Abstract: A device for detecting the state of a heart on the basis of intracardial impedance measurement. The device has an impedance measuring unit, which has electrical terminals, configured to be electrically connected or to be connected to electrodes for delivering and detecting a current or voltage, and is implemented to ascertain an impedance on the basis of the dimension of the delivered current or voltage and the voltage drop caused by the current or the current caused by the voltage, as well as an analysis unit, which is connected to the impedance measuring unit and is implemented to derive a cardiac function parameter from a time curve of the impedance ascertained using the impedance measuring unit. The analysis unit analyzes the impedance curve assigned to a diastole and derives a cardiac function parameter characterizing the behavior of a heart during the diastole (filling phase of the ventricle).

Abstract: A floating physiological data acquisition system with expandable ECG and EEG. The data acquisition system for obtaining electrophysiological signals from a patient comprises a patient monitor and separate patient side acquisition units connectable to the patient monitor. Each of the patient side acquisition units comprises an analog-to-digital converter, a serial interface communicative towards a serial bus connecting the patient side data acquisition unit with the patient monitor, and a serial interface controller processor. Each of the patient side acquisition units further forms a part of a floating patient applied part of the data acquisition system.

Abstract: An intravenous pacemaker electrode has an electrode tip designed to release a drug, where the drug contains at least one of the active substances sirolimus, paclitaxel, everolimus, fibrin, rapamycin, and tacrolimus.

Abstract: An implantable active fixation lead includes an outer sheath, a protector member having a peripheral surface extending between its distal and proximal end surfaces with a helical groove formed in the peripheral surface, and a fixation helix integral with the outer sheath. The fixation helix includes a tip end engageable with body tissue and slidably engaged with the helical groove for relative translation and rotation. A longitudinal force on the lead firmly engages the protector member's distal end surface with the body tissue. With the fixation helix initially retracted proximally of the protector member's distal end surface and disengaged from the body tissue, upon application of torque to the outer sheath, the distal end surface of the protector member is moved proximally with respect to the fixation helix which, simultaneously, is extended distally beyond the distal end surface of the protector member to an extended position into engagement with the body tissue.

Abstract: An apparatus for applying a signal to a nerve for the treatment of a disorder includes a main electrode body of biocompatible dielectric material and having a concave upper surface and an opposite lower surface. The concave upper surface curves about an axis and has a curvature sized to receive a nerve within the concave surface with an axis of the nerve substantially parallel to an axis of the concave surface. An electrode contact of electrically conductive material is secured to the main electrode body and has an electrode contact surface exposed on the concave surface. The concave surface terminates at opposite first and second upper ends. The electrode contact has a first end near the first end of the concave surface. A secondary electrode body of biocompatible dielectric material is attached to the first upper end of the concave surface.

Abstract: An exemplary implantable device includes control logic to determine a base state atrio-ventricular delay (e.g., PV base or AV base) based on width of an atrial event (e.g., ?P or ?A) as measured during a patient base state and based on a value of a parameter ? that depends on the atrial event and control logic to determine an active state atrio-ventricular delay (e.g., PV active or AV active) based at least in part on a base state interval (e.g., DD base or AD base) measured during a patient base state and an active state interval (e.g., DD active or AD active) measured during a patient active state where such intervals extend from the end of a respective atrial event to the beginning of a respective ventricular QRS complex or a point within a respective ventricular QRS complex. Various other exemplary methods, devices, systems, etc., are also disclosed.

Abstract: Spring contact apparatus for an implantable medical device includes a plurality of nonconductive housing with each housing having a bore therethrough alignable with adjacent housing bores and assembled in spaced apart pairs with adjacent radial accesses to adjacent housing chambers. A plurality of electrically conductive garter springs are provided with the pairs of garter springs being disposed in corresponding adjacent housing chambers and each spring having a pigtail lead extending through a corresponding axis. The pairs of adjacent pigtail leads extending from adjacent axes are of sufficient length for a combined attachment to a corresponding pulse generator lead.

Abstract: In a method and a system of providing walking assistance and/or therapy to a person with impaired gait, electrical stimulation is applied to muscles of a leg that effect dorsiflexion and plantar flexion of the ankle of the leg. The timing of the electrical stimulation is determined from gait event signals developed from sensors under the heel and forepart of the foot of the other leg. In the method and the system, the electrical stimulation is enabled when the person is sensed to be active and is disabled when the person is sensed to be inactive. The method and the system are applicable to persons having unilateral or bilateral impairment of their walking ability.

Abstract: A catheter, in particular for insertion of heart-pacemaker- or ICD-electrodes into a patient's body, comprises a catheter wall and a reinforcement therein for stabilization of the catheter. The reinforcement is a profile element which is adjusted to the desired mechanical properties of the catheter in the axial and peripheral direction thereof.

Abstract: An exemplary implantable device includes control logic to determine a base state atrio-ventricular delay (e.g., PV base or AV base) based on width of an atrial event (e.g., ?P or ?A) as measured during a patient base state and based on a value of a parameter ? that depends on the atrial event and control logic to determine an active state atrio-ventricular delay (e.g., PV active or AV active) based at least in part on a base state interval (e.g., DD base or AD base) measured during a patient base state and an active state interval (e.g., DD active or AD active) measured during a patient active state where such intervals extend from the end of a respective atrial event to the beginning of a respective ventricular QRS complex or a point within a respective ventricular QRS complex. Various other exemplary methods, devices, systems, etc., are also disclosed.

Abstract: Implantable neural stimulation systems include an array of electrodes configured to apply one or more stimulation signals to a patient via one or more channels out of a multiplicity of channels during a stimulation frame and a signal processor configured to select the one or more channels for stimulation. The selection of the one or more channels is based on a probability associated with each channel within the multiplicity of channels.

Abstract: Methods of selecting a number of channels out of a multiplicity of channels of an implantable neural stimulation system for stimulation during a stimulation frame include obtaining a threshold corresponding to the stimulation frame, using the threshold to determine an adjusted amplitude corresponding to one or more channels within the multiplicity of channels, using the adjusted amplitudes to determine a probability for each of the one or more channels within the multiplicity of channels, providing a random number for each of the one or more channels within the multiplicity of channels, and selecting a number of channels within the one or more channels for stimulation during the stimulation frame. Each of the selected number of channels has a probability that is greater than the random number.

Abstract: Stimulation channel selection methods for an implantable neural stimulation system having a multiplicity of channels include computing a probability for each channel within the multiplicity of channels and selecting at least one of the channels for stimulation during a frame. The selecting of the at least one of the channels for stimulation during the frame includes selecting a channel, obtaining a random number, comparing the random number to the probability of the channel, and selecting the channel for stimulation if the probability of the channel is greater than the random number.

Abstract: Methods of selecting a number of channels out of a multiplicity of channels of an implantable neural stimulation system for stimulation during a stimulation frame include obtaining a threshold corresponding to the stimulation frame, determining an amplitude corresponding to each channel within the multiplicity of channels, comparing the amplitude corresponding to each of the channels within the multiplicity of channels to the threshold, and selecting each of the channels having amplitudes that exceed the threshold for stimulation during the stimulation frame.