Patents Examined by Maryam Monshipoouri
  • Tethered function assay for protein function
    Patent number: 5985575
    Abstract: A method for determining the function of a test protein is disclosed. In a preferred embodiment, this method comprises the steps of fusing a test protein to an RNA-binding protein and exposing the fusion protein to recombinant reporter mRNA molecule that comprises a binding site for the RNA-binding protein in the 3' untranslated region. One then observes the properties of reporter mRNA and correlates the reporter properties with test protein function.
    Type: Grant
    Filed: May 20, 1998
    Date of Patent: November 16, 1999
    Assignees: Wisconsin Alumni Research Foundation, The Arizona Board of Regents on behalf of the University of Arizona
    Inventors: Marvin P. Wickens, Roy Parker