Patents Examined by Michael L. Shippen
  • Process for the preparation of supported osmates
    Patent number: 6552234
    Abstract: The present invention discloses a process for the preparation of a novel heterogeneous osmate catalyst of the general formula (S—NR3)2OsO4.nH2O wherein S is a support, R is an alkyl group, n is the number of water molecules by reacting potassium osmate with supported quaternary ammonium species in an aqueous solvent.
    Type: Grant
    Filed: October 23, 2001
    Date of Patent: April 22, 2003
    Assignee: Council of Scientific and Industrial Research
    Inventors: Boyapati M. Choudary, Naidu S. Chowdari, Mannepalli L. Kantam, Kondapuram V. Raghavan
  • Process for catalytic hydroxylation of, saturated or unsaturated, aliphatic compounds
    Patent number: 6548718
    Abstract: A process for hydroxylating aliphatic compounds under catalytic distillation conditions to provide alcohols is provided. The aliphatic compound is contacted, in a distillation column reactor, with an oxidation catalyst and an oxidant under conditions effective to hydroxylate the aliphatic compound while maintaining at least a portion of the aliphatic compound in a liquid phase and separating the hydroxylated product from the un-reacted aliphatic compound in the distillation column reactor.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: April 15, 2003
    Assignee: Shell Oil Company
    Inventors: Brendan Dermot Murray, David Morris Hamilton, Jr.
  • Processes for the production of methyl dithiocarbazinate
    Patent number: 6545172
    Abstract: A process for the production of methyl dithiocarbazinate includes the steps of providing a mixture comprising hydrazine, solvent, carbon disulfide and base; adding methyl bromide to the mixture; cooling the reaction mixture; and recovering methyl dithiocarbazinate. The methyl dithiocarbazinate may be recovered by filtering the reaction mixture to yield a solid methyl dithiocarbazinate retentate and a liquid filtrate; acidifying the filterate with a mineral acid; and adding methyl isobutylketone to the acidified filterate.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: April 8, 2003
    Assignee: Bayer Corporation
    Inventors: Vidyanatha A. Prasad, Klaus Jelich, Dennis E. Jackman
  • Production of low-particulate bisphenol and use thereof in the manufacturing of polycarbonate
    Patent number: 6545187
    Abstract: Low-particulate dihydric aromatic compounds such as bisphenol-A that can be used in the synthesis of low-particulate polycarbonates are prepared by introducing into a desorber column containing a non-aggregate packing material an adduct of bisphenol and phenol and optionally a stripping gas. The column is maintained at an operating temperature that is sufficiently high and an operating pressure that is sufficiently low such that the adduct is distilled. The stream of phenol and the stripping gas is recovered from the top of the column. A second stream containing bisphenol that is substantially free of added particulate matter is recovered from the bottom of the column. This purified stream of bisphenol-A can further be used in a method of producing optical-grade polycarbonate.
    Type: Grant
    Filed: September 19, 2001
    Date of Patent: April 8, 2003
    Assignee: General Electric Company
    Inventors: Gaylord Michael Kissinger, Fang Christine Chen, James Cristopher Blubaugh, Darlene Hope Nance, Edward Brittain Stokes, Juan Rodriguez Ordonez, Jose M. Quintana
  • Method for producing bisphenol catalysts and bisphenols
    Patent number: 6534686
    Abstract: This disclosure relates to a method for producing and using catalysts in the production of bisphenols, and in particular to a method for producing catalysts which contain attached mercaptan promoters, and using these catalysts in the production of bisphenol-A and its derivatives.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: March 18, 2003
    Assignee: General Electric Company
    Inventors: Jimmy Lynn Webb, James Lawrence Spivack
  • Resorcinol production from the hydrolysis of meta-phenylenediamine
    Patent number: 6531637
    Abstract: A process for the preparation of resorcinol using the meta-phenylenediamine hydrolysis reaction is provided. A reactor vessel made of a suitable material such as zirconium or a zirconium alloy is used, thus resisting corrosion and formation of resinous materials.
    Type: Grant
    Filed: December 27, 2001
    Date of Patent: March 11, 2003
    Assignee: Indspec Chemical Corporation
    Inventors: Raj B. Durairaj, Gary A. Jesionowski
  • GABA and L-glutamic acid analogs for antiseizure treatment
    Patent number: 6525096
    Abstract: A compound of the formula wherein R1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R2 is hydrogen or methyl; and R3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.
    Type: Grant
    Filed: February 4, 1999
    Date of Patent: February 25, 2003
    Assignees: Northwestern University, Warner-Lambert Company
    Inventors: Richard B. Silverman, Ryszard Andruszkiewicz, Po-Wai Yuen, Denis Martin Sobieray, Lloyd Charles Franklin, Mark Alan Schwindt
  • Method for producing 3-l-menthoxypropane-1,2-diol
    Patent number: 6515188
    Abstract: A method for safely and efficiently producing high purity 3-l-menthoxypropane-1,2-diol and intermediates to be used in the method. As shown in the following reaction formula, 3-l-menthoxypropane-1,2-diol represented by the chemical formula (IV) is produced by adding l-menthol to a 1,2-epoxy-3-halogenopropane represented by the general formula (I) (wherein X represents a halogen atom) in an organic solvent in the presence of a Lewis acid, thereby producing a 1-halogeno-3-l-menthoxypropan-2-ol represented by the general formula (II), allowing the first intermediate to react with an alkali metal salt of an aliphatic carboxylic acid having from 1 to 5 carbon atoms to produce a 1-acyloxy-2-substituted-3-l-menthoxypropane represented by the general formula (III) and then hydrolyzing the second intermediate.
    Type: Grant
    Filed: April 4, 2002
    Date of Patent: February 4, 2003
    Assignee: Takasago International Corporation
    Inventors: Akira Amano, Teruyoshi Akiyama, Takashi Miura, Toshimitsu Hagiwara
  • Hydroformylation process utilizing multidentate phosphite ligands
    Patent number: 6515161
    Abstract: A hydroformylation process is disclosed which employs multidentate phosphite ligands in a catalyst composition. In particular, the ligands have heteroatom-containing substituents on the carbon attached to the ortho position of the terminal phenol group.
    Type: Grant
    Filed: August 30, 2000
    Date of Patent: February 4, 2003
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Kristina Ann Kreutzer, Wilson Tam, John Ronald Boyles, J Michael Garner
  • Process for the production of bisphenol A
    Patent number: 6512148
    Abstract: A process for the production of bisphenol A, including providing a melt of a crystalline adduct of bisphenol A and phenol, contacting the melt with a cation donating solid to neutralize the strong acid therewith, and then heating the melt to vaporize and remove phenol from the melt.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: January 28, 2003
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Susumu Yamamoto, Atsumi Kukidome, Makoto Nomura, Keiji Maehara, Kenji Nagahama
  • Method for removing butyl groups from butyl phenol compounds
    Patent number: 6512149
    Abstract: By bringing a p-butylphenol compound or m-butylphenol compound in the gas phase into contact with a solid acid catalyst, i.e., a silica-alumina catalyst or alumina catalyst while heating, butyl groups are removed from the butylphenol compound and at the same time, highly purified isobutylene is recovered.
    Type: Grant
    Filed: April 13, 2001
    Date of Patent: January 28, 2003
    Assignee: Honshu Chemical Industry Co., Ltd.
    Inventors: Kazuhiko Yao, Mitsuhiro Higashi, Kenji Ekawa
  • Process for continuous production of acetylenediol
    Patent number: 6506946
    Abstract: The present invention provides a process for producing an acetylenediol continuously by reacting a ketone with acetylene in the presence of an alkali catalyst, which process comprises continuously feeding, into a first-stage reactor, a reaction solvent, an alkali catalyst, a ketone and acetylene to give rise to a reaction, continuously introducing the reaction mixture into a second-stage reactor, and continuously feeding a fresh portion of the same ketone into the second-stage reactor to give rise to a reaction.
    Type: Grant
    Filed: June 12, 2002
    Date of Patent: January 14, 2003
    Assignee: Maruzen Petrochemical Co., Ltd.
    Inventors: Hideki Omori, Goro Sawada, Hideo Fukuda, Kazuhiro Imanishi, Tomohiko Sato
  • Process for the synthesis of (R)-1-(3,5-bis(trifluoromethyl)-phenyl)ethan-1-ol by asymmetric transfer hydrogenation
    Patent number: 6504066
    Abstract: The present invention is concerned with novel processes for the preparation of (R)-1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-ol. This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: January 7, 2003
    Assignee: Merck & Co. Inc.
    Inventors: Paul Devine, Hansen Karl
  • Method of making metal salts of 2,4,6-tri-t-butylphenol
    Patent number: 6504065
    Abstract: Reaction of a phenol with a metal salt of an alcohol produces a metal phenolate salt of a phenol. When a hindered phenol is used a hindered metal phenolate is produced. Such hindered metal phenolate salts are useful in driving the synthesis reaction of hindered phenol esters and phosphite esters to completion.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: January 7, 2003
    Assignee: General Electric Company
    Inventors: William Palmer Enlow, Gary Vincent Marlin
  • Process for the preparation of 2-acrylamido-2-methyl-1-propanesulfonic acid
    Patent number: 6504050
    Abstract: The present invention provides a process for the preparation of highly pure 2-acrylamido-2-methyl-1-propanesulfonic acid in high yield, with improved appearance, by the reaction of acrylonitrile with more than 98% sulfuric acid or oleum and liquefied isobutylene in presence of weak inorganic acids or organic sulfonic acids.
    Type: Grant
    Filed: March 13, 2002
    Date of Patent: January 7, 2003
    Assignee: Council of Scientific and Industrial Research
    Inventors: Prashant Purushottam Barve, Sunil Shankar Joshi, Ravindra William Shinde, Milind Yashwant Gupte, Chandrashekhar Narayan Joshi, Shrikant Madhukar Ghike, Raghavendra Venkatrao Naik, Rajendra Anantrao Kulkarni, Aruna Narayan Bote
  • Process to obtain xanthophyll concentrates of high purity
    Patent number: 6504067
    Abstract: An industrial process to obtain xanthophyll concentrates of high purity from plant extracts, comprising: refining the plant extracts by treating them with a diluted alkali, followed by treating them with a diluted organic or inorganic acid in order to eliminate impurities and undesirable components and obtaining a refined extract; saponifying the refined extract by means of a strongly alkali aqueous solution; treating the diluted saponified mass with a dilute organic or inorganic acid to adjust the pH to a value from 4 to 7, in order to separate a xanthophylls concentrate; and removing any remaining impurities by extracting them by means of hexane.
    Type: Grant
    Filed: November 24, 1999
    Date of Patent: January 7, 2003
    Assignee: Industrial Organica S.A. DE C.V.
    Inventors: Ricardo Montoya-Olvera, Juan-Roberto Elizondo-Mireles, Carlos-Javier Torres-Gómez, José-Odon Torres-Quiroga
  • D-mannitol and its preparation
    Patent number: 6503918
    Abstract: D-mannitol having a specific surface area of not less than about 1 m2/g is disclosed. The D-mannitol shows improved compressibility and is useful as an excipient.
    Type: Grant
    Filed: December 31, 2001
    Date of Patent: January 7, 2003
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Tomohiro Yoshinari, Fritz Schueckler, Norbert Poellinger, Shinji Maegata
  • Catalysts for hydrogenation of carboxylic acid
    Patent number: 6495730
    Abstract: Disclosed is a catalyst for hydrogenating a carboxylic acid, comprising an activated carbon having carried thereon an active metal species comprising ruthenium and tin, wherein the activated carbon is produced by subjecting a carbonaceous material to activation treatment using zinc chloride, followed by calcination. Also disclosed is a catalyst for hydrogenating a carboxylic acid, comprising an activated carbon having carried thereon an active metal species comprising ruthenium and tin, wherein the activated carbon, prior to having carried thereon the active metal species, exhibits specific pore characteristics wherein, especially, the pore volume with respect to pores each having a radius of from 10 to 100 Å is from 0.5 to 2.0 cm3/g.
    Type: Grant
    Filed: March 15, 2002
    Date of Patent: December 17, 2002
    Assignee: Asahi Kasei Kabushiki Kaisha
    Inventors: Mitsuo Konishi, Eizaburou Ueno
  • Process for the preparation of dihydroxydiphenylmethanes
    Patent number: 6492566
    Abstract: The present invention discloses an improved process for the preparation of dihydroxydiphenylmethanes by reacting phenol over a microporous alumino-silicate zeolite catalyst composite material in the presence of a condensing agent and a solvent at a temperature in the range of 5 to 200° C. for a period between 0.1 to 24 hours at autogeneous pressure and separating the dihydroxydiphenylmethanes by any conventional method.
    Type: Grant
    Filed: January 19, 2000
    Date of Patent: December 10, 2002
    Assignee: Council of Scientific and Industrial Research
    Inventors: Anand Pal Singh, Sharda Dagade
  • Dihydrotagetone alcohol and a method for preparation thereof from Tagetes minuta oil
    Patent number: 6492567
    Abstract: The present invention provides a novel dihydrotagetone alcohol of the general formula 1, wherein R is an alkyl or aryl group and a process for preparation thereof.
    Type: Grant
    Filed: October 24, 2001
    Date of Patent: December 10, 2002
    Assignee: Council or Scientific and Industrial Research
    Inventors: Bikram Singh, Virendra Prasad Joshi, Vijay Kumar Kaul