection that increases the contact pressure between said surfaces, thereby improving the seal between them and reducing the potential for ingress of moisture between said surfaces into the reservoir.

Abstract: A therapy system adapted to treat a patient's ventilatory instability using a ventilatory therapy, a gas modulation therapy, or both. The algorithm implemented by the therapy system monitors the ventilatory instability, such as Cheyne Stokes Respiration (CSR), mixed apneas, CPAP emergent apneas, and complex sleep disordered breathing (CSDB) and treats the ventilatory instability. The algorithm also determine a reference point with respect to the ventilatory instability. The therapy delivery system initiate the treatment based on the reference point.

Abstract: An attachment device (2) for use in the vacuum therapy of wounds has a vacuum-tight mounting element (6). A conduit is fastening to the upper side of that mounting element in a vacuum-tight manner. The conduit (4) communicates with the wound space through openings (22) in the mounting element (6) and in the vacuum dressing. The conduit (4) is flexible and flat and is connected to the mounting element (6) non-detachably and extensively in a longitudinal section (8) on the wound side over at least 70% of its surface projected perpendicularly onto the mounting means (6). The conduit (4) is made out of a flexible elastomer material of Shore A hardness of no more than 60 and the thickness (D) of the combined conduit (4) and mounting element (6) is no more than 7 mm.

Abstract: In various embodiments, a glaucoma shunt may include a tube having an anterior portion (with an opening) and a posterior portion. The glaucoma shunt may include a valve, inside the tube, coupled to a drainage portion. The tube may be configured to couple to a first portion of an eye and the drainage portion may be configured to couple to a second portion of the eye. In some embodiments, the drainage portion may be configured to move the valve relative to the tube such that when the eye expands, the valve moves away from the opening in the anterior portion of the tube to increase fluid flow. The drainage portion may further be configured to move the valve relative to the tube such that when the eye contracts, the valve moves toward the opening in the anterior portion of the tube to decrease fluid flow.

Abstract: The present application discloses devices and methods for delivering a therapeutic compound to the olfactory epithelium of an animal or human. The device having one or more channels for imparting a circumferential and axial velocity to the discharged fluid, and an outlet that discharges an aerosol spray having a circumferential and axial velocity as it enters the nasal cavity of a user. The device is designed to displace the air in the upper nasal cavity in order to specifically deposit a therapeutic agent on the olfactory epithelium while minimizing pressure and discomfort experienced by the user.

Abstract: An intraocular pressure control system for implantation in an eye of a patient to provide drainage from an anterior chamber of the eye to a drainage location at the eye includes a drainage tube and a valve system arranged to control drainage flow between the anterior chamber and the drainage site, the valve system being configured to control fluid flow using an electrolysis process and closed loop feedback from pressure sensors able to determine: flow rate, IOP, bleb pressure, and internal valve pressure.

Abstract: A gas mask and breathing equipment is provided with a circuit for breathing gas and with a heat exchanger (7) cooled by an evaporating agent. The evaporating agent is introduced from an evaporating agent container (8) into the heat exchanger (7) via at least one group of spraying elements (9) and a gas delivery means (11) allows a gas volume flow to flow through the heat exchanger (7).

Abstract: An inhalation device comprising a base having a slot for insertion of a single blister containing a dose of medicament to be inhaled into the base is disclosed. The inhaler has a mouthpiece pivotably mounted to the base which carries a blister piercing element operable to pierce a blister received in said slot when the mouthpiece is pivoted relative to the base. When a user inhales on the mouthpiece, the dose is entrained in an airflow and flows out of the blister through the mouthpiece and into the user's airway.

Abstract: A method for delivering ventilatory support to a patient is presented. The method includes controlling delivery of a first backup breath by delaying onset of the first backup breath, wherein delaying the onset of the first backup breath is configured to allow selection of an appropriate backup rate. Systems and computer-readable medium that afford functionality of the type defined by this method is also contemplated in conjunction with the present technique.

Abstract: A respiratory mask includes a mask frame and a forehead support provided to the mask frame. The forehead support includes a base extending from the frame. The base includes a flexible portion along at least a portion of its length including a material and/or physical characteristic that allows the base to flex from an original, unloaded position.

Abstract: Breathing assist kits having a cranio-cervical extension device and a strapless breathing mask are presented. The mask comprises a seal that couples the mask to a victim's face preferably using an adhesive gasket that ensures the mask does not become dislodged while a care giver provides assisted breathing. The mask can also include, among other enhancements, a window or a light gathering lens to provide a view into the victim's mouth.

Abstract: An airflow adaptor for a breath-actuated dry powder inhaler. The airflow adaptor includes a conduit having a proximal end and a distal end, wherein the proximal end allows fluid communication from a deagglomerator outlet port to the distal end of the conduit, and wherein the airflow adaptor further includes provisions for allowing air to flow from a proximal end of the adaptor to a distal end of the adaptor independently of the airflow in the conduit when a breath induced low pressure is applied to the distal end of the airflow adaptor.