Patents Examined by Michail Belyavskkyi
  • Mammalian expression vectors and uses thereof
    Patent number: 8187836
    Abstract: The present invention features nucleic acids for recombinant protein expression in mammalian cell culture. The episomal vectors of the invention promote high protein production in mammalian cells expressing the SV40 T Ag or Epstein-Barr virus nuclear antigen (e.g., COS7 or HEK293-6E cells). The methods and systems are useful, for example, in pharmaceutical drug development and cloning, especially for the production of antibodies.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: May 29, 2012
    Assignee: Abbott Laboratories
    Inventor: Chung-ming Hsieh