Abstract: A high intensity preparation, physical exercise and recovery system configured to prepare muscles for workout through vibration, accept muscular input of high intensity, recover muscles through vibration. Embodiments provide an exercise system that enables a user to obtain a high intensity workout in a small amount of time, for example 15 minutes, and yet increase the user's metabolic rate for hours. Embodiments of the invention may further perform an initial and/or ongoing analysis in terms of body composition analysis and/or extremity composition analysis/score in order to target particular muscles, fat and/or skeletal areas. In one or more embodiments the system may provide outputs including suggested alterations in physical activity and/or food to consume in order to achieve targeted goals for example as compared to the user's trends of change over time, or in comparison to other user's trends down to the granularity of extremities and not just overall body metrics.

Abstract: Described is an infant monitoring and alerting system capable of determining an absence of movement by an infant. When an absence of movement is detected the monitor attempts to stimulate movement using stimuli that may include a vibration, an audible alert, or a visual alert. If no movement is detected in response to the stimuli, the monitor may provide another instance of stimuli which may include stimuli at an elevated intensity or additional and/or different stimuli. The additional instance of stimuli may further attempt to stimulate movement by the infant and may also function as an alert to the caregiver that their attention may be required.

Abstract: An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve. For example, such a device may be used to measure fractional flow reserve (FFR) across a stenotic lesion in order to assess the severity of the lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. Some distance back from the sensor and distal sleeve, the device separates from the guidewire to permit independent control of the sensor delivery device and the guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example.

Abstract: A medical device such as an oximeter includes a marking feature. In an implementation, a marking mechanism of the device marks tissue based on a location of where a measurement was taken by the device. In an implementation, the marking mechanism of the device marks tissue based on an oxygen saturation measurement obtained by the device.

Abstract: Systems and methods for monitoring physiological parameters such as intracranial pressure (“ICP”), intracranial temperature, and subject head position are provided. In some embodiments, an implantable apparatus for measuring ICP can be implanted into a subject skull. The apparatus can comprise an implant body having a hermetically sealed chamber housing a gas at a reference pressure, and a pressure conduction catheter having a proximal end and a distal end, wherein the distal end is configured to extend into the brain through a burr hole in the skull and includes a plurality of ports. A barrier can cover the ports of the distal end of the pressure conduction catheter, wherein the barrier and pressure conduction catheter are filled with a number of gas molecules so that the barrier is not in tension in a predefined range of ICPs. The ports may also be configured such that a barrier is not necessary.

Abstract: The device performs reference point indentation without a reference probe. The indentation distance is measured relative to the instrument which remains substantially stationary during the impact process, which occurs on the order of one millisecond. In one embodiment, an impact motion with a peak force of order 28N creates an indentation in bone with a depth of approximately 150 ?m during which the instrument case moves less than 1 ?m. Thus the error in measuring indentation depth due to the motion of the case is less than 1%, making a reference probe unnecessary. Further, this “error” is consistent and can be corrected. In one embodiment, the device measures the fracture resistance of hard tissues by actually creating microscopic fractures in the hard tissues in a measured way. It creates these microscopic fractures by impacting the sample with a sharpened probe. The indentation distance in the sample is correlated with fracture resistance.

Abstract: The present disclosure provides a system and method for determination and indication of the time remaining before a patient's physical characteristics are displayed on a monitor. The indication may be a numeric count-down, a progress bar, a clock face, an audible signal, or any other time and/or progress indication. The approximate wait-time may be determined, for example, by adding the known, generally fixed durations of characteristic determination processes to the calculated, variable durations of characteristic determination processes. Exemplary processes which may have generally fixed durations include monitor boot-up, sensor validation, and sensor calibration. Exemplary processes which may have variable durations include sensor location determination and pulsation detection. The sum of the pre-determined and calculated durations may be an approximate wait-time, which is indicated to a caregiver via visual or audible display.

Abstract: The invention provides a save and non-invasive alternative to the traditional modified Evans blue dye test for dysphagia in intubated patients. The method employs direct application of dye to the tongue, in combination with a tracheal tube that provides suction in the subglottal region above the cuff. By keeping the cuff inflated, the aspiration of food and liquid, as used in the traditional test, is avoided entirely.

Abstract: Guide wire devices fabricated from a linear pseudo-elastic Ni—Ti alloy and methods for their manufacture. The Ni—Ti alloy that includes nickel, titanium, and about 3 atomic % (at %) to about 30 at % niobium (Nb). Cold working the Ni—Ti alloy stabilizes the alloy's martensitic phase and yields a linear pseudo-elastic microstructure where reversion to the austenite phase is retarded or altogether blocked. The martensitic phase of cold worked, linear pseudo-elastic Ni—Ti—Nb alloy has an elastic modulus that is considerably higher than the comparable cold worked, linear pseudoelastic binary Ni—Ti alloy. This yields a guide wire device that has better torque response and steerability as compared to cold worked, linear pseudoelastic binary Ni—Ti alloy or superelastic binary Ni—Ti alloy.

Abstract: Various embodiments concern identifying a biomarker in the presence of electrical stimulation. Various embodiments concern delivering electrical stimulation to a patient and sensing one or more signals while the electrical stimulation is being delivered, the one or more signals including data indicative of physiological activity. Various embodiments further include determining an intensity of the electrical stimulation and determining whether the data indicates the presence of a biomarker based on a variable threshold, the variable threshold being variable based on the intensity of the electrical stimulation. Various embodiments concern determining a relationship between stimulation intensity and a biomarker parameter to determine the variability of the variable threshold.

Abstract: An apparatus for neural block determination is provided including processing circuitry configured to receive muscle movement measurements, analyze the muscle movement measurements in a frequency domain, and determine an effectiveness of an anesthetic based on the analysis of the muscle movement measurements in the frequency domain.

Abstract: The invention relates to a test element as a single-use article for examining a body fluid, comprising a lancing member that can be inserted into a body part, a collecting area configured thereon for body fluid obtained by the lancing and at least one light guide for an optical measurement in the collecting area. The collecting area is formed by a collection recess of the lancing member which extends in the lancing direction and the light guide is integrated into the lancing member such that it is secure against displacement and the distal end thereof is arranged in a proximal measurement zone of the collection recess.

Abstract: A gesture recognition biofeedback device is provided for improving fine motor function in persons with brain injury. The system detects a physical characteristic of the patient and provides feedback based on the detected characteristic. For instance, the system may detect surface muscle pressures of the forearm to provide real-time visual biofeedback to the patient based on a comparison of the detected muscle pressure and predefined values indicative of appropriate motor function.

Abstract: The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a treatment delivery system for treating a subject in response to changes in the severity of a subject's symptoms. The present invention further provides for a system and method, which can accurately quantify symptoms of movement disorders, utilizing continuously obtained kinetic information to be analyzed, accurately distinguishing between symptoms of movement disorders and activities of daily living, relating quantified symptoms to a standard clinical rating scale, and correlating a subject's symptoms with certain physiological and environmental factors. The present invention still further provides for home monitoring of symptoms in subjects with these movement disorders in order to capture the complex fluctuation patterns of the disease over the course of days, weeks, months, or years.

Abstract: A biosignal measuring method and apparatus are provided. The biosignal measuring method includes verifying whether a measured biosignal is in a range, and controlling an operation of the biosignal measuring apparatus when the measured biosignal deviates from the range based on a result of the verifying.

Abstract: Intravascular devices, systems, and methods are disclosed. In some embodiments, a method of assembling an intravascular device is provided that include positioning a first tubular member around a plurality of conductors and a core member such that the plurality of conductors and the core member are at least partially positioned within a lumen of the first tubular member, the first tubular member including an opening extending along a length of the first tubular member in communication with the lumen; positioning a first conductive member around the first tubular member; advancing a first of the plurality of conductors through the opening of the first tubular member, longitudinally between the first tubular member and the first conductive member, and through to a position adjacent to the first conductive member; and electrically coupling the first of the plurality of conductors to the first conductive member.

Abstract: The present invention relates to a medical device for intradermal or subcutaneous treatment of a patient, comprising: a piercing element to penetrate a skin portion of the patient; an illumination arrangement to illuminate the piercing element and/or to illuminate the skin portion prior and/or during a treatment process, wherein the illumination arrangement is further adapted to visually indicate a predefined treatment sequence of the treatment process.

Abstract: The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides remote access to the clinician or physician.

Abstract: A medical evaluation system includes an I/O module, a processing module, and an analysis module. The I/O module receives sensory data obtained by a motion sensor disposed in a mobile device carried by a patient at least when the patient is in a non-clinical environment. The processing module extracts medically relevant data from the sensory data received from the sensor in the mobile device. The relevant data includes one or more features of interest in the sensory data. The analysis module derives one or more surrogate biomarkers from the relevant data. The surrogate biomarkers represent at least one of a state or a progression of a medical condition of the patient. The mobile device may be a mobile phone carried by the patient and the sensor may include at least one of an accelerometer or a gyroscope that generates the sensory data to represent movements of the patient.

Abstract: A needle for fine-needle aspiration includes an elongated body extending from a proximal end to a distal end along a central longitudinal axis and having a channel extending therethrough, a distal portion of the body being movable between a first configuration in which the distal portion extends parallel to the central longitudinal axis and the channel is unobstructed and a second configuration in which the distal portion is axially offset relative to the central longitudinal axis to seal at least a portion of the channel and an actuation mechanism controlling movement of the distal portion between the first and second configurations.