Patents Examined by Matthew A Engel
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Patent number: 10342917Abstract: Infusion fluid is flowed through a fluid delivery line of an infusion system. Optical signals having different wavelengths are transmitted through the fluid delivery line. The transmitted optical signals having the different wavelengths are received. At least one processor determines whether air or infusion fluid is disposed in the fluid delivery line based on the received optical signals having the different wavelengths.Type: GrantFiled: February 27, 2015Date of Patent: July 9, 2019Assignee: ICU Medical, Inc.Inventors: Gary David Shubinsky, Tamas Ban, Brian G. Markey
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Patent number: 10342706Abstract: Disclosed are compositions that comprise an organic electrochemical mediator and a gasotransmitter salt which converts into a gasotransmitter via electron transfer. Also disclosed are bandages and wound dressings comprising the subject gasotransmitters, and methods of making a gasotransmitters, comprising exposing the compositions to a voltage sufficient to reduce the water soluble organic mediator. Further disclosed are methods of treating a variety of trauma and disease states by applying a therapeutically effective amount of at least one gasotransmitter thereto, and methods of generating an effective dose of the gasotransmitter generated from electrolytic reaction involving the gasotransmitter-generating compositions.Type: GrantFiled: January 18, 2018Date of Patent: July 9, 2019Assignee: Noxsano Inc.Inventors: Alan Willey, Stevan Samuel
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Patent number: 10335550Abstract: A pharmaceutical injection device includes a main body case, a cartridge holder, a latching receiver, a driver, and a manipulation component. The cartridge holder has a holding space and a holder latching component. The holding space is capable of holding a pharmaceutical cartridge. The latching receiver is configured to latch or release the holder latching component according to whether the cartridge holder is closed or open. The driver is configured to automatically release a latching of the latching receiver and the holder latching component. The manipulation component is configured to manually release the latching of the latching receiver and the holder latching component by moving the latching receiver upon being subjected to external pressure. The driver or the manipulation component is configured to release the latching between the latching receiver and the holder latching component.Type: GrantFiled: March 3, 2015Date of Patent: July 2, 2019Assignee: PHC HOLDINGS CORPORATIONInventors: Kenji Murakami, Masato Kagiyama, Takeshi Imada, Tooru Aoki
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Patent number: 10335554Abstract: A single-use cover assembly that obscures a substantial majority or an entirety of an injection needle from view before, during, and after an injection procedure. The cover assembly includes a housing and a needle sleeve that retracts and extends by sliding axially within the housing. The needle sleeve carries a locking collar that moves from a first position to a second position once the needle sleeve is fully retracted. In the first position the locking collar allows retraction of the needle sleeve from a fully extended position. In the second position, a portion of the locking collar covers a tip of the needle, thereby preventing retraction of the needle sleeve from the fully extended position.Type: GrantFiled: June 24, 2013Date of Patent: July 2, 2019Assignee: Sta-Med, LLCInventors: Sergio Rubinstein, Samuel Kanosky Rosenberg, Russell R. Stepke, Richard Mazursky, Todd Herlitz, Josh Harker, Mark W. Godfrey, Stephen M. Jokela
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Patent number: 10335538Abstract: A treatment method that increases circulation and pluripotency of stem and progenitor cells within a patient can be used to fight off or cure various diseases for the patient such as chronic kidney disease or end-stage renal disease. An administrator of the treatment method is provided with a medicinal-administration system such as an intravenous injection system. The treatment method begins by preparing a dosage of oxygen-ozone mixture with the medicinal-administration system. The medicinal-administration system then transfuses the oxygen-ozone mixture in the patient's bloodstream so that the renal system and/or the bone marrow can be targeted by the oxygen-ozone mixture. These steps are repeated as a plurality of treatment session for the patient.Type: GrantFiled: January 23, 2017Date of Patent: July 2, 2019Inventor: Priya Visweswaran Balakrishnan
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Patent number: 10322229Abstract: An infusion pump assembly includes a reservoir assembly configured to contain an infusible fluid. A motor assembly is configured to act upon the reservoir assembly and dispense at least a portion of the infusible fluid contained within the reservoir assembly. Processing logic is configured to control the motor assembly. The processing logic includes a primary microprocessor configured to execute one or more primary applications written in a first computer language; and a safety microprocessor configured to execute one or more safety applications written in a second computer language.Type: GrantFiled: December 19, 2016Date of Patent: June 18, 2019Assignee: DEKA PRODUCTS LIMITED PARTNERSHIPInventors: Geoffrey P. Spencer, Robert J. Bryant
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Patent number: 10315007Abstract: A vascular access system includes a catheter having an inner lumen in communication with an open distal end; a guidewire at least partially positioned in the catheter lumen and extending out the open distal end thereof, respective proximal and distal stops secured to the guidewire; and a centering device slidably mounted on the guidewire such that the centering device may freely within the catheter lumen relative to the guidewire between the proximal and distal stops, wherein the centering device substantially aligns a longitudinal axis of the catheter with a longitudinal axis of the guidewire proximate the centering device.Type: GrantFiled: July 14, 2015Date of Patent: June 11, 2019Assignees: Stryker Corporation, Stryker European Holdings I, LLCInventors: Jason Chan, Huey Chan
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Patent number: 10307094Abstract: A microperfusion needle or fistula needle with a protective element comprises a first component comprising a cannula, a body rigidly joined to the cannula, and having grasping wings extending therefrom, a second component comprising an elongate body having a cavity for slidably receiving the first component between an operating position of the cannula and a safety position of the cannula, the elongate body having lateral slots for the grasping wings to extend therethrough, the grasping wings being suitable for elastically bending around and contacting opposed portions of the elongate body. The elongate body comprises two arrays of projections, which are contacted by the wings when bent. Opposed pairs of projections are designed to contact and mechanically interfere with the grasping wings when bent.Type: GrantFiled: July 6, 2016Date of Patent: June 4, 2019Assignee: PIKDARE S.R.L.Inventors: Elena Mauri, Pierluigi Franco, Daniele Pollaci
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Patent number: 10307289Abstract: A subcutaneous implant system is applicable in a variety of surgical procedures and includes a balloon shaped implant formed from a bioresorbable material and is capable of assuming deflated and inflated configurations. The balloon shaped implant is inserted, in its deflated configuration, into the patient's body, and subsequently is inflated by filling the balloon shaped implant with a medicinal agent. The balloon shaped implant filled with the medicinal agent remains in the body and permits a steady-state release of the medicinal agent therefrom. The balloon shaped implant has a wall which may be formed from either a solid material which is impermeable to the medicinal agent, or a porous material. The medicinal agent egresses from the interior of the balloon shaped member in a controlled manner provided by a mechanism which may include a permeable membrane, a check valve, a flap valve, openings in a porous wall of the balloon shaped member, and combinations thereof.Type: GrantFiled: July 28, 2017Date of Patent: June 4, 2019Assignee: Drug Delivery Company, LLCInventors: Jeffrey D. Benner, Steven M. Cohen, Christopher Forrest Lumpkin
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Patent number: 10307539Abstract: A medicament delivery device includes a generally elongated tubular housing having opposite proximal and distal parts; a needle shield sleeve slidably and coaxially arranged inside the housing with a proximal part of the sleeve protruding a distance outside the proximal part of the housing; a syringe carrier mechanism having a syringe carrier slidably and coaxially arranged within the needle shield sleeve, a syringe having a stopper, a medicament, and a needle, the syringe being coaxially arranged within the syringe carrier; and a holding member connected to the syringe carrier; a first activator member an a second activator member; a drive mechanism adapted to accumulate a drive force for moving the syringe carrier mechanism in a first step and a second step. The second activator member is arranged within an information device for producing audible, visual, and/or tactile feedback to a user about a completed injection.Type: GrantFiled: October 6, 2016Date of Patent: June 4, 2019Assignee: SHL Medical AGInventor: Oscar Alexandersson
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Patent number: 10293119Abstract: The technical problem of the present invention to provide a medical device, which exhibits an increased safety of the device and facilitates a safe use is solved by medical device for delivering at least one drug agent, comprising a sensor, a control unit and an attachable dispense assembly, wherein the sensor is configured to detect attachment of the dispense assembly to the medical device, wherein the control unit is configured to determine at least based on a signal from the sensor whether the end of life of the dispense assembly is reached and wherein the medical device is configured to indicate the end of life of the dispense assembly. The technical problem is further solved by a method according to the invention.Type: GrantFiled: January 31, 2013Date of Patent: May 21, 2019Assignee: Sanofi-Aventis Deutschland GmbHInventors: Michael Caspers, Ilona Eggert
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Patent number: 10279121Abstract: A mixing device and a retractable syringe comprising same are provided. The mixing device comprises concentric outer and inner barrels that form an outer chamber, the inner barrel having an inner chamber. A mixing plunger is slidably located in the outer chamber. A seal located in the outer chamber is capable of axial movement, in response to depression of the mixing plunger, from a first position in sealing engagement with one or more apertures in the inner barrel to a second position intermediate the apertures and vents in the outer barrel. This allows depression of the mixing plunger to force a first substance from the outer chamber through the apertures to mix with a second substance in the inner chamber. The mixed substance in the inner barrel is then delivered by the syringe with subsequent needle retraction.Type: GrantFiled: October 22, 2015Date of Patent: May 7, 2019Assignee: UNL Holdings LLCInventors: Ramin Mojdehbakhsh, Peter J. Dungar, Ashley W. Palmer, Robert E. Johannesson, Philip A. Weaver, Aaron M. Weir
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Patent number: 10279155Abstract: A system and method for delivering a bathing liquid via a nostril of a face-down user maintains the liquid in prolonged and predictable contact with the nasal and sinus mucosa. A head orientation unit attaches to the head and includes an angle monitoring unit to provide an indication of the angular orientation of the head as it turns to optimize delivery of the liquid to target head structures. A liquid supply delivers the liquid through the user's nostrils to the selected head structures as a function of the angular orientation indication and at a pressure and flow rate that maintains a constant volume of liquid in the nasal and sinus cavities. Indicia on the angle monitoring unit permit the user to orient his/her head to predetermined angular positions.Type: GrantFiled: November 4, 2013Date of Patent: May 7, 2019Inventor: Michael B. Siegel
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Patent number: 10272196Abstract: Ambulatory infusion pumps, pump assemblies, cartridges, baseplates, cannulas, insertion tools, and related components as well as combinations thereof and related methods.Type: GrantFiled: December 22, 2014Date of Patent: April 30, 2019Assignee: perQflo, LLCInventors: Roger E. Smith, James Causey, Scott R. Gibson
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Patent number: 10265116Abstract: The invention relates to a device, preferably a collar, for treating areas of human or animal skin or mucous membrane with a cold atmospheric pressure plasma by creating a dielectrically hindered surface discharge, comprising at least one flexible insulating material (1), a flexible high-voltage electrode (2), a flexible dielectric (3), a flexible grounded electrode (4) and a gas supply (7), characterized in that the flexible high-voltage electrode (2) is embedded in the insulating elastomer (3), having the effect of a dielectric, and the grounded electrode (4) is applied to the elastomer surface facing the surface to be treated.Type: GrantFiled: June 5, 2015Date of Patent: April 23, 2019Assignee: LEIBNIZ-INSTITUT FUER PLASMAFORSCHUNG UND TECHNOLOGIE E.VInventors: Manfred Stieber, Klaus-Dieter Weltmann, Stefan Horn, Ronny Brandenburg, Thomas Von Woedtke
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Patent number: 10258784Abstract: A device for reducing agent penetration at an insertion site is provided that has a porous inner sleeve fluidly connected to a conduit. A vacuum or hydrodynamic source is fluidly connected to the conduit. The device is stabilized by fibroblast in-growth and inhibits bacterial colonization. A device is also provided that has a conduit having a bore and an outer conduit surface. The outer conduit surface is optionally nanotextured to promote fibroblast adhesion and limit bacterial residency. A sleeve is provided in fluid communication with the bore of the conduit, and is formed from materials characterized by a pore matrix through which vacuum or hydrodynamic draw is achieved in a process to promote stabilization and reducing bacterial colonization by draw fluid from an area around the surrounding the site of the device. The sleeve optionally has a distal nanotextured surface.Type: GrantFiled: March 9, 2012Date of Patent: April 16, 2019Assignee: Viaderm LLCInventors: Allen B. Kantrowitz, Chris Mortin, Daniel C. Wadsworth, Jr.
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Patent number: 10231869Abstract: The present invention is an intraocular surgery system using a Venturi pump and capable of preventing clogging due to nucleus fragments, despite a reduced aspiration flow rate.Type: GrantFiled: February 27, 2015Date of Patent: March 19, 2019Assignees: SENJU PHARMACEUTICAL CO., LTD., KISHIMOTO, MAKOTOInventor: Makoto Kishimoto
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Patent number: 10232123Abstract: An injected dose detection device including a housing having a joint surface surrounding an injection device, a vibration sensor disposed in an internal part of the housing configured to detect at least one vibration signal of a dose-setting action based on a minimum vibration threshold, an acoustic sensor disposed in the internal part of the housing configured to detect at least one dosage click of the dose-setting action, a vibration transmitting element positioned directly between the vibration sensor and the injection device and configured to transmit the at least one vibration signal and a processing unit configured to process the at least one vibration signal from the dose-setting action and the at least one dosage click from the dose-setting action for generating set dose information corresponding to the injected dose wherein a bottom plate and a side wall of the vibration transmitting element form a shell structure to cover the vibration sensor.Type: GrantFiled: February 13, 2018Date of Patent: March 19, 2019Assignee: INNOVATIVE PRECISION INSTRUMENTS LIMITEDInventor: Richard Jean Marie Binier
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Patent number: 10232140Abstract: A support device for preventing an occlusion of a catheter's root region including an extended, flexible member extending from an end of a catheter adapter. The flexible extension is tapered such that additional support is provided to the portions of the root region most susceptible to an occlusion. Additionally, the flexible extension provides shielding to the root region thereby preventing contamination of the same. Finally, the flexible extension provides a marking function whereby the technician may insert the catheter tube until such a point that the flexible extension contacts the patient thereby preventing over insertion of the catheter tube.Type: GrantFiled: December 18, 2007Date of Patent: March 19, 2019Assignee: BECTON, DICKINSON AND COMPANYInventor: Austin Jason McKinnon
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Patent number: 10232122Abstract: A drive mechanism for a drug delivery device, preferably for a pen-type injector, the mechanism comprises a spindle (6) movable in a first direction during a delivery step, a splined portion (5, 11) operatively coupled to the spindle (6), and retraction means (12, 15, 16, 17, 20) acting on the splined portion (5, 11) at least at the end of the delivery step. Thereby, that after the delivery step the spindle (6) and/or the splined portion (5, 11) is moved in a second direction contrary to the first direction, such that the whole drive mechanism is relieved from stresses.Type: GrantFiled: September 3, 2010Date of Patent: March 19, 2019Assignee: Sanofi-Aventis Deutschland GMBHInventors: Michael Jugl, Gunther Sendatzki, Axel Teucher