Patents Examined by Michael F Pepitone
  • Patent number: 11905351
    Abstract: A composition includes at least one siloxy-based (meth)acrylate monomer or prepolymer, at least one additional methacrylate monomer, UV, and Visible light blocking agents and one or more crosslinking agents. The final product results in a highly wettable material that possesses physical properties such as a low modulus of elasticity and high oxygen permeability without the need for a non-reactive solubilizing agent and that are free of cyclic and linear siloxanes.
    Type: Grant
    Filed: April 9, 2021
    Date of Patent: February 20, 2024
    Assignee: Envision Biomedical LLC
    Inventor: Jay Friedrich Künzler
  • Patent number: 11904030
    Abstract: The present invention relates to a dental composition comprising a radically polymerizable compound, a redox initiator system comprising one or more clathrate compounds comprising a host molecule and one or more guest molecules, wherein the host molecule is selected from cyclodextrines, crown ethers, cucurbituriles and calixarenes and the one or more guest molecules are reducing agents, and an oxidizing agent. Furthermore, the present invention relates to a use of the redox initiator system in a dental composition.
    Type: Grant
    Filed: March 5, 2019
    Date of Patent: February 20, 2024
    Assignee: DENTSPLY SIRONA INC.
    Inventors: Florian Szillat, Caroline Renn, Christian Scheufler, Jörg Brenneisen
  • Patent number: 11884964
    Abstract: The present disclosure provides systems and methods for making a hydrogel comprising a cell, cell nucleus, or one or more components derived from a cell or cell nucleus. A method for making a hydrogel may comprise providing a cell or cell nucleus, a first polymer, wherein the first polymer comprises a plurality of first crosslink precursors, each of the plurality of first crosslink precursors comprising an azide group; providing a second polymer, wherein the second polymer comprises a plurality of second crosslink precursors, each of the plurality of second crosslink precursors comprising an alkyne group; and crosslinking the first polymer and the second polymer via a reaction between a first section of the first crosslink precursors and a second section of the second crosslink precursors, thereby providing the hydrogel comprising the cell or cell nucleus.
    Type: Grant
    Filed: July 11, 2022
    Date of Patent: January 30, 2024
    Assignee: 10X GENOMICS, INC.
    Inventors: Joshua Delaney, Shalini Gohil, Christopher Hindson, Adam Lowe, Andrew D. Price, Joseph Francis Shuga
  • Patent number: 11886045
    Abstract: Described herein is a method for producing photochromic contact lenses, in particular, photochromic silicone hydrogel contact lenses. The method comprises a step of cast molding of a lens-forming composition including an iniferter to form an unprocessed contact lens having iniferter moieties covalently incorporated into its polymer matrix and a step of iniferter-induced graft-polymerization of a photochromic vinylic monomer to the polymer matrix only in its central region which is circular and concentric with the central axis of the unprocessed contact lens. The obtained photochromic contact lens has a central pupillary region that only can undergo a reversible color change upon exposure to UV/HEVL-radiation.
    Type: Grant
    Filed: November 3, 2021
    Date of Patent: January 30, 2024
    Assignee: Alcon Inc.
    Inventors: Yuan Chang, Junhao Ge, Steve Yun Zhang, Michelle Plavnik, Augustine Twum Kumi
  • Patent number: 11873280
    Abstract: Cross-linking agent(s), composition(s) made therefrom and use(s) thereof. For example, crosslinking agent(s) that are used to make composition(s) such as hydrogel material(s). Such materials are useful in the manufacture of biocompatible medical devices, for example, hydrogel materials having desirable physical properties for use as contact lense(s) and/or stimulating device(s).
    Type: Grant
    Filed: January 7, 2021
    Date of Patent: January 16, 2024
    Assignee: GL CHEMTEC VISION INC.
    Inventors: Musa Alhakimi, Gamil Alhakimi, Lisa Studnicki
  • Patent number: 11873361
    Abstract: An ophthalmic device for slowing, inhibiting or preventing myopia progression which is a polymerization product of a monomeric mixture comprising (a) greater than 50 wt. %, based on the total weight of the monomeric mixture, of one or more non-silicone-containing hydrophilic monomers; (b) one or more crosslinking agents; and (c) one or more red-light blocking compounds blocking greater than 5% to about 25% of red-light transmission through the ophthalmic device at a wavelength of from about 550 nm to about 800 nm, wherein the one or more red-light blocking compounds have one or more ethylenically unsaturated reactive end groups.
    Type: Grant
    Filed: June 9, 2022
    Date of Patent: January 16, 2024
    Assignee: BAUSCH + LOMB IRELAND LIMITED
    Inventors: Alok Kumar Awasthi, Kristen Rae Hovinga, Emily Abrams Gabriel, Kevin Jacob DeRyke, Jade J. Russell, James Anthony DiBella, Jr., Alana Ingham
  • Patent number: 11867874
    Abstract: The invention is generally related to an insert for being embedded in a silicone hydrogel contact lens. The insert is made of a crosslinked materials which are rigid in dry state at room temperature (from about 22° C. to about 26° C.), have a high oxygen permeability and a high refractive index in fully hydrated state, and can become softer at a temperature great than 32° C. Such materials are useful for making inserts in embedded contact lenses for correcting corneal astigmatism, presbyopia, and color blindness lenses and for imparting photochromic characteristics to the lenses. The invention is also related to a method for making embedded silicone hydrogel contact lenses comprising an insert of the invention therein and to embedded silicone hydrogel contact lenses comprising an insert of the invention therein.
    Type: Grant
    Filed: March 18, 2021
    Date of Patent: January 9, 2024
    Assignee: Alcon Inc.
    Inventors: Jing Cheng, Wei Liang, Steve Yun Zhang
  • Patent number: 11859051
    Abstract: Methods for synthesizing a polyamide having the optical absorber in the backbone of the polyamide may comprise: polymerizing polyamide monomers in the presence of an optical absorber selected from the group consisting of a polyamine optical absorber, a polyacid optical absorber, an amino acid optical absorber, and any combination thereof to yield the polyamide having the optical absorber in the backbone of the polyamide. Said polyamides having the optical absorber in the backbone of the polyamide may be useful in producing objects by methods that include melt extrusion, injection molding, compression molding, melt spinning, melt emulsification, spray drying, cryogenic milling, freeze drying polymer dispersions, and precipitation of polymer dispersions.
    Type: Grant
    Filed: June 30, 2020
    Date of Patent: January 2, 2024
    Assignee: Xerox Corporation
    Inventors: Valerie M. Farrugia, Mihaela Maria Birau
  • Patent number: 11844848
    Abstract: The present invention relates to a photocurable dental composition comprising a specific polymerization initiator system containing the combination of a photoinitiator compound and a coinitiator compound being a sulfinate compound or a sulfonate compound. The present invention also relates to the use of this polymerization initiator system in a photocurable dental composition.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: December 19, 2023
    Assignee: DENTSPLY SIRONA INC.
    Inventors: Florian Szillat, Maximilian Maier, Caroline Renn, Oliver Elsner, Joachim E. Klee, Jorg Kempter, Jacques Lalevee, Mariem Bouzrati-Zerelli, Julie Kirschner
  • Patent number: 11844847
    Abstract: A compound (A) is represented by the formula (1): wherein R1 is a hydrogen atom or an alkali metal atom, R2 is a hydrogen atom or an alkali metal atom, R3 is a hydrogen atom or a methyl group, Z is a divalent or trivalent organic group, and the lines consisting of a solid line and a broken line bonded to Z represent a single bond or a double bond.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: December 19, 2023
    Assignees: SUN MEDICAL CO., LTD., MITSUI CHEMICALS, INC.
    Inventors: Hideo Matsumura, Sayaka Miyamori, Takashi Yamamoto, Kazuhiko Yoshinaga, Shigeru Mio, Shinji Kiyono, Hina Suzuki
  • Patent number: 11844870
    Abstract: The present disclosure pertains to crosslinkable compositions and systems as well as methods for forming crosslinked compositions in situ, including the use of the same for embolizing vasculature including the neurovasculature within a patient, among many other uses.
    Type: Grant
    Filed: May 24, 2023
    Date of Patent: December 19, 2023
    Assignee: Arsenal Medical, Inc.
    Inventors: Jeffrey Groom, Craig Wiltsey, Quynh Pham, Nikhita Mansukhani, Courtney Guertin, Lee Core, Upma Sharma
  • Patent number: 11839664
    Abstract: Base material arrangements having at least two layers can accommodate the addition of antifungal material (nanofiller), such as in denture base resin without significantly compromising the mechanical properties and/or translucency of the base material arrangements. Antifungal agents such as nanosilver and nanozirconia can be used to modify a surface layer of the material arrangements, such as the denture base, to overcome certain known shortcomings of the modified materials, e.g., typical acrylic resins containing nanosilver and nanozirconia.
    Type: Grant
    Filed: July 31, 2023
    Date of Patent: December 12, 2023
    Assignee: Imam Abdulrahman Bin Faisal University
    Inventors: Mohammed Moustafa Ahmed Gad, Reem Abualsaud, Ahmed Mohamed Rahoma, Shaimaa Mohamed Said Fouda, Ahmad M. Al-Thobity
  • Patent number: 11828915
    Abstract: In one aspect, the present disclosure relates to a contact lens comprising a disclosed lubricious surface layer. In a further aspect, the lubricious surface layer comprises a polyacrylamide, e.g., a poly(N,N-dimethylacrylamide. In various aspects, the lubricious surface layer is formed at the surface of a contact lens. In a further aspect, the lens can be a hydrogel lens. In a further aspect, the lens can be a silicone hydrogel lens. The present disclosure also pertains to methods of forming the disclosed lubricious surface layers on a surface of a contact lens. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
    Type: Grant
    Filed: September 2, 2022
    Date of Patent: November 28, 2023
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Anuj Chauhan, Kuan-Hui Hsu, Yifan Yu
  • Patent number: 11828913
    Abstract: Described are silicone hydrogels that are more biocompatible than current ocular materials. The silicone hydrogels are formed from a reactive monomer mixture comprising: a mixture of hydroxyl substituted silicone containing components, at least one polyamide; and at least one hydrophilic monomer. The silicone hydrogels also display a desirable balance of properties, including clarity, oxygen permeability, wettability and desirable protein uptake.
    Type: Grant
    Filed: November 19, 2020
    Date of Patent: November 28, 2023
    Assignee: Johnson & Johnson Vision Care, Inc.
    Inventors: Azaam Alli, Alexander Guzman
  • Patent number: 11820850
    Abstract: Provided are polymer compositions made by a process comprising: (a) providing a first reactive composition containing: (i) a polymerization initiator that is capable, upon a first activation, of forming two or more free radical groups, at least one of which is further activatable by subsequent activation; (ii) one or more ethylenically unsaturated compounds; and (iii) a crosslinker; (b) subjecting the first reactive composition to a first activation step such that the first reactive composition polymerizes therein to form a crosslinked substrate network containing a covalently bound activatable free radical initiator, (c) combining the crosslinked substrate network with a second reactive composition containing one or more ethylenically unsaturated compounds; and (d) activating the covalently bound activatable free radical initiator of the crosslinked substrate network such that the second reactive composition polymerizes therein with the crosslinked substrate network to form a grafted polymeric network and a
    Type: Grant
    Filed: April 28, 2021
    Date of Patent: November 21, 2023
    Assignee: Johnson & Johnson Vision Care, Inc.
    Inventors: Brian Aitken, Charles Scales, Scott Joslin, Yong Zhang, Dola Sinha, Shivkumar Mahadevan, Patricia Martin, Fang Lu, Donnie Duis, Stephen C. Arnold
  • Patent number: 11807780
    Abstract: Disclosed is an aqueous coating composition including at least one latex polymer derived from at least one monomer copolymerized or blended with a rhamnolipid and/or sophorolipid biosurfactant, which in one embodiment is a mono-rhamnolipid. Also provided is an aqueous architectural coating composition including at least one latex polymer derived from at least one monomer copolymerized or blended with a biosurfactant, at least one pigment, and water.
    Type: Grant
    Filed: November 1, 2019
    Date of Patent: November 7, 2023
    Assignee: RHODIA OPERATIONS
    Inventors: Laura Gage, Denis Bendejacq, Homayoun Jamasbi
  • Patent number: 11802197
    Abstract: A composition for a food product storage container includes a polypropylene co-polymer, a tie additive, a color concentrate, and Ethylene vinyl alcohol. The ethylene vinyl alcohol may be between 3 and 10% by weight of the food product storage container. The composition further comprises small particle talc. The composition may be configured to be co-injection molded to form the food product storage container which may reduce an ingress of moisture and/or oxygen.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: October 31, 2023
    Assignee: NYPRO INC.
    Inventors: Aaron DuPont, Keith Poole, Doug Bengtson, Eric Paszkowski
  • Patent number: 11802182
    Abstract: The present invention generally relates to inherently wettable silicone hydrogel contact lenses having relatively high oxygen permeability, relatively high equilibrium water content and relatively low elastic modulus. The present invention is also related to a method for making such inherently wettable silicone hydrogel contact lenses.
    Type: Grant
    Filed: May 12, 2022
    Date of Patent: October 31, 2023
    Assignee: Alcon Inc.
    Inventors: Steve Yun Zhang, Daqing Wu, Junhao Ge, Richard Charles Breitkopf, Xinming Qian, Zach Munoz, Matthew D. Nelson, Augustine Twum Kumi, Weihong Lang, Ying Zheng, Feng Jing, Frank Chang
  • Patent number: 11793908
    Abstract: A bioanalogic implantable ophthalmic lens (“BIOL”) capable of replacing the natural crystalline lens (NCL) in its various essential functions after the NCL having been removed and BIOL implanted into the posterior eye chamber and placed into the capsular bag vacated from the NCL. At least the posterior surface of the lens has a convex shape and is made from a transparent flexible hydrogel material. At least the anterior and posterior optical surfaces are defined by rotation of one or more conic sections along the main optical axis and the surfaces defined by the rotation will include a plane perpendicular to the axis and conical surface symmetrical by the axis. A hydrogel implantable ophthalmic lens whose optical parameters can be optimized and/or customized by a controlled absorption of electromagnetic radiation resulting in a change of the refractive index of the irradiated hydrogel.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: October 24, 2023
    Assignee: MEDICEM INSTITUTE S.R.O
    Inventors: Vladimir Stoy, Vaclav Petrak, Miroslav Dudic
  • Patent number: 11793732
    Abstract: Dental material which comprises at least one compound of formula I, in which R1 is a linear, branched or cyclic aliphatic C1-C30 hydrocarbon radical or an aromatic C6-C30 hydrocarbon radical, wherein the aliphatic or aromatic hydrocarbon radical can be substituted or unsubstituted and wherein aliphatic hydrocarbon radicals can be interrupted by one or more urethane groups, ester groups, oxygen atoms and/or sulfur atoms; X, Y, Z independently of each other in each case are —COOR2, —CON(R3R4)—, an aromatic C6-C10 hydrocarbon radical or CN, wherein R2, R3, R4 in each case independently of each other is hydrogen, a linear, branched or cyclic aliphatic C1-C30 hydrocarbon radical or an aromatic C6-C30 hydrocarbon radical, wherein the aliphatic or aromatic hydrocarbon radical can be substituted or unsubstituted and wherein aliphatic hydrocarbon radicals can be interrupted by one or more oxygen atoms, and m is 2 or 3.
    Type: Grant
    Filed: February 3, 2021
    Date of Patent: October 24, 2023
    Assignee: Ivoclar Vivadent AG
    Inventors: Iris Lamparth, Norbert Moszner, Robert Liska, Christian Gorsche, Yohann Catel, Gernot Peer