Abstract: The present invention relates to nitric oxide donor compounds having a quinone based structure, to processes for their preparation and to their use in the treatment and/or prophylaxis of glaucoma and ocular hypertension.

Abstract: The invention disclosed herein relates to an enantioselective process for preparation of biologically active (R) and (S) enantiomers of sex pheromones of the long-tailed Mealybug with high enantiopurity having significant biological activity. Further, the invention provides absolute configuration of synthesized R and S enantiomers.

Abstract: A process for preparing a reverse osmosis membrane that includes: (A) providing a polyamine, a polyfunctional acid halide, and a flux increasing additive having the formula Z+B?, where Z+ is an easily dissociable cation and B? is a beta-diketonate; (B) combining the polyamine, polyfunctional acid halide, and flux increasing additive on the surface of a porous support membrane; and (C) interfacially polymerizing the polyamine and the polyfunctional acid halide, and flux increasing additive on the surface of the porous support membrane to form a reverse osmosis membrane comprising (i) the porous support membrane and (ii) a discrimination layer comprising a polyamide. The reverse osmosis membrane is characterized by a flux that is greater than the flux of the same membrane prepared in the absence of the flux increasing additive.

Abstract: The present invention provides an alkali metal salt of fluorosulfonyl imide having favorable heat resistance and a reduced content of specific impurities and a water content, and provides a method for producing an alkali metal salt of fluorosulfonyl imide, which is capable of easily removing a solvent from a reaction solution. An alkali metal salt of fluorosulfonyl imide of the present invention is represented by the following general formula (I) and has a mass loss rate of 2% or less when the alkali metal salt of fluorosulfonyl imide is kept at 100° C. for 8 hours under an air current. A method for producing an alkali metal salt of fluorosulfonyl imide of the present invention comprises a step of concentrating a solution of the alkali metal salt of fluorosulfonyl imide by bubbling a gas into a reaction solution containing the alkali metal salt of fluorosulfonyl imide, and/or concentrating a solution of the alkali metal salt of fluorosulfonyl imide by thin layer distillation.

Abstract: Resin compositions, layers, and interlayers comprising two or more thermoplastic polymers and at least one RI balancing agent for adjusting the refractive index of at least one of the resins or layers is provided. Such compositions, layers, and interlayers exhibit enhanced optical properties while retaining other properties, such as impact resistance and acoustic performance.

Abstract: The present invention provides a pest control agent, acaricide or fungicide that contains, as the active ingredient thereof, at least one type of compound selected from the aryloxyurea compounds represented by formula (V) (wherein R1 to R5 each independently represents an alkyl group or the like, X is a halogen atom or the like, n is an integer of 0 to 5, and Z is an oxygen atom or sulfur atom) or salts thereof.

Abstract: A catalyst composition comprises (i) a support; (ii) a dehydrogenation component comprising at least one metal or compound thereof selected from Groups 6 to 10 of the Periodic Table of Elements; and (iii) tin or a tin compound, wherein the tin is present in an amount of 0.01 wt % to about 0.25 wt %, the wt % based upon the total weight of the catalyst composition.

Abstract: The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof, comprising a drug linker conjugate D-L, wherein D being a biologically active moiety containing an aromatic hydroxyl group is conjugated to one or more polymeric carriers via secondary carbamate-containing linkers L. Such carrier-linked prodrugs achieve drug releases with therapeutically useful half-lives. The invention also relates to pharmaceutical compositions comprising said prodrugs and their use as medicaments.

Abstract: The present invention relates to prodrugs or a pharmaceutically acceptable salt thereof comprising a covalent treprostinil carrier conjugate as well as pharmaceutical composition comprising said compounds. The compounds may be used as medicaments, especially for diseases or disorders which can be treated by treprostinil, such as pulmonary arterial hypertension (PAH).

Abstract: Process for the preparation of lipophilic polyalkylenepolyamines by homogeneously catalyzed alcohol amination, where aliphatic amino alcohols are reacted with one another or aliphatic diamines or polyamines are reacted with aliphatic diols or polyols with the elimination of water in the presence of a homogeneous catalyst, at least one of the reactants comprising an alkyl or alkylene group having five or more carbon atoms, and after the reaction a phase separation into at least one apolar phase and at least one polar phase being present, the lipophilic polyalkylenepolyamines being present in enriched form in the apolar phase. Polyalkylenepolyamines obtainable by such processes, and polyalkylenepolyamines comprising hydroxyl groups, secondary amines or tertiary amines.

Abstract: A simple, commercially viable process for the preparation of phosphonic acid monomers containing essentially no diester or inorganic phosphorous acid compounds is disclosed.

Abstract: Disclosed are a novel organic compound and an organic light emitting diode device using the same. More particularly, a novel organic compound having electrical stability, high charge transport capability, and light emitting performance, high glass transition temperature and being capable of preventing crystallization, and an organic light emitting diode device including an organic layer including the same are disclosed.

Abstract: A method for synthesizing ammonia borane includes (a) preparing a reaction mixture in one or more solvents, the reaction mixture containing sodium borohydride, at least one ammonium salt, and ammonia; and (b) incubating the reaction mixture at temperatures between about 0° C. to about room temperature in an ambient air environment under conditions sufficient to form ammonia borane. Methods for synthesizing ethylenediamine bisborane, and methods for dehydrogenation of ethylenediamine bisborane are also described.

Abstract: [6,6]-Phenyl C71 butyric acid derivatives (C70-PCBR3) having a selectivity of greater than 95 wt % of the ?-isomer are provided by reacting fullerene C70 with a dialkyl sulfonium tetrafluoroborate having the formula:

Abstract: Process for treating a zeolite catalyst for the carbonylation of dimethyl ether to produce methyl acetate, in which the catalyst is contacted with a treatment gas containing water vapor in an amount of at least 1 mol % and at a temperature below which dealumination of the zeolite structure occurs. The zeolite contains at least one channel which is defined by an 8-member ring and is mordenite.

Abstract: The present invention provides a method for producing (meth)acrylic acid, which achieves enhanced productivity or a reduced amount of a catalyst in production of (meth)acrylic acid from 3-hydroxycarboxylic acid, and enables stable production of (meth)acrylic acid at low cost. The method is a method for producing (meth)acrylic acid using 3-hydroxycarboxylic acid as a starting material, the method including a polymerization step of polymerizing 3-hydroxycarboxylic acid to generate a composition containing a 3-hydroxycarboxylic acid polymer, and a step of generating (meth)acrylic acid from the composition containing the 3-hydroxycarboxylic acid polymer, the 3-hydroxycarboxylic acid polymer obtained in the polymerization step including trimer or higher order units, the trimer or higher order units constituting 3% by mass or more of a total of 100% by mass of the 3-hydroxycarboxylic acid and the 3-hydroxycarboxylic acid polymer.

Abstract: The present invention relates to a method for producing a hydride having a carbon number of 4, comprising contacting, in liquid phase, an unsaturated compound having a carbon number of 4 as a raw material with a solid catalyst obtained by loading a metal element belonging to Groups 9 to 11 of the long periodic table on a support, thereby performing hydrogenation to produce a corresponding hydride having a carbon number of 4, wherein hydrogenation is performed in the presence of, as a solvent, a 1,4-butanediol having a nitrogen component concentration of 1 ppm by weight to 1 wt % in terms of nitrogen atom.

Abstract: Disclosed is a method for treating or using offgases obtained in a melamine plant comprising at least one melamine synthesis reactor and at least one washing unit in an integrated process for urea and melamine production, wherein the offgases leaving the melamine synthesis reactor are fed into the washing section and the washed offgases leaving the washing section are transferred from the washing section via at least one pipeline connecting the washing section and the at least one urea synthesis plant to the at least one urea synthesis plant. The washed offgases leaving the washing section are mixed with at least one carbamate solution immediately downstream of the washing section by feeding the carbamate solution into the pipeline connecting the washing section to the urea plant.

Abstract: Methods and systems for producing high purity 3-hydroxypropionic acid (3-HP) from an aqueous medium, such as a fermentation broth, are described. Aqueous 3-HP solution can be purified by flash evaporation wherein the 3-HP is vaporized at an elevated temperature without conversion to acrylic acid. This process can be integrated with downstream processes for producing other chemical and consumer products.

Abstract: There is provided is a method for making a higher purity alcohol comprising: a) contacting an impure alcohol composition comprising: (i) an alcohol compound; and (ii) from about 50 ppm to about 5 weight percent, based on the weight of the impure alcohol composition, of at least one hydrogenable contaminant having an unsaturated bond, with hydrogen in a hydrogenation reactor and in the presence of a hydrogenation catalyst to produce a reaction mixture comprising the alcohol compound and a hydrogenated contaminant product wherein at least 10 mole % of the at least one hydrogenable contaminant in the reaction mixture is converted; and b) separating the alcohol compound from at least a portion of the reaction mixture to produce an enriched alcohol composition having a lower concentration of the hydrogenated contaminant product. There is also provided an alcohol composition having less than about 500 ppm of at least one hydrogenable contaminant.