Abstract: A method is provided. The method includes placing a magnetic field viewing film over a region of tissue; inserting at least one of a medical device or a medical instrument comprising at least one magnetic element into the region of the tissue; and determining a location of at least one of the medical device or the medical instrument based on a visualization by the magnetic field viewing film of a magnetic field produced by the at least one magnetic element.

Abstract: A multispectral nevoscope that uses specific wavelengths in the visible and infrared spectrum of electromagnetic radiation to transilluminate a skin-lesion or a biological tissue or specimen for imaging and maps multispectral 2-dimensional images into 3-dimensional virtual space for providing 3-D distributions of pre-defined parameters representing the characteristic properties (such as melanin, hemoglobin and deoxyhemoglobin, etc.) of a skin lesion. Methods are disclosed for analyzing and using the characteristic distributions of specific parameters for detection and management of skin-cancers, or characterization of a biological tissue or specimen.

Abstract: The embodiments disclosed herein is a system for optical coherence tomographic imaging of turbid (i.e., scattering) materials utilizing multiple channels of information. The multiple channels of information may encompass spatial, angle, spectral and polarization domains. More specifically, the embodiments disclosed herein is related to methods and apparatus for utilizing optical sources, systems or receivers capable of providing (source), processing (system) or recording (receiver) a multiplicity of channels of spectral information for optical coherence tomographic imaging of turbid materials. In these methods and apparatus the multiplicity of channels of spectral information that can be provided by the source, processed by the system, or recorded by the receiver are used to convey simultaneously spatial, spectral or polarimetric information relating to the turbid material being imaged tomographically.

Abstract: A method includes performing first and second measurements with a turbid medium to be examined placed in a receiving volume of a device for examining the interior of turbid media. The second measurement is performed after a time interval has passed after the first measurement. Each of the first and second measurements includes subsequently irradiating the turbid medium with light from a light source from a plurality of different source positions and detecting light emanating from the turbid medium in a plurality of different detection positions for each source position, and storing the detected values as measurement results. The method also includes detecting inhomogeneities in the interior of the turbid medium by using the measurement results of one of the first and second measurements as a reference and the measurement results of the respective other of the first and second measurements to determine deviations from the reference.

Abstract: An embodiment in accordance with the present invention provides a method for non-invasively determining the functional severity of coronary artery stenosis. The method includes gathering patient-specific data related to concentration of a contrast agent within a coronary artery of a patient using a coronary computed tomography angiography scan (CCTA). The patient-specific data is used to calculate a patient-specific transluminal attenuation gradient for the coronary artery of the patient. The patient specific transluminal attenuation gradient is used to determine an estimate of a coronary flow velocity, pressure gradient, loss coefficient, coronary flow reserve, and/or fractional flow reserve for the patient. Coronary flow velocity, pressure gradient, loss coefficient, coronary flow reserve, and fractional flow reserve can then be used to estimate the functional severity of coronary artery stenosis.

Abstract: Medical diagnostic ultrasound imaging is performed with a multi-dimensional transducer array and an imaging system for planar scanning. The elements of the array may be distributed on a periodic grid with aperiodic shifts in position. When a one-dimensional array is formed on the array, the aperiodic shifts better distribute acoustic energies, reducing peaks in side lobes. Using a layered structure of switches underneath the acoustic elements, side lobes may be further reduced. The switches are used for interconnecting elements to form macro elements of the one-dimensional aperture on the multi-dimensional array. The switches are distributed on a grid corresponding to the desired imaging frequency. The acoustic elements are distributed with a finer pitch. The finer pitch allows formation of the macro elements for the one-dimensional aperture where the edges of the macro elements have fewer or no periodic patterns.

Abstract: An embodiment in accordance with the present invention provides a method for non-invasively determining the functional severity of arterial stenosis in a selected portion of an arterial network. The method includes gathering patient-specific data related to concentration of a contrast agent within an arterial network using a coronary computed tomography angiography scan (CCTA). The data can be gathered under rest or stress conditions. Estimation of a loss coefficient (K) can be used to eliminate the need for data gathered under stress. The data is used to calculate a transluminal attenuation gradient (TAG). The data may be corrected for imaging artifacts at any stage of the analysis. TAFE is used to determine an estimate of flow velocity. Once velocity is determined, pressure gradient, coronary flow reserve, and/or fractional flow reserve can be determined through a variety of methods. These estimates can be used to estimate functional severity of stenosis.

Abstract: Apparatus and methods are described including acquiring a plurality of image frames of a portion of a subject's body. At least one of the image frames is designated as a baseline image frame, a shape of the portion in the first baseline image frame being designated as a baseline shape. A non-baseline-shape image frame is deformed, such that the shape of the portion becomes more similar to the baseline shape of the portion than when the portion in the non-baseline-shape image frame is not deformed. A composite image is formed that is of higher clarity with respect to anatomy of the portion, relative to each of the acquired image frames, by averaging at least the deformed non-baseline-shape image frame with the baseline image frame. The composite image is displayed on a display. Other applications are also described.

Abstract: For a three-dimensional region including a treatment target site of a patient, a puncture needle scanning region R1 having a slice thickness d1 is set with reference to a cross section (a puncture cross section) including an insertion direction of a puncture needle. Subsequently, in the y-direction substantially perpendicular to the puncture cross section, two treatment target scanning regions R2 (R21 and R22) each being adjacent to the puncture needle scanning region R1 and having a slice thickness d2 are set. Then, based on volume data in the puncture needle scanning region R1 acquired by first three-dimensional scan with ultrasound waves and volume data in the treatment target scanning regions R2 acquired by second three-dimensional scan performed at a lower volume rate than the first three-dimensional scan, image data is generated for the purpose of supporting puncture.

Abstract: According to one embodiment, an ultrasonic diagnosis apparatus includes an ultrasonic probe, an ultrasonic transmission/reception unit which generates echo signals associated with scan planes by transmitting and receiving ultrasonic waves to and from an object via the ultrasonic probe, an image data generating unit which generate tomogram data respectively corresponding to the scan planes based on the echo signals, a contour line extraction processing unit which extracts contour lines of a specific region from the plurality of tomograms, a contour line processing unit which generates curves respectively corresponding to the extracted contour lines, and a surface image generating unit which generates one-dimensional brightness trains on the curves from the tomograms and generates a surface image expressing the surface unevenness of the specific region with brightness changes by arraying the brightness trains in accordance with the positions of the corresponding scan planes.

Abstract: Timing in a medical imaging system. The system comprises a magnetic resonance imaging (MRI) subsystem and a non-MRI subsystem. Operation of the non-MRI subsystem involves a timing signal within a radio frequency (RF) cabin of the MRI subsystem. Basing each non-MRI subsystem timing signal on a time base common between the MRI subsystem and the non-MRI subsystem. The non-MRI subsystem can be a medical imaging subsystem. The non-MRI medical imaging subsystem can be a positron emission tomography (PET) subsystem. Each non-MRI subsystem timing signal that based on the common time base can be created using the same model of equipment used for creating timing signals in the MRI subsystem. At least one stage of the non-MRI subsystem timing signal based on the common time base can be created using the same equipment used for creating timing signals in the MRI subsystem.

Abstract: A tissue-image creating unit creates a tissue image including depth values by volume rendering from three-dimensional tissue data stored in a three-dimensional data storage unit. A blood-flow data converting unit scatters a blood flow in three-dimensional blood-flow data stored in the three-dimensional data storage unit into particles, and converts the three-dimensional blood-flow data into three-dimensional particle data. A blood-flow image creating unit creates a blood-flow image including depth values from the three-dimensional particle data. A composite-image creating unit then creates a composite image by coordinating the order of rendering particles and tissue based on the depth values of respective pixels included in the tissue image and the depth values of respective particles included in the blood-flow image. A display control unit then controls display of the composite image so as to be displayed in order onto a monitor included in an output unit.

Abstract: The present invention improves projection displays of volume data. Using the Minimum Intensity Projection (MinIP), fluid filled regions or other regions of hyporeflective tissue are displayed. By limiting the projection to partial volumes within the volume, differences in the scattering intensity within specific regions are isolated. In this way, hyperreflectivity of weakly scattering tissue can be assessed.

Abstract: An imaging system comprises a catheter having a lumen, a rotatable imaging probe within the catheter lumen including a distal transducer and first and second conductors coupled to the transducer, and a coupler that couples the rotatable first and second conductors to non-rotatable third and fourth conductors, respectively. The coupler includes a rotary capacitive coupler.

Abstract: Methods and systems for patient alignment for nuclear medicine imaging are provided. One method includes activating a proximity sensor system associated with imaging detectors of the diagnostic imaging system, wherein the imaging detectors are in an L-mode configuration. The method also includes initiating movement of a patient table of the diagnostic imaging system and using a sensed proximity of a patient on the moving patient table by the proximity sensor system to automatically adjust a height of the patient table on which the patient is supported to a patient table height scanning position.

Abstract: An embodiment analyzes a body part of a patient, which patient is perfused with a contrast agent that is capable of circulating within the patient and of being substantially immobilized on a biological target. An embodiment of a corresponding system provides an echo signal that is indicative of a response over time to an interrogation signal of the body part, fits the echo signal with a time model function that models an evolution over time of the contrast agent in the body part, the time model function including a combination of a circulation function that models the circulation of the contrast agent and a decay function that models a decay of the echo signal from the immobilized contrast agent, and estimates at least one kinetics indicator of the contrast agent from the time model function.

Abstract: A real-time signal processing technique for ultrasonic imaging of tissue vibrations for localizing the source of a bruit in a 2D image with respect to the anatomy and/or for obtaining simultaneous information about vibrations and the underlying blood flow. The bruit can be quantitatively assessed using an ensemble of ultrasound echoes. Signal processing enables estimation of wall displacement and the display of time-resolved vibration spectrum. Vibrations are detected and color-coded according to their amplitude and frequency and overlaid on the B-mode and/or color-flow image in real time. Proposed vibration imaging algorithms use data acquired during conventional ultrasonic color-flow imaging and the clutter signal, normally suppressed in color-flow imaging, to detect and characterize tissue vibrations. Three vibration imaging algorithms based on parametric modeling of vibrations and other criteria distinguish between clutter, blood flow, and vibrations.

Abstract: A pharyngeal ultrasound guide (PUG) to be placed inside the pharynx which allows the transmission of ultrasonic waves from a ultrasonic probe placed therein into the structures of the pharynx, throat, and major vessels; the technique of acquisition of the ultrasonic images and Doppler measurements using such a device; and the procedures which may be performed using the images.

Abstract: A wiring board electrically connected to a back side of an ultrasound transmitting/receiving section that transmits/receives ultrasound includes a rigid circuit board included in a stiff portion, and a wrapping portion extending out from the rigid circuit board (stiff portion), and a plurality of drive wirings electrically connected to the wiring board are inserted into a wiring insertion portion of a housing with the plurality of drive wirings wrapped and bundled by the wrapping portion.

Abstract: A system and method for assessing tissue health based on the viscoelastic properties of the tissue. Surface waves are induced in the tissue and their propagation characteristics are then measured. The tissue viscoelastic properties are then determined from the surface wave measurements using a surface model.