Abstract: A syringe, on which a needle member is mounted, includes a barrel, a plunger and a stopper. The barrel has a chamber, a stop portion adjacent to the needle member, a lock portion on a wall of the chamber and a needle mount. The plunger has a lock device and an operation portion for operation. A stopper has a stopper body to be squeezed into the chamber of the barrel for movement, a lock flange on the stopper body to be elastically deformed and to be locked with the lock portion of the barrel. The lock device is provided to the stopper body to be connected to the lock device of the plunger that connects the stopper to the plunger to move together. While the plunger is drawn, the lock device of the plunger or the stopper is broken and the stopper is restricted in the barrel.

Abstract: The present invention relates to a medical device and a method of delivering a drug to a target circulation or tissue. The medical device has an expandable portion which is fabricated from a porous elastomeric material with a plurality of voids therein. The voids are loaded with drugs in various formulations. Upon inflation of the expandable portion, the overall diameter increases, the wall thickness decreases and, consequently, the voids are stretched to cause the drug to be expelled from the voids and into the bodily lumen or tissue adjacent to the medical device. The voids include any open volume within the expandable portion capable of containing the drug.