Abstract: A protein which exhibits a therapeutic effect on inflammation and is useful for treating IL-1-mediated inflammatory diseases, particularly diseases of the joint.
Type:
Grant
Filed:
August 7, 1998
Date of Patent:
September 25, 2001
Assignee:
Amgen Inc.
Inventors:
Thomas C. Boone, Susan Hershenson, Michael P. Bevilacqua, David S. Collins