Patents Examined by Mark L. Berck
  • 7,8-dihydroxy-1H-pyrazolo[3,4-f]quinoxalines
    Patent number: 5057516
    Abstract: Heterocyclic dihydroxyquinoxaline compounds having the formula ##STR1## wherein R.sup.2 is hydrogen, NO.sub.2, NH.sub.2, CN, halogen, or SO.sub.2 NH.sub.2 ;--X--Y--Z-- is selected from --NR.sup.3 --N=CR.sup.3 -- and --CR.sup.3 =N--NR.sup.3 --,wherein R.sup.3 is hydrogen, lower alkyl, or CF.sub.3.The invention also relates to a method of preparing the compounds, pharmaceutical compositions thereof, and their use.The compounds are useful in the treatment of indications caused by hyperactivity of the excitatory neurotransmitters.
    Type: Grant
    Filed: August 22, 1990
    Date of Patent: October 15, 1991
    Assignee: Novo Nordisk A/S
    Inventors: Poul Jacobsen, Flemming E. Nielsen, Tage Honore, Jorgen Drejer