Patent number: 7754711
Abstract: Methods of treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the methods comprise administering to a mammal in need thereof a compound of formula (Ia): where x, y, W, V, R2, R3, R4, R5, R6, R6a, R7, R7a, R8, R8a, R9 and R9a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Type:
Grant
Filed:
February 9, 2005
Date of Patent:
July 13, 2010
Assignee:
Xenon Pharmaceuticals Inc.
Inventors:
Nagasree Chakka, Mikhail Chafeev, Sultan Chowdhury, Jian-Min Fu, Duanjie Hou, Rajender Kamboj, Vishnumurthy Kodumuru, Shifeng Liu, Vandna Raina, Shaoyi Sun, Serguei Sviridov, Michael D. Winther, Zaihui Zhang, Melwyn Abreo, Mark W. Holladay, Wenbao Li, Sengen Sun, Chi Tu, Heinz W. Gschwend