Patents Examined by Matthew Keogh
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Patent number: 8927806Abstract: The present invention relates to the isolation, purification, characterization and use of the plant Snf1-related protein kinase (SnRK) gene and genetic products. The invention includes isolated and purified SnRK DNA and relates to methods of regulating water loss and plant drought tolerance, sucrose content, starch content, seed oil content, fatty acid synthesis, seed oil acyl composition, seed size/weight, resistance/tolerance to biotic stresses, increased root biomass, and/or carbon flux into other seed components, plant, using the gene, and to tissues and plants transformed with the gene. The invention also relates to transgenic plants, plant tissues and plant seeds having a genome containing an introduced DNA sequence of the invention, and a method of producing such plants and plant seeds.Type: GrantFiled: April 9, 2010Date of Patent: January 6, 2015Assignee: DowAgroSciences, LLCInventors: Zhifu Zheng, Thomas W. Greene
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Patent number: 8921652Abstract: The specification relates to plants and their seeds and oil obtained therefrom, and to methods of producing same comprising oil having modified fatty acid compositions, such that 28% to 80% of the total fatty acid content in the seedoil is palmitic acid, 0% to 16% is palmitoleic acid, 0% to 4% is C16:2 fatty acid, 3% to 33% is stearic acid, 1% to 40% is oleic acid, 4% to 50% is linoleic acid and 0% to 10% is linolenic acid. The specification describes nucleic acid molecules encoding RNA capable of conferring these properties, in particular, RNA that inhibits expression of an oil biosynthesis gene encoding KASII in seeds of a plant. Genetic constructs and cells comprising the nucleic acid molecules are also described and claimed.Type: GrantFiled: January 21, 2011Date of Patent: December 30, 2014Assignee: Commonwealth Scientific and Industrial Research OrganisationInventors: Qing Liu, Allan Graham Green, Surinder Pal Singh
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Patent number: 8921112Abstract: Disclosed herein are zinc fingers comprising CCHC zinc coordinating residues. Also described are zinc finger proteins and fusion proteins comprising these CCHC zinc fingers as well as polynucleotides encoding these proteins. Methods of using these proteins for gene editing and gene regulation are also described.Type: GrantFiled: October 1, 2008Date of Patent: December 30, 2014Assignees: Dow AgroSciences LLC, Sangamo BioSciences, Inc.Inventors: Qihua C. Cai, Vipula K. Shukla, Joseph F. Petolino, Lisa W. Baker, Robbi J. Garrison, Ryan C. Blue, Jon C. Mitchell, Nicole L. Arnold, Sarah E. Worden, Jeffrey Miller, Fyodor Urnov
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Patent number: 8912392Abstract: Methods and compositions for altering the genome of a monocot plant cell, and a monocot plant are disclosed. The methods and compositions use a double-strand break inducing agent to alter a monocot plant or plant cell genomic sequence comprising a recognition sequence for the double-strand break inducing agent.Type: GrantFiled: June 27, 2008Date of Patent: December 16, 2014Assignee: Pioneer Hi-Bred International, Inc.Inventors: L. Aleksander Lyznik, Yumin Tao, Huirong Gao
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Patent number: 8901374Abstract: The invention provides isolated nucleic acid molecules which encode novel fatty acid dehydratase family members. The invention also provides recombinant expression vectors containing dehydratase nucleic acid molecules, host cells into which the expression vectors have been introduced, and methods for large-scale production of long chain polyunsaturated fatty acids (LCPUFAs), e.g., SDA, EPA and DHA.Type: GrantFiled: June 2, 2009Date of Patent: December 2, 2014Assignees: BASF Plant Science GmbH, Bioriginal Food & Science Corp.Inventors: Jörg Bauer, Xiao Qiu, Patricia Vrinten
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Patent number: 8889950Abstract: The present invention relates to methods that may be used to improve or modify nutrient sensing, absorption, metabolism, root growth, stomatal conductance, N use efficiency, C and N metabolism, plant biomass production and seed yield. More specifically, this invention is related to the glutamate receptors (GLRs) and their role(s) in nutrient sensing, metabolism, regulation of growth, development, and yield.Type: GrantFiled: July 28, 2007Date of Patent: November 18, 2014Assignee: The George Washington UniversityInventors: Sivasubramanian Balasubramanian, Frank J. Turano
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Patent number: 8889949Abstract: The present invention relates to a method for increasing resistance of monocot plants against abiotic stress which comprises a step of transforming monocot plants with a recombinant plasmid containing a fused gene (TPSP) of trehalose-6-phosphate synthetase (TPS) gene and trehalose-6-phosphate phosphatase (TPP) gene to express the TPSP gene while maintaining normal growth and development characteristics. The present invention can increase the resistance of monocot plants against various stresses so that it can greatly contribute to the improvement of production and quality of valuable agricultural crops. The present invention also relates to a transgenic monocot plant, plant cell, or protoplast transformed with a nucleic acid encoding an enzyme for trehalose biosynthesis, under control of an inducible promoter, that increases tolerance to low temperature, salt, and water stress.Type: GrantFiled: January 3, 2007Date of Patent: November 18, 2014Assignees: Cornell Research Foundation, Inc., Myongji University Industry and Academia Cooperation FoundationInventors: Ray J. Wu, Ajay K. Garg, Ju-Kon Kim, Baek-Hie Nahm, Yang-Do Choi, In-Cheol Jang, Won-Bin Choi, Yeon-Seak Kim, Chung-Ho Kim, Sang-Ik Song
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Patent number: 8865969Abstract: According to the present invention, a technique of increasing the frequency of genetic recombination in genomic DNA of a plant is established. Such technique comprises: introducing a restriction enzyme gene that can be expressed in a target plant cell into the plant cell and causing the restriction enzyme gene to be transiently expressed so as to induce genetic recombination of genomic DNA; or introducing a promoter and a restriction enzyme gene using the Agrobacterium method so as to induce genetic recombination of genomic DNA.Type: GrantFiled: January 18, 2011Date of Patent: October 21, 2014Assignees: Toyota Jidosha Kabushiki Kaisha, RikenInventors: Satoshi Kondo, Chikara Ohto, Kunihiro Ohta, Shuichi Ohsato, Norihiro Mitsukawa, Nobuhiko Muramoto, Hiroki Sugimoto
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Patent number: 8865451Abstract: The present disclosure relates to transgenic algae having increased growth characteristics, and methods of increasing growth characteristics of algae. In particular, the disclosure relates to transgenic algae comprising a glutamine phenylpyruvate transaminase transgene and to transgenic algae comprising a glutamine phenylpyruvate transaminase transgene and a glutamine synthetase.Type: GrantFiled: February 28, 2011Date of Patent: October 21, 2014Assignees: Los Alamos National Security, LLC, University of Maine System Board of TrusteesInventors: Pat J. Unkefer, Penelope S. Anderson, Thomas J. Knight
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Patent number: 8852885Abstract: Methods and compositions for the production of oil, fuels, oleochemicals, and other compounds in recombinant microorganisms are provided, including oil-bearing microorganisms and methods of low cost cultivation of such microorganisms. Microalgal cells containing exogenous genes encoding, for example, a lipase, a sucrose transporter, a sucrose invertase, a fructokinase, a polysaccharide-degrading enzyme, a keto acyl-ACP synthase enzyme, a fatty acyl-ACP thioesterase, a fatty acyl-CoA/aldehyde reductase, a fatty acyl-CoA reductase, a fatty aldehyde reductase, a fatty acid hydroxylase, a desaturase enzyme, a fatty aldehyde decarbonylase, and/or an acyl carrier protein are useful in manufacturing transportation fuels such as renewable diesel, biodiesel, and renewable jet fuel, as well as oleochemicals such as functional fluids, surfactants, soaps and lubricants.Type: GrantFiled: July 12, 2012Date of Patent: October 7, 2014Assignee: Solazyme, Inc.Inventors: Scott Franklin, Aravind Somanchi, Janice Wee, George Rudenko, Jeffrey L. Moseley, Walt Rakitsky, Xinhua Zhao, Riyaz Bhat
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Patent number: 8847014Abstract: Nucleotide sequences mediating male fertility in plants are described, with DNA molecule and amino acid sequences set forth. Promoter sequences and their essential regions are also identified. The nucleotide sequences are useful in mediating male fertility in plants.Type: GrantFiled: March 9, 2009Date of Patent: September 30, 2014Assignee: Pioneer Hi-Bred International, Inc.Inventors: Marc Albertsen, Tim Fox, Gary Huffman, Mary Trimnell
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Patent number: 8847010Abstract: The present invention relates to a genetically modified plant having an increased amount of oil in its green biomass as compared to the oil in the green biomass of its non-genetically modified counterpart. The plants may be used for producing bio-fuels such as biodiesel fuel.Type: GrantFiled: June 12, 2008Date of Patent: September 30, 2014Assignees: Biotechnology Foundation, Inc., Thomas Jefferson UniversityInventors: Hilary Koprowski, Vyacheslav Andrianov, Mykola Borsyuk
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Patent number: 8847012Abstract: This invention is intended to be used to search for a transcription factor having novel functions of increasing the weight of an individual plant, increasing the weight of a given tissue per individual plant, or improving the productivity of a given substance per individual plant and to improve such properties in the plant. The weight of an individual plant is increased, the weight of a given tissue per individual plant is increased, the productivity of a given substance per individual plant is improved, or the content of a given substance per given tissue of a plant is increased via expression of a transcription factor that has been modified to suppress transcription accelerating activity.Type: GrantFiled: December 5, 2008Date of Patent: September 30, 2014Assignee: Toyota Jidosha Kabushiki KaishaInventors: Hiroshi Chatani, Chikara Ohto, Yukio Okamura, Norihiro Mitsukawa, Nobuhiko Muramoto, Tomotsugu Koyama, Kyoko Matsui, Masaru Takagi
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Patent number: 8847011Abstract: This invention is intended to be used to search for a transcription factor having novel functions of increasing the weight of an individual plant, increasing the weight of a given tissue per individual plant, or improving the productivity of a given substance per individual plant and to improve such properties in the plant. The weight of an individual plant is increased, the weight of a given tissue per individual plant is increased, the productivity of a given substance per individual plant is improved, or the content of a given substance per given tissue of a plant is increased via expression of a transcription factor that has been modified to suppress transcription accelerating activity.Type: GrantFiled: December 5, 2008Date of Patent: September 30, 2014Assignee: Toyota Jidosha Kabushiki KaishaInventors: Hiroshi Chatani, Chikara Ohto, Yukio Okamura, Norihiro Mitsukawa, Nobuhiko Muramoto, Masaru Takagi, Nobutaka Mitsuda, Tomotsugu Koyama, Kyoko Matsui
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Patent number: 8828690Abstract: Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding multizymes (i.e., single polypeptides having at least two independent and separable enzymatic activities) along with a method of making long-chain polyunsaturated fatty acids (PUFAs) using these multizymes in plants and oleaginous yeast are disclosed.Type: GrantFiled: April 3, 2008Date of Patent: September 9, 2014Assignee: E I du Pont de Nemours and CompanyInventors: Howard G. Damude, Anthony J. Kinney, Kevin G. Ripp, Quinn Qun Zhu
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Patent number: 8802924Abstract: An isolated protein which is at least partially encoded by a polynucleotide sequence encoding a novel elongase is provided together with a composition which includes the isolated protein. A transgenic plant or a transgenic seed transformed by a polynucleotide encoding a protein which is at least partially encoded by a novel elongase is also provided. The invention also includes a process for making a very long-chain polyunsaturated fatty acid in a transformed cell or plant expressing the isolated protein which is at least partially encoded by a polynucleotide sequence encoding a novel elongase.Type: GrantFiled: November 26, 2009Date of Patent: August 12, 2014Assignee: Ben Gurion University of the Negev Research and Development AuthorityInventors: Zvi Hacohen, Inna Khozin Goldberg, Rivka Ofir, Iskandarov Umidjon
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Patent number: 8802921Abstract: A method for producing a transgenic plant includes providing a nucleic acid molecule comprising at least two regions of nucleic acid sequence that lack sequence homology with genomic DNA of the plant cell, and at least two zinc finger nuclease recognition sites, wherein the at least two regions of nucleic acid sequence that lack sequence homology with genomic DNA of the plant cell flank the at least two zinc finger nuclease recognition sites. A plant cell or tissue having the nucleic acid molecule stably integrated into the genome of the plant cell is transformed. A plant is regenerated from the plant cell. Transgenic plants are produced by the method. Seeds are produced by the transgenic plants.Type: GrantFiled: January 21, 2011Date of Patent: August 12, 2014Assignee: Dow AgroSciences, LLC.Inventors: William M. Ainley, Ryan C. Blue, Michael G. Murray, David Corbin, Rebecca R. Miles, Steven R. Webb
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Patent number: 8802928Abstract: The present invention relates generally to the field of molecular biology and concerns a method for enhancing various economically important yield-related traits in plants. More specifically, the present invention concerns a method for enhancing yield-related traits in plants by modulating expression in a plant of a nucleic acid encoding a Yield Enhancing Protein (YEP). The YEP is selected from a Nucleosome Assembly Protein 1-like polypeptide (NAP1-like), a Like Sm polypeptide (Lsm protein), a truncated Cyclin H (CycHTr) polypeptide, a Remorin polypeptide, and a DREB protein. The present invention also concerns plants having modulated expression of a nucleic acid encoding such a YEP, which plants have enhanced yield-related traits relative to control plants. The invention also provides hitherto unknown YEP-encoding nucleic acids, and constructs comprising the same, useful in performing the methods of the invention.Type: GrantFiled: January 31, 2008Date of Patent: August 12, 2014Assignee: BASF Plant Science GmbHInventors: Ana Isabel Sanz Molinero, Valerie Frankard, Yves Hatzfeld, Christophe Reuzeau
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Patent number: 8785727Abstract: The present invention relates to a polynucleotide from Emiliana huxleyi which codes for a desaturase and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotide according to the invention, and to the polypeptides encoded by the polynucleotide. The invention furthermore relates to antibodies against the polypeptide according to the invention. Finally, the invention also relates to production methods for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to their use as drugs, cosmetics, foodstuffs, feedstuffs, preferably fish food, or food supplements.Type: GrantFiled: April 29, 2009Date of Patent: July 22, 2014Assignee: Rothamsted Research Ltd.Inventors: Joerg Bauer, Johnathan A. Napier, Olga Sayanova
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Patent number: 8759610Abstract: The cloning and broad characterization of a lyso-phosphatidic acid acyltransferase (LPAT2) from Tropaeolum majus is described. The TmLPAT2 enables the production of plants, seeds and cells with enhanced oil and/or fatty acid content. In particular, recombinant TMLPAT2 increases levels of very long chain fatty acids (VLCFA), especially erucic acid, in plants, seeds and cells.Type: GrantFiled: February 3, 2010Date of Patent: June 24, 2014Assignee: National Research Council of CanadaInventors: David C. Taylor, Tammy Francis