Abstract: Chimeric polypeptides encoded by a DNA sequence having a first DNA subsequence coding for a fragment of at least one of the .alpha.- and/or .beta.-chain of the human interleukin-5 receptor, and a second DNA subsequence coding for the constant domains of a heavy- or a light-chain of a human immunoglobulin, or a fragment thereof are useful in treating illnesses with demonstrated eosinophilia.
Type:
Grant
Filed:
April 13, 1995
Date of Patent:
September 16, 1997
Assignee:
Hoffmann-La Roche Inc.
Inventors:
Rene Devos, Walter Fiers, Jose van der Heyden, Geert Plaetinck, Jan Tavernier