Abstract: An antibody or antigen-binding fragment thereof is disclosed. The antibody or antigen-binding fragment thereof binds to HER2 expressed on a cancer cell or a fragment of the HER2. A HER2-targeting agent containing any of the antibody or antigen-binding fragment thereof, and a pharmaceutical composition containing the HER2-targeting agent are disclosed.
Type:
Grant
Filed:
August 4, 2023
Date of Patent:
May 14, 2024
Assignees:
ONO PHARMACEUTICAL CO., LTD., TOHOKU UNIVERSITY
Inventors:
Yukinari Kato, Mika Kaneko, Daisuke Nakayama, Masayuki Kurogi
Abstract: An antibody targeting Galectin-9 is provided as are methods of using the same treatment of chronic immune conditions such as infections, inflammatory diseases and cancer, in particular malignant mesothelioma.