Abstract: A movable body monitoring apparatus is configured to be mounted on a movable body and to receive movement data related to movements of other movable bodies. The apparatus includes an acquiring unit, a generator, and a monitoring unit. The acquiring unit is configured to acquire the movement data on the other movable bodies. The generator is configured to generate, for low-speed movable bodies that are determined based on an actual speed or a type of the other movable bodies, a monitoring curve that curves along positions of a plurality of low-speed movable bodies. The monitoring unit is configured to monitor movements of the plurality of low-speed movable bodies based on a movement of the generated monitoring curve.

Abstract: A method for supporting energy-efficient deceleration of a vehicle includes determining a reference deceleration depending on a current speed or a speed profile of the vehicle, determining a starting time point and a starting speed of a deceleration of the vehicle, and determining a real energy consumption and a real distance between the starting time point and a current time point and/or ending time point of the deceleration. The method also includes calculating a reference time and a reference distance for a deceleration with the determined reference deceleration between the determined starting speed and the current speed and/or the speed at the ending time point of the vehicle, calculating an energy consumption for a differential distance from the determined real distance and the calculated reference distance, and calculating a real total energy consumption as the sum of the determined real energy consumption of the deceleration and the calculated energy consumption for the differential distance.

Abstract: A method, a device, and a storage medium for providing a running road of an urban road are provided in the present disclosure. The method includes: obtaining a weighed road length of a specified urban road according to user track data of the specified urban road and road network data of the specified urban road; obtaining an actual passing period of the specified urban road according to the road network data of the specified urban road and road condition data of the specified urban road; obtaining a running speed of the specified urban road according to the weighed road length of the specified urban road and the actual passing period of the specified urban road; and providing the running speed of the specified urban on digital map products.

Abstract: An autonomous driving system installed on a vehicle includes: an information acquisition device configured to acquire driving environment information indicating driving environment for the vehicle; and an autonomous driving control device configured to control autonomous driving of the vehicle based on the driving environment information. The driving environment information includes: map information; and size information indicating a size of a routing object that moves integrally with the vehicle. The autonomous driving control device refers to the map information and the size information to determine a travel route through which the routing object can pass without protruding from a roadway as a target travel route to a destination.

Abstract: A method and system for controlling motor driven power steering are provided. The system includes a magnetic field generation detection module that detects generation of a magnetic field upon operating an electric part of a vehicle and a torque offset determination unit that determines whether a temporary torque offset has occurred in a torque to be applied to a motor based on a detection signal of the magnetic field generation detection module. A torque offset correction unit then corrects the torque offset to a normal torque range based on a torque offset correction logic in response to determining that the torque offset has occurred.

Abstract: An approach for analyzing and predicting a pattern of debris accumulation in area based on a deviation in mobility pattern. The approach includes receiving data from one or more sensors from an area and identifying objects based on the received data. The approach determines whether the received data is a first instance and stores the data. Based on the stored data, the approach analyzes, via machine learning, a mobility pattern associated with the retrieved data. Furthermore, the approach generates an actionable task list based on the analyzed data and instructs one or more computing devices based on the actionable task list.

Abstract: Systems and methods for operating an engine in a multi-engine rotorcraft are described herein. A first parameter indicative of torque of a first engine is obtained. A decrease of the first parameter is detected. In response to detecting the decrease of the first parameter, an autorotation of the rotorcraft is accommodated, A second parameter indicative of torque of a second engine of the rotorcraft is assessed while accommodating the autorotation. If the second parameter has not decreased, a shaft shear of the first engine is identified and accommodating of the autorotation is ended. If the second parameter has decreased, the accommodating is maintained.

Abstract: Provided are pharmaceutical means and methods for the prevention, treatment or amelioration of indolent or aggressive B cell non-Hodgkin lymphoma (B NHL) and B cell leukemia comprising the administration of a bispecific single chain antibody construct to a subject in the need thereof and the use of said bispecific single chain antibody construct for the preparation of a pharmaceutical composition for the prevention, treatment or amelioration of indolent or aggressive B cell non-Hodgkin lymphoma (B NHL) and B cell leukemia, whereby said construct is to be administered for at least 1 week in specified daily doses. Moreover, the invention relates to kits comprising a bispecific single chain antibody construct to be used in accordance with this invention.

Abstract: A method for operating a driver-assistance system of a vehicle includes switching from a distance controller of the driver-assistance system to an adaptive cruise control of the driver-assistance system as a function of a driver input by a driver of the vehicle expressed by an angular position of an accelerator pedal of the vehicle.

Abstract: The present technology relates to an imaging device, a signal processing device, and a vehicle control system enabling proper driving support when a vehicle enters a road from the outside of the road. An imaging device includes: an imaging unit that captures an image of a front of a vehicle; and an object detection unit that performs object detection processing on the basis of the image captured by the imaging unit, wherein the object detection unit changes an object detection method on the basis of a positional relationship between the vehicle and a road where the vehicle enters from an outside. The present technology can be applied to an imaging device installed in, for example, various vehicles that perform driving support.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: A vehicle control system including: a recognizer that is configured to recognize a surroundings status of a vehicle; and a driving controller that is configured to control an acceleration and steering of the vehicle on the basis of the surroundings status recognized by the recognizer, wherein, in a case in which a plurality of pedestrians are recognized in an advancement direction of the vehicle by the recognizer, the driving controller is configured to executes follow control for following the plurality of pedestrians and is configured to determines details of the follow control on the basis of a behavior of a nearest pedestrian who is closest to the vehicle among the plurality of pedestrians and a behavior of a second pedestrian who is a monitoring target other than the nearest pedestrian among the plurality of pedestrians.

Abstract: In one aspect, the invention provides a method of making a bioactive peptide-bearing antibody, or fragment thereof, comprising (a) engrafting the amino acid sequence of at least one bioactive peptide of interest into (i) at least one of CDR-H1, CDR-H2 or CDR-H3 of a heavy chain variable region comprising one or more chicken framework regions and/or (ii) at least one of CDR-L1, CDR-L2 or CDR-L3 of the light chain variable region comprising one or more chicken framework regions, and (b) determining whether the antibody has substantially the same biological activity as the bioactive peptide.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: The present disclosure relates generally to multi-specific Fab fusion proteins (MSFP) which comprise an antibody Fab fragment with both N-termini fused to a fusion moiety (fusion moiety A or B). MSFP containing the Fab fragment exhibit significantly reduced binding ability of the Fab fragment to the Fab target. Binding of the Fab to its target is restored when the MSFP is clustered on a cell surface by binding of the fusion moieties to their target. The reduced binding of the Fab to its target, especially when presented on a cell surface in its native state, absent fusion moiety binding provides advantages such as: reduced side effects and allows desirable pharmacological effects of selectivity and specificity in a controlled manner.

Abstract: The invention relates to new identified mutations in the epidermal growth factor receptor gene, leading to amino acidic changes which highly correlate with the resistance to a therapy regimen comprising cetuximab. The invention includes peptide sequences and primers to detect the mutations, as well as kits for predicting the response of a subject to a therapy regime comprising cetuximab. In particular, the invention is useful in the therapy regimen applicable to metastasic colorectal cancer.

Abstract: Provided are anti-CD47 antibodies and fragments thereof. The antibodies and fragments thereof specifically bind to the CD47 protein. Methods of using the antibodies or fragments thereof for treating and diagnosing diseases such as cancer and atherosclerosis are also provided.

Abstract: The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.

Abstract: The present application discloses anti-GPNMB antibodies and methods of using the same. The antibodies are selected to bind to an epitope located in a C-terminal fragment of the protein and are selected for specificity in immunohistochemical assays. The antibodies are useful in, for example, immunohistochemical methods of detecting GPNMB-positive cells in tumors.