Abstract: A stent attachment and deployment mechanism is utilized to prevent the distal end of an endoprosthesis comprising fixation barbs or other fixation mechanism from deploying prior to the remaining sections of the fixation device. With this stent attachment and deployment mechanism accurate deployment may be achieved.

Abstract: A colpotomy system includes a surgical instrument having a cutting element and a receiver at a distal end thereof and a uterine instrument. The uterine instrument has a handle operably coupled to a shaft having a balloon at a distal end thereof, the shaft extending through a retaining member to access a surgical site, the retaining member including a plurality of transmitters for transmitting at least one signal. A distance between the cutting element of the surgical instrument and one end of the retaining member of the uterine instrument is calculated to determine whether the cutting element is within a predetermined operating zone.

Abstract: A medical device includes a sheath, an shaft at least partially surrounded by the sheath, an end effector at a distal end of the shaft and movable between at least an open position and a closed position, and a handle. The handle includes a shaft advancement body, a channel body securely coupled to the sheath and selectively positionable with respect to the shaft advancement body, and a plunger securely coupled to the shaft and selectively positionable with respect to the channel body.

Abstract: An improved left atrial appendage (LAA) occluder is provided. The improved LAA occluder includes a sealing disc and an anchoring device, both of which are mutually connected, At least two flow blocking membranes are arranged in the sealing disc. A part, cooperating with an LAA, of the anchoring device is an anchoring net, and the anchoring net is of a backboneless structure. The whole anchoring device is of the backboneless structure. The anchoring device is formed by weaving metal wires, a distal end of the anchoring device is opened, a proximal end of the anchoring device is constricted and is connected with the sealing disc to form a conical net, the distal end of the anchoring device is opened and is rolled towards the proximal end to form the anchoring net, and the anchoring net surrounds the conical net.

Abstract: An anchor bolt fixation system for catheter probes and electrodes having different diameters. A removable reducing tube is provided for insertion into the lumen of an anchor bolt and an anchor bolt cap is provided for securing the reducing tube to the anchor bolt. A second anchor bolt cap is provided having a bore with a diameter generally equal the diameter of the lumen of the reducing tube.

Abstract: Methods, devices and systems for delivering a device assembly into a gastric or other space within the body, allowing the device to expand to occupy volume within the gastric space and, after an effective period of time, delivering a substance or stimulus to begin breakdown of the expanded device so that it may release from the body.

Abstract: The present embodiments provide an endoluminal prosthesis deployment system and method for deploying the prosthesis for cannulation of branch vessels. The prosthesis includes an anterior fenestration and a posterior opening. A guide is disposed to exit the prosthesis lumen through a lateral fenestration, enter through the anterior fenestration, and exit the prosthesis lumen through the posterior opening. A sheath can be preloaded over the branch wire at the lateral fenestration for vessel cannulation, such as in renal arteries. The sheath can include another branch wire that extends from the lateral fenestration to another lateral fenestration. An end of the guide is retracted after partial expansion of the prosthesis, and another sheath is inserted over the retracted guide and moved through the posterior opening and to the anterior fenestration. A separate branch guide wire is then directed through the sheath for vessel cannulation, such as the SMA.

Abstract: A needlescopic scissors end effector assembly includes a pair of jaws or blades pivotable to perform a cutting or shearing operation. The scissors end effector assembly includes a cannula having a diameter between about 1 mm to 5 mm and a needle tip configured for percutaneous operation. The pair of jaws or blades includes cam profile surfaces to interact with an opening defined with the needle tip to actuate opening and closing of the pair of jaws or blades and to prevent backlash effect during the opening and closing of the pair of jaws or blades.

Abstract: The present invention relates to a tissue protection device for mitral valve cerclage annuloplasty and, more particularly to a tissue protection device for protecting tissues of the body (heart) during mitral valve cerclage annuloplasty that is performed on a mitral valve cerclage patient with mitral regurgitation. The tissue protection device for mitral valve cerclage annuloplasty of the present invention is a hollow cylindrical tube where cerclage sutures (10a, 10b) are inserted, in which a hole (22) is formed at a predetermined portion of the cylindrical tube so that a coronary sinus cerclage suture (10a) inserted in a coronary sinus comes out of the cylindrical tube, and a lower section from the hole is inserted into the tricuspid valve to protect tissues of the tricuspid valve and the ventricular septum.

Abstract: Methods, devices and systems for delivering a device assembly into a gastric or other space within the body, allowing the device to expand to occupy volume within the gastric space and, after an effective period of time, delivering a substance or stimulus to begin breakdown of the expanded device so that it may release from the body.

Abstract: An instrument comprises a flexible body comprising a proximal portion, a distal portion, and an inner sheath within the proximal portion. The inner sheath comprises a wall and a plurality of conduits extending through the wall within the proximal portion. A distal end of each conduit terminates proximal to the distal portion. The inner sheath further comprises a plurality of protrusions within the proximal portion. Each protrusion surrounds a portion of a corresponding conduit. The flexible body further comprises a steerable tube extending within the distal portion. The steerable tube comprises a wall and a plurality of grooves in the wall. The instrument further comprises a plurality of tendons extending from the proximal portion, beyond the distal ends of the plurality of conduits, and into the distal portion. In the proximal portion, each tendon extends through a corresponding conduit. In the distal portion, each tendon extends within a corresponding groove.

Abstract: A dual-directional, or multi-degree-of-freedom, surgical clip is provided. The clip includes a top clamp. A bottom clamp is hingedly connected to the top clamp at a hinged joint for mutually pivotal transverse motion about the hinged joint. The top and bottom clamps each include a hinged attachment at an extreme end thereof. A first portion of each of the top and bottom clamps is in hinged connection with a corresponding second portion of the respective top and bottom clamps for mutually pivotal lateral movement. A method of using the clip to concurrently grasp and move patient tissue is also provided.

Abstract: Medical device for transcatheter heart valve repair comprising a grasping tweezer (1) and a plicating tweezer (2), said grasping tweezer (1) being adapted to grasp a leaflet rim (3) and said plicating tweezer (2) comprising two rotatable flaps (4,5) and a central shaft (6) around which said flaps (4,5) may rotate in a “butterfly manner”, in such a way that the plicating tweezer (2) may adopt a closed or an open configuration. The invention also relates to a method for using this medical device.

Abstract: A method of stapling tissue is disclosed. The method can include obtaining a staple cartridge including a plurality of staples, wherein each staple has a base and a leg extending from the base. The stapling method can also include firing the staples from the staple cartridge, wherein the staples are fired into tissue in a staple line. The staple line can include a first portion having a first flexibility and a second portion having a second flexibility, wherein the second flexibility is different than the first flexibility. A method of stapling tissue can also include adapting an anvil with an anvil plate having an arrangement of staple-forming pockets that differs from the staple-forming pockets in the anvil.

Abstract: A suturing device includes a clamshell body having a first side coupled to a second side by a hinge. The first side and the second side each have an end opposite the hinge. A spool is coupled to the clamshell body and rotatable relative to the clamshell body. A suture is wound around the spool. The ends of the first side and the second side may lock together to capture an end of the suture.

Abstract: A device for occluding a vasculature of a patient including a micrograft having an absorbent polymeric structure with a lumen of transporting blood. The micrograft has a series of peaks and valleys formed by crimping. The occluding device is sufficiently small and flexible to be tracked on a guidewire and/or pushed through a microcatheter to a site within the vasculature of the patient. Delivery systems for delivering the micrografts are also disclosed.

Abstract: A delivery device for a collapsible medical device may include a handle and a delivery assembly having a compartment for receiving the medical device. A catheter member may extend from the handle to the delivery assembly. The catheter member may have a first portion with a first compliance value and a second portion with a second compliance value different from the first compliance value. An internally threaded member may be fixedly connected to the delivery assembly. An externally threaded member may have a first portion operatively connected to the actuation member and a second portion threadedly coupled to the internally threaded member so that manipulation of the actuation member causes axial movement of the compartment relative to the catheter member.

Abstract: A method for the hemostasis of perforating and bleeding vessel related to intracerebral hemorrhage (ICH) includes navigating an occlusion device into a parent artery and then deploying the occlusive device to transiently occlude bleeding vessels to reduce blood flow and local blood pressure until hemostasis is achieved, while maintaining flow within the parent artery. Embodiments of the occlusion device include a catheter, an expandable member sized for insertion into the mid-cerebral artery (MCA) and having a length sufficient to occlude at least one ostia of the lenticulostriate arteries (LSA), with a flow path for blood provided from a proximal side of the expandable member to a distal side of the expandable member, and a semi-permeable contacting member about the expandable member and adapted to be in contact with a wall of the MCA adjacent the ostia, the semi-permeable member permitting a reduce flow of blood through the ostia.

Abstract: The maxillary frenum clamping tool includes two articulating members, each of the members having a clamping end and a gripping end. The clamping ends of the articulating members are curved to retract the upper lip while clamping the maxillary labial frenum and have blunt tips to minimize damage to the surrounding tissue. Immediately below the blunt tips, each member defines a jaw section having a serrated inner edge. The outer edges of the jaw sections define guide indentations for guiding a curved suture needle. The gripping end of each member defines a finger loop and part of a ratcheting lock mechanism for locking the members at set positions. During use, the clamping too may be used to clamp the maxillary frenum with the jaw portions so that the clamped tissue can be easily sutured using the guide indentations.

Abstract: An embodiment includes a uterine manipulator system comprising: a collar including a first shelf connected to the inner surface of the collar; a stabilizer including a stabilizer rim adapted to couple to the first shelf; and a shaft adapted to pass through the stabilizer and a hollow tunnel of the collar with a bulbous tip. Other embodiments are described herein.