Abstract: Novel benzylphosphonate compounds of the general formula I: ##STR1## are disclosed as useful in treating bone wasting diseases including postmenopausal osteoporosis in increasing in mammals bone formation and bone mass.
Type:
Grant
Filed:
July 18, 1991
Date of Patent:
April 5, 1994
Assignee:
Ortho Pharmaceutical Corporation
Inventors:
Charles Schwender, Keith Demarest, David Wustrow
Abstract: Herbicidal nitrogen-containing N-aryl-heterocycles of the formula ##STR1## in which Het represents a heterocycle of the formula ##STR2## X.sup.1 represents oxygen, a --CH.sub.2 -- group or an ##STR3## X.sup.2 represents nitrogen or a CH group, Z.sup.1 represents oxygen or sulphur andn represents the number 0 or 1.
Type:
Grant
Filed:
September 28, 1990
Date of Patent:
April 28, 1992
Assignee:
Bayer Aktiengesellschaft
Inventors:
Franz Kunisch, Klaus Lurssen, Hans-Joachim Santel, Robert R. Schmidt