Abstract: A system and method for treating hypotension in a mammal including a measuring device for measuring the blood pressure in a blood vessel having a wireless transmitter therein for emitting a signal when the measured blood pressure moves into a predetermined range. The system also includes an injection device fixed on the skin of a mammal, the injection device having a receiver for receiving the signal emitted from the wireless transmitter, a drug reservoir, a conduit for moving drug from the drug reservoir through the skin upon activation, and an activation device that causes the drug to move from the drug reservoir through the conduit and into the mammal upon receiving the signal emitted from the wireless transmitter.

Abstract: A sensor assembly includes a sensing element and an actuator. The sensing element measures a parameter associated with gas in an airway. The actuator actuates the sensing element to prevent contamination build up on the sensing element.

Abstract: In an embodiment, an electrical-line-noise canceller includes a phase detector, a phase lock loop, a zero-crossing detector, and an adaptive filter. The phase detector is configured to receive a composite input signal including an input neural signal combined with electrical line noise and to detect a phase of the electrical line noise. The phase lock loop is coupled to the phase detector and is configured to lock to the phase of the electrical line noise. The zero-crossing detector is coupled to the phase lock loop and is configured to detect zero crossings of an output of the phase lock loop. The adaptive filter is coupled to the zero-crossing detector and is configured to remove the electrical line noise from the composite input signal and output a filtered neural signal that is substantially similar to the input neural signal.

Abstract: A device for providing biofeedback information to a subject, including a receiver for receiving heart rate data from a sensor, said heart rate data corresponding to a human subject, a storage device for storing a time series of the received heart rate data, a display, and a processor that is programmed to enable access to the storage device and to perform actions including estimating an RSA strength of the subject's heart from the time series of the received heart rate data, calculating an accumulated RSA strength from a designated starting time until the present time, determining a motion by a virtual agent based on the accumulated RSA strength at the present time, said virtual agent being a graphical object or character that represents the subject, and displaying the motion of the virtual agent determined by said determining on the display.

Abstract: An intracerebral information measuring device which can be mounted on the head of a subject by simple surgery and which attains measurement of low invasion, high sensitivity, and high resolution is provided. An internally mounted unit is composed of a probe section to be inserted in the brain through a hole having a small diameter bored in the skull of the subject, and a head section integrated with the probe section and to be disposed between the skull and the scalp. The probe section includes an electrode for sensing an action potential. The head section includes a transmitter for wirelessly transmitting signals captured with the electrode to the outside. On the outside of the head, an external measuring unit for receiving the signal transmitted from the head section and reproducing the original signal is provided.

Abstract: An apparatus for assessing cardiovascular status of a mammal comprises a system for locally applying a pressure to an artery capable of restricting blood flow through said artery, a wideband external pulse transducer having an output and situated to measure suprasystolic signals proximate to said artery, and a computing device receiving said output for calculating vascular compliance values. The method described is particularly useful for determining cardiac output, assessing whether a pregnant female has preeclampsia or a patient has cardiac insufficiency, or assessing cardiac arrhythmias.

Abstract: A cardiovascular parameter such as cardiac output is estimated from a current pressure waveform data set without needing to directly measure blood flow or arterial compliance. The general shape of an input flow waveform over one beat-to-beat cycle is assumed (or computed), and then the parameters of a flow-to-pressure model, if not pre-determined, are determined using system identification techniques. In one embodiment, the parameters thus determined are used to estimate a current peripheral resistance, which is used not only to compute an estimate of the cardiovascular parameter, but also to adjust the shape of the input flow waveform assumed during at least one subsequent beat-to-beat cycle. Another embodiment does not require computation of the peripheral resistance and still another embodiment computes a flow estimate from an optimized identification of the parameters defining the assumed input flow waveform.

Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Abstract: A cuff of a pulse wave meter equipped with an arteriosclerosis degree judgment device has air bags for compressing a living body having a double structure along an artery including an avascularization air bag and a pulse-wave measuring air bag. Provided at outer circumferential sides of these air bags are a curler for integrally pressing these air bags against an upper arm, and an air bag for pressing the curler from the outer circumferential side. A member for suppressing vibrations is provided between a curler-compressing air bag and the pulse-wave measuring air bag, and suppresses propagation of vibrations from the curler-compressing air bag to the pulse-wave measuring air bag. The pulse wave meter measures a pulse wave based on changes in internal pressure in the pulse-wave measuring air bag while the avascularization air bag provides avascularization at the peripheral side.

Abstract: This invention relates to a method, system, and devices relating to quantitatively measuring regional lung tissue damage by combining the CT scan measurements of the mineral density deviations and/or mineral composition deviations in airway tissue, with the measurements of airflow lung function measurements.