Abstract: A catheter includes a distal distension balloon and circumferentially arranged motility measurement balloons proximal of the distension balloon. A manifold includes balloon ports each configured to fluidly couple to a motility measurement balloon, pressure transducer ports, and a priming port. A port selector is coupled to the manifold and movable between different positions. Each port selector position causes the manifold to establish different fluidic couplings between the respective motility balloon, pressure transducer, and priming ports. A pressure sensing device includes pressure transducers each fluidly coupled to one of the pressure transducer ports. The pressure sensing device is configured to coordinate calibration of the pressure transducers at atmospheric pressure with the port selector in a first position and motility balloon pressure measurements with the port selector in a third position.

Abstract: Methods and systems for seamless adjustment of treatment are disclosed. A determination is made as to whether to intervene with a patient's treatment. Implanted device memory data is acquired over a pre-specified time period. Risk status is determined from the device memory data. Another external device memory data is acquired over a pre-specified time period. A determination is made as to whether to adjust treatment of the patient in response to the risk status, the data acquired from the implanted device memory and the external device memory data.

Abstract: Provided herein are systems, devices, and methods for sample collection. A sample collection device may comprise a vessel, a lid, and pre-loaded liquid solutions. The sample collection device may collect a liquid sample, such as a biological sample. The liquid solutions may comprise reagents for preserving and/or stabilizing biological samples, such as saliva, collected in the vessel. A chamber comprising the liquid solutions may be located in the vessel and/or the lid. In some instances, the liquid solution may be released from the chamber upon closure of the vessel with the lid. In some instances, the liquid solution may be released from the chamber upon actuation of an implement, such as a plunger. In some instances, the liquid solution may be released upon compression of an absorbent member. The sample collecting device may be delivered to a remote location for further processing and/or analysis.

Abstract: An eye sensor, system and method for measuring fixational eye movements of an individual's eyeball (e.g., ocular microtremors and microsaccades) to provide a variable voltage biosignal for measuring the individual's brain stem activity. The eye sensor comprises a sensor mounted on the individual's closed or opened eyelid so as to be deflected by the fixational eye movements of the eyeball. A shielded flexible ribbon assembly supplies the biosignal generated by the sensor to an amplifier located on the individual's skin where the biosignal is amplified. The amplifier is interconnected with a signal processor and a display by which graphical and numerical representations of the biosignal are made accessible to an anesthesiologist, intensivist or clinician. A method for analyzing the biosignal to determine the brainstem activity of a patient.

Abstract: An apparatus for and a method for estimating blood pressure are provided. The apparatus for estimating blood pressure includes: a sensor configured to measure a pulse wave signal from an object; and a processor configured to obtain a mean arterial pressure (MAP) based on the pulse wave signal, configured to classify a phase of the obtained MAP according to at least one classification criterion, and to obtain a systolic blood pressure (SBP) by using an estimation model corresponding to the classified phase of the MAP among estimation models corresponding to respective phases of the MAP.

Abstract: Introduced here are electronic stethoscope systems designed to simultaneously monitor sounds originating from within a body under examination and the ambient environment. An electronic stethoscope system can include one or more input units that are connected to a hub unit. Each input unit may have at least one auscultation microphone and at least one ambient microphone. To improve the quality of sound recorded by an input unit, a processor can apply a noise cancellation algorithm that considers as input the audio data produced by the auscultation microphone(s) and the audio data produced by the ambient microphone(s). The audio data may be digitized directly in the input unit, and then transmitted to the hub unit for synchronization. For example, by examining the audio data produced by the ambient microphone(s), the processor may discover which digital artifacts, if any, should be filtered from the audio data produced by the auscultation microphone(s).

Abstract: A flexible sensor configured for use in a bladder is flexible and moveable from a first position in which it is configured to not be discharged from the bladder to a second position in which it is configured to be inserted into the bladder. A sensor insertion tool includes an over sheath, a push rod configured to be inserted into a first lumen of the over sheath. The flexible sensor is positioned in the first lumen of the over sheath, the push rod is then inserted partially into the over sheath behind the flexible sensor. The sensor insertion tool is then positioned at a location, such as the opening to the bladder, in which the sensor is to be deployed.

Abstract: The device as disclosed herein is to measure breath humidity, the device comprises an inlet fluidly connected at a first end of a tubular body, said tubular body defining an inner tube volume. The device further comprises a condenser plate, fluidly connected to the second end of the tubular body to receive exhaled breath. A partition wall intermediate the first and second ends divides the inner tube volume into first and second chambers, the second chamber providing fluid access to the condenser plate. The wall has a one-way valve therethrough allowing breath from the first to the second chamber. The device further comprises one or more apertures in the tubular body wall of the first chamber, the or each aperture fluidly linking a sensor to the first chamber, and a relative humidity sensor fluidly linked to the second chamber.

Abstract: System and method for measuring hypertension conditions of a subject is disclosed. The disclosed system and method includes thermal sensors for capturing thermal images and/or videos of a body part; and a processing engine to detect a predefined region of the body part in each frame of the captured images and/or videos. The processing engine segments one or more portions from the detected predefined region in each frame of the captured images and/or videos to identify a region of interest comprising arteries in the one or more segmented portions. Based on the identified region of interest, the engine extracts pixel values from each frame of the captured images and/or videos to determine parameters associated with a blood flow velocity and a blood pressure of the subject. Further a type of hypertension and a risk score for the hypertension condition based on the determined parameters using computational models are measured.

Abstract: The objective of the present invention is to provide a liquid sample collector capable of collecting a trace amount of a specimen such as a tear safely and in an adequate amount. This trace amount liquid sample collector is characterized in that: the liquid sample collector is provided with a main body and a first absorbent body; the main body has at least one open end portion; the main body includes a hydrophobic material having elasticity; the first absorbent body is disposed at least partially inside the main body; the first absorbent body includes a water-absorbent material; and the first absorbent body is disposed in such a way as to be capable of coming into contact with the outside by way of the at least one open end portion of the main body.

Abstract: A system is configured for receiving force data including at least one value indicating the amount of the force applied to the portion of the user and at least one value indicating a direction of the force applied to the portion of the user; obtaining mapping data specifying at least one relation between values of force applied to the portion of the user and changes in a functional responsiveness, functional and/or structural integrity, or both the functional responsiveness and the functional and/or structural integrity of the brain at one or more locations in the brain; estimating, based on the mapping data and the force data, an amount of force loading at one or more particular locations in the brain; and generating, based on the estimating, output data representing an amount of the damage to the brain at the one or more particular locations in the brain.

Abstract: A system and method for automatic determination of type of pneumatic cuff is disclosed. A system can include a pneumatic cuff with an integrated valve, and a console connectable to the pneumatic cuff. The console can be a pneumatic control system that can include a processor and memory including instructions, which when executed by the processor causes the processor to: inflate the pneumatic cuff through the integrated valve past a threshold pressure such that the integrated valve opens, receive sensor data indicative of a pressure curve during inflation of the pneumatic cuff, compare the pressure curve to stored pressure curves, determine a recommendation, based on the comparison, including information verifying the type of pneumatic cuff attached, and output the recommendation to a user.

Abstract: A biopsy valve includes a body having a first groove adapted to fit over a lip of an endoscope working channel and a second groove and a first membrane. A primary cap is mechanically coupled to the body by a primary strap extending between the primary cap and the body. The primary cap includes a primary cap lip to couple into the second groove of the body, a second membrane and a primary cap groove. A guard cap is mechanically coupled to the body by a guard cap strap extending between the guard cap and the body. The guard cap includes a guard cap lip which couples into the primary cap groove of the primary cap, and a third membrane. A triple membrane biopsy valve and a method of using a biopsy valve with an endoscope working channel are also described.

Abstract: A flexible sensor configured for use in a bladder is flexible and moveable from a first position in which it is configured to not be discharged from the bladder to a second position in which it is configured to be inserted into the bladder. A sensor insertion tool includes an over sheath, a push rod configured to be inserted into a first lumen of the over sheath. The flexible sensor is positioned in the first lumen of the over sheath, the push rod is then inserted partially into the over sheath behind the flexible sensor. The sensor insertion tool is then positioned at a location, such as the opening to the bladder, in which the sensor is to be deployed.

Abstract: A method is provided which includes providing a sensor operable to measure movement over time on a user. The sensor includes an alert unit. The sensor is configured with a threshold to activate the alert unit when the measured movement over time is below the threshold. The measurements of movement over time are obtained, and it is determined whether the measured movement over time is below the threshold. When the measured movement is below the threshold, the alert unit at the sensor is activated to alert the user.

Abstract: A wearable sensor decal may include a flexible wrapper layer, an intermediate layer, and a porous film layer. A first plurality of electrodes may be deposited on the wrapper layer. A heating element may be conductivity coupled to the first plurality of electrodes. A second plurality of electrodes may be deposited on the intermediate layer. A biosensor may be conductively coupled to the second plurality of electrodes. The flexible film may be hydrophilic to allow biofluids pass to the biosensor and the wrapper layer may be hydrophobic to provide waterproofing to the biosensor and heating element. The heating element may be powered to reduce thermal variance in biosensor measurements.

Abstract: A non-invasive continuous blood sugar level monitoring apparatus integrated with real-time health support system. The blood sugar levels and other vital physiological information of the user can also be tracked wirelessly through the apparatus. The apparatus has an integrated real-time alert and reminder feature for notifying the user during medication and unusual physiological conditions. An automated diet and lifestyle recommendation solution is integrated into the device to help the user maintain healthy blood sugar and blood pressure levels. The low-powered telemetry device is used for communicating the stored physiological information of the user and the computed results between the network of devices.

Abstract: Provided are a biological sound measurement device capable of detecting contact with a body surface of a living body with a simple configuration, a control method for the biological sound measurement device, and a non-transitory recording medium storing a control program for the biological sound measurement device. The biological sound measurement device (1) includes: a measuring unit (3) that detects a biological sound of a living body in a state of contact with a body surface S of the living body; and a contact state determination unit (41) that determines whether or not a contact state is active in which the measuring unit (3) is in contact with the body surface S, based on a change in a sound pressure level of sounds detected by the measuring unit (3).

Abstract: A system includes a computer including a processor and a memory storing instructions executable by the processor to detect a position of a head of an occupant within a passenger compartment of a vehicle. The instructions include instructions to conduct a hearing test based on the position of the head of the occupant. The instructions include instructions to output sound at least at one of a specified frequency or amplitude, the specified frequency or amplitude selected based on results of the hearing test.

Abstract: A blood pressure measurement device that measures blood pressure, and relates to a cuff unit.