Abstract: The present invention is a device which allows for receiving, distributing and storing a sample into numerous aliquots of small volume without air entrapment and with retention of aliquots when the device is manipulated. The device allows for the treatment of any or all of the aliquots with the same or different reagents and/or other chemical additives. The device comprises a housing for containing a body for guiding a sample into a plurality of wells without the need for pipetting aids, without multiple manipulations, without the retention of air and for retaining sample in the wells.

Abstract: An apparatus is disclosed that separates and removes to an external source, spent cell culture media from a cell culture media and cell culture mixture. The apparatus generally comprises a culture vessel, a filter member, wherein the filter member is positioned in the culture vessel to form an outside region and an inside region. Further provided is a tube member. The tube member being positioned in the inside region and having an opening therein to thereby remove the spent cell culture media brought into the inside region. Further disclosed is a structure for rotating the filter member around the tube member and a structure for sealing the outside region from the inside region when the filter member is rotating around the tube member.

Abstract: A dry strip element for use in an electrochemical assay for determining theophylline in a sample, the test element carrying a working electrode and a reference electrode and separately carrying at the working electrode an alkaline phosphatase and an electroinactive phosphate ester which is a substrate for the alkaline phosphatase and from which an electroactive compound can be released by catalytic activity of the alkaline phosphatase.