Abstract: This invention provides a complex consisting essentially of prealbumin, retinol-binding protein, and a retinoid which binds to retinol-binding protein, wherein the concentration of retinoid in the complex is from about 2.times.10.sup.-5 M to about 10.sup.-10 M and the concentration of prealbumin and retinol-binding protein is sufficient to maintain the retinoid concentration from about 2.times.10.sup.-5 M to about 10.sup.-10 M. This invention also provides a composition for enhancing the growth of human B cells in culture which comprises an amount of the complex of this invention effective to enhance the growth of human B cells and a nutrient medium. This invention further provides a method of enhancing growth of human B cells in culture comprising growing the cells in culture in a growth medium containing a concentration of the complex effective to enhance growth of the cells.
Type:
Grant
Filed:
June 2, 1995
Date of Patent:
May 21, 1996
Assignee:
Sloan-Kettering Institute for Cancer Research
Abstract: Protein which acts as an inhibitor of the proliferation of endothelial ce which is obtainable from baby hamster kidney cells (ATCC CCL 10) and has a molecular weight between 60 and 100 kD in gel filtration under native conditions and is thermally stable at 60.degree. C., as well as a process for its isolation and its use in the treatment of diseases.
Type:
Grant
Filed:
August 25, 1992
Date of Patent:
February 15, 1994
Assignee:
Max Planck Gesellschaft zur Forderung der Wissenschaften E.V.
Abstract: A tubular composite structure for transmitting forces comprises a metal tubular core, preferably of aluminum, having a layer of structural metal adhesive on the exterior surface of the core. On top of the structural adhesive layer are alternating laminae of resin impregnated unidirectional reinforcing fibers, particularly carbon or graphite fibers, and of woven fiberglass, beginning with a layer of woven fiberglass followed by a lamina of resin impregnated continuous unidirectional reinforcing fibers and continuing in alternating fashion but ending with a final layer of resin impregnated continuous unidirectional reinforcing fibers, each successive layer of resin impregnated continuous unidirectional fibers having the fibers oriented at an angle of between about 5.degree. to 12.degree. with respect to the longitudinal axis of the metal tube and in opposite orientation with respect to the next preceding layer. The fibers in the woven fiberglass layer are oriented at 0.degree. and 90.degree.