Abstract: A cuff includes a fluid bladder, an outer cover that contains the fluid bladder toward one end portion, a surface fastener, and another surface fastener. The outer cover includes, in an area of the outer cover that includes a region in which the other surface fastener is provided, a first wide portion in which the width of the outer cover is greater than a width of an area of the outer cover that includes a region in which the surface fastener is provided. The other surface fastener includes a second wide portion in which the width of the other surface fastener is greater than the width of the surface fastener. The cuff can be fitted to a measurement area with certainty.

Abstract: A device and method can monitor or trend a patient's respiration rate measurements according to the time of day. The device, which may be implantable or external, collects and classifies respiration rate measurements over time. The trended information about particular classes of respiration rate measurements is then communicated to a remote external device, which in turn provides an indication of heart failure decompensation. Examples of classes of respiration rate measurements include a daily maximum respiration rate value, a daily minimum respiration rate value, a daily maximum respiration rate variability value, a daily minimum respiration rate variability value, and a daily central respiration rate value. These respiration rate measurements can be further classified into daytime or nighttime respiration rate measurements.

Abstract: This disclosure relates to systems and/or methods for subtracting in the current domain an output current primary signal from a primary sensor from an output current reference signal from a reference sensor to produce a frequency output signal indicative of the difference between the output current primary signal and the output current reference signal.

Abstract: A micromachined fluid flow regulating device is disclosed comprising a fluid flow channel, at least one flow orifice formed in the channel, defining an inlet portion of the channel upstream of the flow orifice, an outlet portion of the channel downstream of the flow orifice, the fluid having a flow direction from the inlet portion to the outlet portion of the channel. At least one piston is arranged upstream of the flow orifice, movably suspended in the channel by a spring means such that the piston is movable by the fluid in the flow direction of the fluid, towards the flow orifice, to regulate a fluid flow through the flow orifice. The disclosure further relates to the use of a micromachined flow regulating device in a breath analysis device and to a method of fabricating a flow regulating device.

Abstract: A region of skin, other than the fingertips, is stimulated. After stimulation, an opening is created in the skin (e.g., by lancing the skin) to cause a flow of body fluid from the region. At least a portion of this body fluid is transported to a testing device where the concentration of analyte (e.g., glucose) in the body fluid is then determined. It is found that the stimulation of the skin provides results that are generally closer to the results of measurements from the fingertips, the traditional site for obtaining body fluid for analyte testing.

Abstract: A blood pressure measurement system that non-invasively determines an individual's blood pressure can include a noninvasive blood pressure sensor having an optical sensor and a motion sensor. The optical sensor can provide a photoplethysmograph signal obtained from a patient to a processor. The motion sensor can provide a motion signal to the processor responsive to motion of the patient. In one embodiment, the processor calculates or estimates the blood pressure of the patient based on the photoplethysmograph signal and the motion signal. Advantageously, the system can obtain this blood pressure measurement without an occlusive cuff, thereby reducing patient discomfort. In other implementations, the processor calculates a blood pressure-related parameter from the photoplethysmograph and motion signal. The processor can occasionally trigger an occlusive cuff measurement as this parameter changes, thereby reducing the frequency of occlusive cuff measurements.

Abstract: A blood pressure measuring apparatus which measures a blood pressure in a step of gradually changing a cuff pressure adapted to press an artery, includes: a pulse wave detecting unit; a pulse wave interval measuring unit; a waveform information storing unit; a change trend calculating unit; a waveform information comparing unit; and a determining unit which, when first two of the pulse waves, which are successively detected at different cuff pressures, satisfy a predetermined condition: that a magnitude relationship between the amplitudes of the first two of the pulse waves is consistent with the change trend of the first two of the pulse waves; that the pulse wave interval between the first two of the pulse waves is within a predetermined range; and that the waveform information of the first two of the pulse waves approximately coincide with each other, determines that the amplitude of latter one of the first two of the pulse waves is to be used for calculating the blood pressure value.

Abstract: Provided is a method for estimating blood pressure using a variable characteristic ratio. In the method, a pressure wave detected at a measurement body part of a subject is obtained to calculate a characteristic ratio of the subject based on a correlation between the characteristic ratio used to determine blood pressure at a measurement body part and the shape of the pressure wave detected at the measurement body part. The blood pressure at the measurement body part of the subject is estimated using the calculated characteristic ratio.

Abstract: A computerized method of analyzing measurements obtained from the gastrointestinal tract of subject comprising the steps of providing an ingestible capsule (20) having a sensor (22, 23, 24) for measuring a parameter of the gastrointestinal tract of a subject, having a subject ingest (118) the capsule, recording (130) measurements from the sensor as the capsule passes through the gastrointestinal tract of the subject, transmitting (131, 122) the measurements to a processor (31), conditioning (132) the measurements to provide data as a function of a time interval, plotting (133) the data on a display (32), providing a query (205, 216, 234), on the display, receiving input (207a or 207b, 218a or 218b, 237a or 237b) from a user in response to the query, setting a marker (50-53) on the plot (40) at a location as a function of the input, and determining (238) a capsule transit time for a selected portion of the gastrointestinal tract as a function of the location of the marker.

Abstract: A chemical extraction apparatus has absorbent material for absorbing or adsorbing volatile chemicals from a breath of a user. The chemical extraction apparatus is positioned within such that breaths from the user flow over the absorbent material thereby causing volatile chemicals in the breaths to absorb or adsorb into the absorbent material. The absorbent material is then analyzed to determine the amount of chemicals absorbed or adsorbed into the absorbent material. Based on such analysis, various diseases or conditions can be detected or diagnosed.

Abstract: The apparatus includes: a detection section for detecting a time period during which an operator is making preparations prior to beginning a driving operation; an adjustment section for adjusting a determination criterion for determining a state of attention of the operator during a driving operation, which calculates an eye fixation related potential of the electroencephalogram signal of the operator measured at least in the time period by using the measured oculomotor signal of the operator, and which adjusts the determination criterion based on the calculated eye fixation related potential; a determination section for calculating an eye fixation related potential from the electroencephalogram signal and the oculomotor signal of the operator measured after beginning the driving operation, which determines a state of attention of the operator during the driving operation based on the calculated eye fixation related potential and the adjusted determination criterion; and an output section for acting to call a

Abstract: An airway adaptor that measures the concentration of at least one of a specific component and the flow rate of a supply gas and a return gas. The airway adapter may include a tube having a flow path in which the supply gas and the return gas passes. The tube may include a first end having a first aperture for guiding the supply gas into the flow path, and second end having a second aperture for guiding the return gas. Further, the airway adapter may include a measurement device operable to measure at least one of the supply gas and the return gas in the air flow path and a partial shielding disposed at the first aperture and structured to shield a portion of the air flow path. The supply gas may be a respiratory gas and the return gas may be inhaled or exhaled breath of a person.

Abstract: This disclosure relates to systems and/or methods for subtracting in the current domain an output current primary signal from a primary sensor from an output current reference signal from a reference sensor to produce a frequency output signal indicative of the difference between the output current primary signal and the output current reference signal.

Abstract: Methods and apparatus for providing data processing and control for use in verifying the stability of sensor sensitivity of an analyte sensor.

Abstract: The invention relates to detection of anomalies related to a measurement of the hypnotic level of a subject. In order to detect when a measure indicative of the hypnotic level of a subject is anomalous either due to a medical reason or due to an interference, the measure is monitored and state information indicative of the activity of the autonomous nervous system of the subject and drug effect information indicative of the hypnotic drug effect in the subject are employed to check whether the measure fulfills a predetermined consistency condition requiring that the measure changes consistently with at least one of the drug effect information and the state information. An anomaly, indicative of an abnormal change in the measure, is detected when the measure fails to fulfill the predetermined consistency condition.

Abstract: A blood pressure cuff includes a first bladder having a width, and a length transverse to the width. The blood pressure cuff also includes a second bladder connected to the first bladder and a port fluidly connected to at least one of the first and second bladders.

Abstract: Some embodiments provide a wearable fitness monitoring device including a motion sensor and a photoplethysmographic (PPG) sensor. The PPG sensor includes (i) a periodic light source, (ii) a photo detector, and (iii) circuitry determining a user's heart rate from an output of the photo detector. Some embodiments provide methods for operating a heart rate monitor of a wearable fitness monitoring device to measure one or more characteristics of a heartbeat waveform. Some embodiments provide methods for operating the wearable fitness monitoring device in a low power state when the device determines that the device is not worn by a user. Some embodiments provide methods for operating the wearable fitness monitoring device in a normal power state when the device determines that the device is worn by a user. Some embodiments provide methods for using response characteristics of the user's skin to adjust a gain and/or light emission intensity of the heart rate monitor.

Abstract: Improved tourniquet apparatus for measuring a patient's limb occlusion pressure includes an inflatable tourniquet cuff for encircling a limb at a location and to which a tourniquet instrument is releasably connectable.

Abstract: An introducer is provided for introducing a sensor into the body of a patient. The introducer connects to a sensor hub. When the sensor hub and introducer are connected, the introducer needle is exposed. When the sensor hub and introducer are disconnected, a needle cover and the needle move with respect to each other so that the needle cover substantially covers the needle, protecting a user from being injured by the needle.

Abstract: Generally, methods, devices, and systems for generating a hybrid analyte level output are provided. The uncompensated analyte levels lag in time with respect to the lag-compensated analyte levels, and the hybrid analyte level output tracks between the uncompensated analyte levels and the lag-compensated analyte levels according to predetermined criteria.