Abstract: A system for determining a location of an electrode of a medical device (e.g., a catheter) in a body of a patient includes a localization block for producing an uncompensated electrode location, a motion compensation block for producing a compensation signal (i.e., for respiration, cardiac, etc.), and a mechanism for subtracting the compensation signal from the uncompensated electrode location. The result is a corrected electrode location substantially free of respiration and cardiac artifacts. The motion compensation block includes a dynamic adaptation feature which accounts for changes in a patient's respiration patterns as well as intentional movements of the medical device to different locations within the patient's body. The system further includes an automatic compensation gain control which suppresses compensation when certain conditions, such as noise or sudden patch impedance changes, are detected.

Abstract: A method for monitoring an intrabody region of a patient. The method comprises intercepting electromagnetic (EM) radiation from the intrabody region in a plurality of EM radiation sessions during a period of at least 6 hours, calculating a dielectric related change of the intrabody region by analyzing respective the intercepted EM radiation, detecting a physiological pattern according to said dielectric related change and outputting a notification indicating the physiological pattern.

Abstract: A system and a method of using dual-energy absoptiometry to estimate visceral fat metrics and display results, preferably as related to normative data. The process involves deriving x-ray measurements for respective pixel positions related to a two-dimensional projection image of a body slice containing visceral fat as well as subcutaneous fat; at least some of the measurements being dual-energy x-ray measurements, processing the measurements to derive estimates of metrics related to the visceral fat in the slice; and using the resulting estimates.

Abstract: A biopsy device includes a probe, a holster, and a tissue sample holder for collecting tissue samples. The probe includes a needle and a hollow cutter. The tissue sample holder includes a housing having a plurality of chambers that are configured to receive a plurality of strips connected by at least one flexible member. The flexible member is configured to permit the strips to pivot relative to each other such that the strips can shift between a flat configuration and a arcuate configuration. The tissue sample holder is rotatable to successively index each chamber to the cutter lumen such that tissue samples may be collected in the strips. The strips may be removed from the tissue sample holder and placed in a tissue sample holder container for imaging of tissue samples.

Abstract: The present invention provides a hood for an ultrasonic endoscope and an ultrasonic endoscope that prevent a body wall from getting into close contact with an observation window at a time such as when an ultrasonic transducer is brought into close contact with the body wall. In a hood for an ultrasonic endoscope to be attached to the ultrasonic endoscope, a notch is formed at a front edge of the hood, and a front edge corner at an observation window side along the notch is provided as an eaves-shaped part. The eaves-shaped part protrudes in front of the observation window, and when an ultrasonic transducer is brought into close contact with the body wall, the eaves-shaped part lies between the body wall and the observation window, thereby preventing the body wall from getting into close contact with the observation window.

Abstract: Embodiments associated with combined magnetic resonance angiography and perfusion (MRAP) and nuclear magnetic resonance (NMR) fingerprinting are described. One example apparatus repetitively and variably samples a (k, t, E) space associated with an object to acquire a set of NMR signals that are associated with different points in the (k, t, E) space. Sampling is performed with t and/or E varying in a non-constant way. The apparatus includes a signal logic that produces an NMR signal evolution from the NMR signals and a characterization logic that characterizes a resonant species in the object as a result of comparing acquired signals to reference signals. The apparatus includes an MRAP logic that simultaneously performs MR angiography and produces quantitative perfusion maps. A multi-factor MR bio-imaging panel is produced from a combination of the data provided by the MRAP and NMR fingerprinting. Diagnoses may be made from the multi-factor MR bio-imaging panel.

Abstract: An ultrasound system performs duplex colorflow and spectral Doppler imaging, with the spectral Doppler interrogation performed at a sample volume location shown on the colorflow image. The colorflow image is displayed in a color box overlaid on a co-registered B mode image. A color box position and steering angle processor analyzes the spatial Doppler data and automatically sets the color box angle and location over a blood vessel for optimal Doppler sensitivity and accuracy. The processor may also automatically set the flow angle correction cursor in alignment with the direction of flow. In a preferred embodiment these optimization adjustments are made automatically and continuously as a user pauses at points for Doppler measurements along a length of the blood vessel.

Abstract: A method for tissue assessment includes ablating tissue at a site within a body of a living subject using an invasive probe applied to the site. At a first stage in ablation of the tissue, first measurements are made of scattered light intensities from the site at a plurality of different wavelengths. At a second stage in the ablation of the tissue, subsequent to the first stage, second measurements are made of the scattered light intensities from the site at the plurality of different wavelengths. Progress of the ablation is assessed by computing different, respective measures of change in the scattered light intensities at the different wavelengths occurring between the first and second measurements, and comparing the respective measures.

Abstract: In accordance with exemplary embodiments of the present disclosure, device and method can be provided which can facilitate imaging of biological tissues, e.g., luminal organs in vivo, using optical techniques. The exemplary device can include different designs an features of one or more catheters, which can illuminate the tissues, and collect signals from the inside of the lumen. In another exemplary embodiment according to the present disclosure, a balloon-catheter can be provided with the flexible neck, which can absorb most of the bending. According to still another exemplary embodiments of the present disclosure, a balloon-catheter tethered capsule can be provided, and according a yet further exemplary embodiment, a structured balloon design can be provided with one or more protuberances, thus enabling imaging of the structures in close contact, e.g., without compressing of the tissue.

Abstract: Apparatus and methods which enable the stimulation of neurons oriented in all directions within a biological structure using applied magnetic fields.

Abstract: A method for generating an ultrasound image includes receiving an image frame comprising consecutive ultrasound scan lines obtained using a rotating ultrasound imaging arrangement and determining at least a first cross-correlation value and a second cross-correlation value for each of a plurality of the scan lines. For each individual scan line of the plurality of scan lines, the first cross-correlation value comprises a cross-correlation coefficient between a first subframe comprising a plurality of consecutive scan lines including the individual scan line and a second subframe comprising a plurality of scan lines shifted from the first subframe by a first integer value. The second correlation value comprising a cross-correlation coefficient between the first subframe and a third subframe comprising a plurality scan lines shifted from the first subframe by a second integer value that is different from the first integer value.