Abstract: A method and apparatus for assessing neuromuscular pathology in an individual, by (a) applying a plurality of stimuli to a peripheral nerve; (b) recording from the peripheral nerve, or from a muscle innervated by the peripheral nerve, at least one response to each stimulus; (c) processing each response into at least one response characteristic; (d) compiling the response characteristics from all of the responses into a plurality of descriptive parameters of the response characteristics; and (e) analyzing the plurality of descriptive parameters according to a function specific to the neuromuscular pathology so as to yield an indicator of the pathology.

Abstract: The invention disclosed herein provides a system and method for diagnosing lower urinary system conditions by receiving urodynamic data and subjective symptomatic impressions concerning a patient. The system and method then assigns weighted point values to the urodynamic data, for example, urethal pressure profiles due to sphincter contraction conditions such as urgency (2) and stress incontinence (4), and the subjective symptomatic impressions, quantifies norms for lower urinary system function, as a whole or in part, and quantifies recognized pathologies of lower urinary system conditions as degrees of departure from the norms. The system and method then determines a lower urinary system condition diagnosis of the patient, as a function of the degrees of departure from the norms, by invoking a set of rules to compare the weighted point values assigned and the quantified norms.

Abstract: Disclosed is a device for measuring body fat of an animal. Embodiments include an input unit for entering individual information of the animal, a bioelectric impedance input unit for measuring the bioelectric impedance of the animal, and a morphological measurement value input unit for entering morphological measurement values for the girth and length of the body of the animal. An impedance-based calculation unit calculates a body fat rate based on the bioelectric impedance, and a morphological measurement value-based calculation unit calculates the body fat rate based on the morphological measurement values. A calculation switching unit checks to determine whether the resulting bioelectric impedance is proper, and automatically switches between the impedance-based calculation unit and the morphological measurement value-based calculation unit depending on the result of the determination.

Abstract: The present invention facilitates the detection of an occurrence of a physiological action imparting a displacement to a body part at a natural frequency signature by virtue of a bio-filter pad including a viscoelastic interior for intimate juxtapositioning against the body part, and having a mechanical resonance frequency midway in the range of the frequency signature associated with the physiological action.

Abstract: In a medical guide wire, a core line securement portion (11) is provided in which the core wire (2) is fixed to an inner side of the helical coil body (3) so as to form a top leading end portion (10) between the core line securement (11) and the head plug (4). A flat plane structure (13) is formed in which the core wire (2) of the top leading end portion (10) gradually changes through stepped portions (S) so that the core wire (2) progressively reduces its thickness stepwisely while successively increasing its breadth stepwisely as approaching a foremost distal end of the top leading end portion (10). This provides an improved flexibility, sensitivity, torsibility and torque transmissibility with the flat plane structure (13) so as to be accessible to the diseased area with a high detective and ablative ability.

Abstract: A device is provided which is capable of determining an amount of exercise involved in walking, as well as of obtaining quantitative information about visceral fat in the abdominal part of a subject and which can be used handily by being carried with the subject. The visceral fat determining device with a step-counting function is configured as follows. The visceral fat determining device has a step-counting means for counting the number of steps involved in exercise such as walking done by a subject and a main body shaped to be portable. When body data of the subject such as the waist size of the subject is inputted to the visceral fat determining device through a manipulation section, the visceral fat determining device is capable of performing a computation of the body data based on a predetermined computing formula for obtaining quantitative information about the abdominal visceral fat of the subject.

Abstract: A body fluid sampling device includes a firing mechanism that is configured to be automatically cocked and fired. In one form, the device includes an electric motor that is operable to cock the firing mechanism and fire an integrated lancet/sampling device to form an incision in skin. Subsequent to formation of the incision, the integrated lancet device is temporarily removed from the skin to promote bleeding from the incision. After a specified period of time, the integrated lancet device is then repositioned against the skin in order to collect a fluid sample.

Abstract: The disclosure describes a multi-tube pressure sensor to measure the pressure at two sites that may be used in a therapeutic incontinence control system. The system senses urinary sphincter pressure and urethral pressure and sends the information to a stimulator that is capable of stimulation therapy to control sphincter contractility, thus reducing unwanted urinary incontinence. Measuring sphincter pressure is accomplished through the use of a tube placed through the sphincter and urethral pressure is measured by a second tube placed within the urethra, both tubes may be attached to a single module implanted within the bladder. Pressure within the tube generates an electrical signal that is sent wirelessly to an implanted stimulator connected to a lead positioned near pelvic floor nerves. An external device may be used to wirelessly send information to the implanted stimulator and inhibit stimulation in order for the patient to empty the bladder.

Abstract: An implantable medical device includes a housing for the implantable device that is sized for implantation in a chest region of a patient and includes a housing electrode. A left ventricular lead port is connectable to a proximal end of a lead having first and second insulated conductors that extend from the proximal end of the lead to corresponding first and second electrodes near a distal end of the lead. An electrical impedance measurement circuit is electrically connected to the left ventricular lead port and the housing electrode. The circuit may inject current between the first lead electrode and the housing electrode, and measure a voltage potential, created by the current injection, between the second lead electrode and the housing electrode. The ratio of the measured voltage to injected current may be used for assessing pulmonary edema. The lead electrodes may be located in a left ventricular coronary vein.

Abstract: Apparatus and methods for rotation test stimulus and analysis methods overcome many of the limitations of traditional clinical tests of peripheral vestibular function. An embodiment includes a rotational stimuli applied to the rotational motion for testing that includes two separate components, a bias component and a probe component. The bias component for rotational motion is designed to temporarily turn off vestibular responses in one ear while the responsiveness in the opposite ear is simultaneously evaluated using the probe component of the stimulus. Responses from application of these stimuli are analyzed by isolating and separating the bias response from the probe response. The bias and probe component responses are parameterized by applying curve fits of mathematical functions to the isolated bias and probe component responses. These parameters characterize the patient's vestibular function.

Abstract: A sizing apparatus for determining the anterior-posterior size of a distal end of a femur. The apparatus includes a block having a face engageable with the distal end of the femur, and a body mounted on the block and slidable relative to the block in a medial-lateral direction. A stylus is mounted on the body.

Abstract: An interstitial fluid (ISF) extraction device includes a penetration member configured for penetrating a target site of a user's skin layer and, subsequently, residing in the user's skin layer and extracting an ISF sample therefrom and at least three concentrically-arranged pressure rings, each adapted for applying pressure to the user's skin layer in the vicinity of the target site while the penetration member is residing in the user's skin layer. In addition, the ISF extraction device is configured such that (i) the pressure rings apply pressure in an oscillating manner with asymmetric deployment and retraction cycles and (ii) only one of the at least three concentrically-arranged pressure rings is deployed at a time, thereby mitigating an ISF glucose lag of the ISF sample extracted by the penetration member.

Abstract: A sampling device for sampling body fluid includes a lancet for making an incision, a capillary tube for drawing-up body fluid from the incision, and a test strip affixed to an upper end of the capillary tube for receiving the fluid. An absorbent pad can be disposed between the test strip and capillary tube for spreading-out the fluid being transferred to the test strip. An on-site analyzer such as an optical analyzer and/or an electrochemical analyzer can be mounted in the device for analyzing the fluid. Alternatively, a test strip can be slid through a slot formed in the bottom end of the device so that by passing the device against the skin after an incision has been formed, the test strip will directly contact body fluid emanating from the incision.

Abstract: An automatic tissue sampling apparatus for use with a biopsy needle set having an inner needle and an outer cannula is provided. The apparatus includes a slidably disposed, spring-biased carrier for each of the inner needle and cannula A cocking mechanism is operable to sequentially move the first carrier to its cocked position and the second carrier to its cocked position. The cocking mechanism includes a manually operated cocking lever positioned outside the housing for single handed manipulation while holding the housing. A force transmission mechanism is operably coupled between the cocking lever and the carriers and configured so that the force required to manually depress the cocking lever to force the springs to the cocked positions does not increase as the springs are compressed.

Abstract: A procedure for diagnosing cochlear hydrops is based, in part, on an analysis of the patient's auditory brainstem response (ABR) to stimuli. The patient's ABR to a broadband click stimulus is recorded. A plurality of masked ABR's are also recorded, wherein the stimulus is masked by high-pass noise with a plurality of high-pass cut-off frequencies. The latency difference between the wave V component in the unmasked click alone response and the undermasked wave V component of a low cut-off frequency high-pass response is then calculated. If an undermasked component is not present, the normal wave V component is used. The measured latency difference is combined with another measure, such as the wave V amplitude ratio. A distribution of the combined measure is then plotted for the population and a threshold established for diagnosing cochlear hydrops. Alternatively, the joint distribution of the individual measures may be used in situations where the individual measures are known to be independent.

Abstract: A percent body fat measuring apparatus includes a first and a second electrodes with which a living body is brought into contact, a detection resistor of which one terminal is connected to the second electrode, signal generator which produces a measurement signal and applies a produced measurement signal between the first electrode and the other terminal of the detection resistor, level detector for detecting the level of a signal which develops between the terminals of the detection resistor and is an object of detection, and percent body fat computer for determining percent body fat on the basis of a result of detection operation performed by the level detector. A measurement signal produced by the signal generator is made analogous to a half-wave waveform, and the level detector detects the level of a waveform analogous to a half-wave of the signal to be detected.

Abstract: A method for reminding an individual to collect a urine specimen includes the steps of providing a pad or clip having a reminder area of a size such that the individual touches and discovers the pad, when preparing to urinate, and attaching the pad to the brief in the groin area, in a location where it will be encountered, and underneath an outer-garment, whereby the pad is hidden from view when in normal use, and whereby the individual, when preparing to urinate, will touch and discover the pad and thereby be reminded to collect the urine specimen. The pad or clip optionally is attached to the fly of a male brief or to the waistband of either a male or female brief. The invention accomplishes the reminder task by way of imposing behavior modification on the user by operating as a forced interruption to an otherwise established routine or ritual.

Abstract: A medical device for obtaining biopsy tissue samples is provided. The device includes a flexible outer tubular member having proximal and distal ends, and a flexible inner member slidably and preferably coaxially received within the outer tubular member. The inner member includes a flexible member adjacent the proximal end of the outer tubular member, a first spring section having proximal and distal ends and being oriented adjacent the distal end of the outer tubular member, and a second spring section therebetween. A retractable hollow needle member or other specimen collection device is coupled to the distal end of the first spring section.

Abstract: The disclosed methods and systems use measured values from applanation tonometry and pachymetry, and corneal curvature values to produce corrected values of intraocular pressure to diagnose and treat pressure related eye diseases.

Abstract: A system and method allow for inducing and measuring a consensual pupillary response of a subject. The system includes an induction device and a measuring device, the induction device being structured to generate at least one stimuli and to expose a primary eye of the subject to the stimuli. The measuring device of the system includes a monitoring mechanism structured to allow a consensual pupillary response to be detected, and an analysis mechanism to interpret the detected consensual pupillary response. The measuring device may also include a recording device and a display device, to allow recording and displaying of the detected consensual pupillary response, respectively. The method includes exposing the primary eye of the subject to the stimuli, monitoring and detecting the consensual pupillary response in the secondary eye of the subject, and analyzing the detected consensual pupillary response. The method may also include recording and displaying the detected consensual pupillary response.