Abstract: System for filtering cardiac signals. The system includes: cardiac terminals (10a-d) adapted to collect cardiac electrophysiological potentials from a plurality of cardiac electrodes (1a-d) placed at respective cardiac locations in or on an individual (99) and a processor device (40) adapted to process one or more input signals, which are based on the collected electrophysiological potential(s). The processing includes running an adaptive filter algorithm on one or more signals based on the input signals. The adaptive filter algorithm is arranged to calculate estimated noise component(s) of the signals and arranged to subtract the estimated noise component(s) from the signals. In this way a cardiac signal is derived where the noise has been significantly reduced.

Abstract: A wellness evaluation system may determine, based on data generated by a first set of sensors powered by one or more batteries of one or more ear-wearable devices, that a user of the one or more ear-wearable devices is currently in an environment that includes human-directed communication signals. If so, a second set of sensors may be activated such that the one or more batteries provides an increased amount of power to the second set of sensors. Furthermore, the wellness evaluation system may determine based on data generated by the second set of sensors, whether the user has satisfied a target level of a wellness measure. If the user has not satisfied the target level of the wellness measure, the wellness evaluation system may perform an action to encourage the user to perform one or more activities to increase an achieved level of the wellness measure.

Abstract: The present application relates to an optical system (1) comprising a plurality of optical components, a pulse generating arrangement (3) configured to generate a treatment pulse along a treatment pulse optical path through said optical components, said pulse generating arrangement also being configured to generate a probe pulse along a probe pulse optical path extending through said optical components, a sensor (8) configured to generate information indicative of an optical characteristic of said probe pulse that has passed along said probe pulse optical path through said optical components, and a controller (5) configured to control said pulse generating apparatus (3) to selectively emit said treatment pulse along said treatment pulse optical path (2), in dependence on the information generated by the sensor (8).

Abstract: The present disclosure relates generally to pacing of cardiac tissue, and more particularly to adjusting delivery of His bundle or bundle branch pacing in a cardiac pacing system to achieve synchronized ventricular activation. A leadless pacing device (LPD) may include a plurality of electrodes comprising a bundle pacing electrode leadlessly connected to the housing, which may be implanted proximate to or in the His bundle or bundle branch of the patient's heart. An electrical pulse generator may generate and deliver electrical His-bundle or bundle-branch stimulation pulses using the bundle pacing electrode based on sensing one or both of an atrial event and a ventricular event. The LPD may receive communication from another implantable device, such as a subcutaneously implanted device, and deliver His-bundle or bundle-branch pacing in response to the communication.

Abstract: This disclosure describes, among other embodiments, systems and related methods for selecting electrode combinations to be used during nerve pacing procedures. A first set of electrode combinations of a nerve pacing system, such as a phrenic nerve pacing system for diaphragm activation, may be mapped (or tested) to determine the location of the electrode combinations relative to a target nerve. Once the general location of the target nerve is known, a more localized second set of electrode combinations may be tested to determine the most suitable electrode combinations for nerve stimulation. At various stages of the mapping process, electrode combinations that are non-optimal may be discarded as candidates for use in a nerve pacing procedure. The systems and methods described herein may allow for the selection of electrode combinations that are most suitable for stimulation of the left and right phrenic nerves during diaphragm pacing.

Abstract: Stimulation lead includes an elongated lead body having distal and proximal ends and wire conductors extending therebetween. The stimulation lead also includes a lead paddle having a multi-dimensional array of electrodes positioned along a contact side of the lead paddle. The electrodes are electrically coupled to the wire conductors. The lead paddle includes a paddle body and a conductor organizer disposed within the paddle body. The conductor organizer has multiple channels extending along the lead paddle. The channels receive the wire conductors and retain the wire conductors in a designated arrangement with respect to the lead paddle. The conductor organizer has openings to the channels. The wire conductors extend through the openings and are terminated to the respective electrodes.

Abstract: A system for treating disordered breathing of a human being includes an implantable transvenous stimulation lead having at least one stimulation electrode and a sensor configured to detect activity level of the human being. The system includes an energy source, a pulse generator and circuitry, the circuitry operative to receive a signal indicative of the activity level of the human being from the sensor, wherein the circuitry is configured to cause the energy source and the pulse generator to deliver spaced apart stimulation signals to the at least one stimulation electrode while the activity level of the human being is sufficiently low to be indicative of sleep. Spaced apart stimulation pulses from the electrode are configured to extend a duration of a time of at least one breath being defined as the time from an onset of inhalation to the onset of inhalation of a successive breath.

Abstract: An implantable medical device for treating breathing disorders such as central sleep apnea wherein stimulation is provided to the phrenic never through a transvenous lead system with the stimulation beginning after inspiration to extend the duration of a breath and to hold the diaphragm in a contracted condition.

Abstract: An interface structure for detachably interfacing a surgical robot arm to a surgical instrument, the interface structure comprising a main body; and a drive transfer element comprising a first portion and a second portion, the first portion being releasably engageable with a portion of the surgical robot arm and the second portion being releasably engageable with a portion of the surgical instrument; the drive transfer element being movable relative to the main body so as to enable transfer of drive between the surgical robot arm and the surgical instrument.

Abstract: An implantable direct-current electrode assembly (20, 120) has two implantable electrodes (30; 40) and a control circuit (50), to which the first and the second electrodes (30; 40) are electrically connected. The control circuit (50) is designed to establish a potential difference between the two electrodes (30; 40), so that a direct current (55) can flow between the two electrodes (30; 40). One of the electrodes (30) is a coil electrode with a maximum length that is pre-determined by the distance between the tricuspid valve and the end of the right ventricle lying opposite the tricuspid valve and the pulmonary valve. The counter-electrode (40) can be a coil electrode for the coronary sinus, or a plate electrode that can be attached to the exterior of the left ventricle.

Abstract: Various embodiments are described herein for a system and a method for assessing a risk of ventricular arrhythmias for a patient. For example, the method may comprise receiving ECG data obtained from the patient; analyzing the ECG data to detect abnormal QRS peaks; determining the risk of ventricular arrhythmias for the patient based on the detected abnormal QRS peaks; and providing an indication of the risk of ventricular arrhythmias for the patient. The system may be configured to perform this method.

Abstract: A needle tip mounted on a skin care device and the skin care device are provided to prevent a proximity effect. The needle tip includes a case, a holder disposed in the case and reciprocating in a vertical direction, and a plurality of needle electrodes disposed in the holder, a current being applied to the plurality of needle electrodes. The plurality of needle electrodes include a first group of needle electrodes and a second group of needle electrodes to which the current is applied at mutually different times.

Abstract: A transcranial electrical stimulation device includes a base, a first electrode, and a second electrode. The base includes a center portion, a first end portion, a second end portion, and a first surface. The first end portion and the second end portion are angled relative to the center portion. The first electrode includes a first conductive cup and a first post. The second electrode includes a second conductive cup and a second post.

Abstract: An apparatus for treating venomous bites and stings of poisonous snakes, insects and other types of poisonous vectors with a titrated dose of electrons. The unit is small and easily portable and requires on a 9-vold DC battery for power. It does not require a lot of expertise to use. A bi-metallic switch provides for a limited (and calculated) dose delivery of electrons. The venom desensitizer destabilizes and de-organizes toxic metalloproteinases. This occurs through several physiological and chemical phenomena. It addresses oxidative stress occurring from bite trauma as well as venom toxins without causing negative side effects other than a brief electrical shock.

Abstract: Apparatus and methods are described, including a catheter (20) configured to be placed inside a blood vessel of a subject. A first impeller (28) is disposed on the catheter, and a second impeller (28) is disposed on the catheter, proximally to the first impeller. A support structure (160) is disposed upon the catheter such that a longitudinal center of the support structure is disposed between the first and second impellers, the support structure being configured to support an inner wall of the blood vessel in an open configuration in a region between the first and second impellers. Other applications are also described.

Abstract: A system for monitoring a cardiac health of a subject by measuring an indicator of the cardiac health of a subject is disclosed. In some embodiments, the system comprises a wearable device configured for being detachably attached to a thoracic region of the subject, the subject being ambulatory or at rest, a communication device and a network server. In one embodiment, the wearable device is configured for sensing and communicating at least one of the electrocardiogram signals and sensor data representing the one or more clinically relevant health parameters of the subject to the communication device. Further, the communication device is configured for communicating at least the electrocardiogram signal and the sensor data representing the one or more clinically relevant health parameters of the subject to the network server using a first communication channel and a second communication channel.

Abstract: In a first aspect, a method of controlling an appliance is provided that includes (1) employing a wearable monitor to detect a biometric parameter of a user; (2) communicating biometric parameter information from the wearable monitor to a mobile telephone of the user; (3) determining if the biometric parameter information indicates that a value of the biometric parameter has crossed a predetermined threshold; and (4) if the value of the biometric parameter has crossed the predetermined threshold, employing the mobile telephone to direct an appliance to change between a first operating condition and a second operating condition. Numerous other aspects are provided.

Abstract: A method includes generating a plurality of primary beams from a laser beam, and generating, from a primary beam one or more secondary beams. The method also includes focusing the first secondary beam to a first focal region in the target tissue and the second secondary beam to a second focal region in the target tissue. The first focal region and the second focal region can be located at different depths in the target tissue.

Abstract: An improved laser-therapy device for the treatment of acupuncture points, which comprises: a control unit; laser emitting means associated to said control unit; means for generating an emission signal, which are functionally associated to said control unit and to said laser emitting means; and means for modulating said emission signal, which are designed to generate a modulated signal, wherein said modulated signal derives from a first square-wave modulation at a frequency of 100 Hz combined with a second square-wave modulation at a frequency of between 1 and 2 Hz, characterized in that a third square-wave modulation at a frequency of between 50 and 200 Hz is provided, combined, respectively, with said first and second modulations, characterized in that a third square-wave modulation at a frequency of between 5 and 20 Hz is provided, combined, respectively, with said first and second modulations.

Abstract: A method for reducing left ventricular volume, which comprises identifying infarcted tissue during open chest surgery; reducing left ventricle volume while preserving the ventricular apex; and realigning the ventricular apex, such that the realigning step comprises closing the lower or apical portion of said ventricle to achieve appropriate functional contractile geometry of said ventricle in a dyskinetic ventricle of a heart.