Patents Examined by Michele C. Flood
  • Patent number: 8945639
    Abstract: The present invention relates to compositions (including medicaments and nutritional products) for use in the prevention or treatment of Inflammatory Bowel Disease. Such compositions comprise a therapeutically effective amount of a soluble fiber derivable from fruit of the Musa spp. The soluble fiber may in particular be derived from plantains or bananas.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: February 3, 2015
    Assignee: Provexis (IBD) Limited
    Inventor: Jonathan Rhodes
  • Patent number: 8883228
    Abstract: This invention provides a composition for heart disease comprising extracts from raw herbs of 80.0-97.0% Radix Salviae Miltorrhizae, 1.0-19.0% Panax Notoginseng and 0.1-1.0% Borneol and its active ingredients. This invention also provides a method for preparing said composition and the active ingredients of the composition. Finally, this invention provides various uses of said compositions and the active ingredients.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: November 11, 2014
    Assignee: Tasly Pharmaceutical Group Co. Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Zhixin Guo, Zhengliang Ye, Yan Liu
  • Patent number: 8852652
    Abstract: Provided, among other things, is a method of treating or ameliorating an indication of mucosal or adjacent tissue comprising periodically applying to mucosa at or adjacent to disease affected tissue a rinse comprising: an effective amount of appropriate composition of herbal bioactive comprising active(s) of one or more of Sambucus nigra, Centella asiatica or Echinacea purpurea; an antimicrobially effective amount of a quaternary ammonium surfactant; and optionally a polymer or mixture of polymers effective to coat said tissue and entrap said extract(s).
    Type: Grant
    Filed: December 3, 2012
    Date of Patent: October 7, 2014
    Assignee: Izun Pharmaceuticals, Inc.
    Inventors: Zvi G. Loewy, William Zev Levine, Aron J. Saffer
  • Patent number: 8563051
    Abstract: Herbal extracts composition suitable for weight management in mammals is disclosed. The composition comprises a mixture of Garcinia extract, Green tea extract, Green coffee extract and Banaba extract. The method of reducing weight, and treating diabetes in mammals involve oral administration of the composition. The invention further relates to a method of producing and standardizing the individual extract useful for human health.
    Type: Grant
    Filed: December 23, 2011
    Date of Patent: October 22, 2013
    Assignee: InQpharm Sdn Bhd
    Inventors: Philip Samuel, Fred Pescatore
  • Patent number: 8563054
    Abstract: An anti-inflammatory agent which includes an oil-soluble licorice extract, prepared by subjecting at least one of a leguminous plant of the genus Glycyrrhiza and a water extraction residue of a leguminous plant of the genus Glycyrrhiza to an extraction treatment with an organic solvent and which has at least one effect selected from an inhibitory effect on hyaluronidase activity, an inhibitory effect on hexosaminidase release (i.e., inhibitory effect on histamine release), an inhibitory effect on platelet aggregation, and an inhibitory effect on phospholipase A2 activity.
    Type: Grant
    Filed: January 15, 2010
    Date of Patent: October 22, 2013
    Assignee: Maruzen Pharmaceuticals Co., Ltd.
    Inventors: Yasuo Miyake, Ito Yoko
  • Patent number: 8529907
    Abstract: Provided is a method for improving day photopic vision and/or cone-derived visual field and visual function in a subject suffering from a retinal disease or trauma including administering to the subject a pharmaceutically effective amount of crude Dunaliella powder. Also provided is a method for improving night vision and/or rod derived visual field in a subject suffering from a retinal disease including administering to the subject a pharmaceutically effective amount of crude Dunaliella powder. A pharmaceutical composition for improving day vision and/or visual field in a subject suffering from a retinal disease including crude Dunaliella powder is also provided.
    Type: Grant
    Filed: April 27, 2009
    Date of Patent: September 10, 2013
    Assignees: Nikken Sohonsha Corporation, Tel Hashomer Medical Research Infrastructure and Services Ltd.
    Inventors: Michael Belkin, Aviv Shaish, Dror Harats, Ygal Rotenstreich
  • Patent number: 8486464
    Abstract: This invention provides compositions comprising extracts of Radix Salviae Miltiorrhizae, Radix Notoginseng and Borneol. Said compositions comprise notoginsenoside R1 and ginsenoside Rg1 which are active components for therapeutic applications. This invention also provides a method of preparation of the said compositions and a method of identification and determination of the amount of individual effective components of said compositions. Finally, this invention provides various uses of the compositions.
    Type: Grant
    Filed: July 31, 2002
    Date of Patent: July 16, 2013
    Assignee: Tasly Pharmaceutical Group Co. Ltd.
    Inventors: Xijun Yan, Naifeng Wu, Zhixin Guo, Zhengliang Ye, Yan Liu
  • Patent number: 8367072
    Abstract: A composition for a medicinal or health effect of a treatment of liver fat and body fat, a reduction of blood pressure, an increase of the energy expenditure rate, a reduction of inflammatory C-reactive proteins and a reduction of plasma aminotransferase enzymes, comprising an effective amount of fucoxanthin alone or in combination with pomegranate seed oil, a pharmaceutically acceptable salt, a prodrug thereof, or a salt of the prodrug; and a method of using the same. The fucoxanthin may be used in pure form, or as a component of a brown marine vegetable extract.
    Type: Grant
    Filed: December 10, 2007
    Date of Patent: February 5, 2013
    Assignee: Polifenoles Naturales, S.L.
    Inventor: Svetlana Ramazonova
  • Patent number: 8357422
    Abstract: The technology provides a multi-purpose dietary supplement that includes, in nutritionally effective amounts for humans, an orally ingestible combination of antioxidants, naturally-occurring substances and extracts of naturally-occurring substances. The naturally-occurring substances and extracts of naturally-occurring substances include at least: finely divided silica hydride; a polyphenol; ginkgo biloba leaf extract; rhodiola rosea root; bacopa monniera extract; a glutathione precursor; a phytoalexin; a bioflavonoids; CoQ10 and a phospholipid.
    Type: Grant
    Filed: July 2, 2010
    Date of Patent: January 22, 2013
    Assignee: RBC Life Sciences, Inc.
    Inventor: Clinton Howard
  • Patent number: 8343557
    Abstract: The present invention relates to synergic compositions incorporating agents for reducing cellulite and unaesthetic appearance associated therewith which comprise a base matrix constituted by conjugated linoleic acid (CLA), grape seed extract, beta-glucan, organic calcium and dry extract of pine bark together with complementary synergic agents of the matrix. The invention also relates to the use of such compositions and formulations containing said compositions.
    Type: Grant
    Filed: October 27, 2009
    Date of Patent: January 1, 2013
    Assignee: STARGATE—Produtos Farmacêuticos, Dietéticos e Nutricionais, Lda.
    Inventor: Edoardo Messora
  • Patent number: 8343554
    Abstract: The present invention relates to formulations comprising combinations of analgesic/anti-inflammatory, immunomodulating and cartilage-reconstructing agents in particular comprising saligenig, boswellic acid, procyanidins, N-acety-glucosamine and either glucoronic acid or glucoronolactone, for the treatment of rheumatoid arthritis and, more generally, of arthritis conditions.
    Type: Grant
    Filed: January 6, 2004
    Date of Patent: January 1, 2013
    Assignee: Indena S.p.A.
    Inventor: Ezio Bombardelli
  • Patent number: 8329227
    Abstract: The present invention provides formulas for producing compositions for the structural/functional nutritional support for those who struggle with poor focus, concentration and/or memory. In addition, the present invention provides compositions comprising nutritional/botanical factors helpful to those who subjectively experience transient mental fatigue or poor cognitive function. The compositions of this invention consist primarily of the following ingredients B-complex vitamins, antioxidants, minerals, phosphatidyl serine (PS), choline, dimenthyl-aminoethanol (DMAE), docosahexaenoic acid (DHA), L-pyroglutamic acid, as well as herbal extracts from Bacopa monniera, Vinca minor, and Huperzia serrata. The present invention also relates to the administration of these compounds to alleviate mental fatigue or poor cognitive function.
    Type: Grant
    Filed: December 7, 2004
    Date of Patent: December 11, 2012
    Assignee: Factor Nutrition Labs, LLC
    Inventor: Kyl L. Smith
  • Patent number: 8324177
    Abstract: The invention provides saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monoterpenoid moieties are attached. The mixtures and compounds have properties related to the regulation of apoptosis and cytotoxicity of cells and exhibit potent anti-tumor effects against a variety of tumor cells.
    Type: Grant
    Filed: June 14, 2011
    Date of Patent: December 4, 2012
    Assignee: Research Development Foundation
    Inventors: Charles J. Arntzen, Mary E. Blake, Jordan U. Gutterman, Joseph J. Hoffmann, Gamini S. Jayatilake, David T. Bailey
  • Patent number: 8318213
    Abstract: A composition comprising an effective amount of Cissus quadrangularis to reduce fat and cause weight loss in a mammal. Such compositions have beneficial activity principally in controlling weight gain and obesity.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: November 27, 2012
    Assignee: Gateway Health Alliances, Inc.
    Inventor: Julius Enyong Oben
  • Patent number: 8287923
    Abstract: Green tea polyphenol compositions and methods of their use are provided. Certain aspects provide methods for modulating expression of one or more autoantigens using the disclosed green tea polyphenol compositions. Representative green tea polyphenols include, but are not limited to (?)-epigallocatechin-3-gallate. Other aspects provide methods for treating autoimmune disease.
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: October 16, 2012
    Assignee: Medical College of Georgia Research Institute, Inc.
    Inventors: Stephen D. Hsu, Carol A. Lapp, George S. Schuster
  • Patent number: 8277822
    Abstract: A liquid or semi-solid formulation of botulinum toxin for the preparation of a medicament intended to treat a disorder characterized by bladder spasms (e.g. urinary incontinence due to unstable bladder or unstable detrusor sphincter, voiding complications due to detrusor overactivity or unstable detrusor sphincter, urinary retention secondary to spastic sphincter or hypertrophied bladder neck and neurogenic bladder dysfunction secondary to Parkinson's disease, spinal cord injury, stroke or multiple sclerosis or characterized by a spasm reflex), wherein said medicament is for administration by infusion into the bladder or by other methods that do not involve injection into the bladder wall.
    Type: Grant
    Filed: May 29, 2008
    Date of Patent: October 2, 2012
    Assignee: Ipsen Biopharm Limited
    Inventors: Chris Dott, John Batchelor, Pierre Bernard D'Arbigny, Roland Cherif-Cheikh
  • Patent number: 8268782
    Abstract: Disclosed is both a method for preparing a plasminogen and a method for preparing a reversibly inactive acidified plasmin by activating the plasminogen. The prepared plasminogen is typically purified from a fraction obtained in the separation of immunoglobulin from Fraction II+III chromatographic process and eluted at a low pH. The prepared plasmin is isolated and stored with a low pH-buffering capacity agent to provide a substantially stable formulation. The reversibly inactive acidified plasmin may be used in the administration of a thrombolytic therapy.
    Type: Grant
    Filed: March 6, 2009
    Date of Patent: September 18, 2012
    Assignee: Grifols Therapeutics Inc.
    Inventors: James F. Rebbeor, Jonathan S. Strauss, Jeffrey A. Yuziuk
  • Patent number: 8252845
    Abstract: Resveratrol has been reported to have hypolipidemic properties. We investigated whether resveratrol and its analogs: pterostilbene, piceatannol and resveratrol trimethyl ether, would activate the peroxisome proliferator-activated receptor alpha (PPAR?) isoform. This nuclear receptor is proposed to mediate the activity of lipid-lowering drugs such as the fibrates. The four stilbenes and ciprofibrate (positive control) were evaluated for the activation of endogenous PPAR? in H4IIEC3 cells transfected with a luciferase gene reporter construct. Pterostilbene demonstrated the highest induction of PPAR?; the maximal response to pterostilbene was similar to that obtained with the hypolipidemic drug, ciprofibrate.
    Type: Grant
    Filed: February 1, 2012
    Date of Patent: August 28, 2012
    Assignees: The United States of America, as represented by the Secretary of Agriculture, The University of Mississippi
    Inventors: Agnes M. Rimando, Dennis R. Feller, Wallace H. Yokoyama
  • Patent number: 8197863
    Abstract: A method of using hop acids for increasing food and energy uptake from feed by livestock is described which includes delivering the hop acids for oral ingestion to the animals by mixing the acids with livestock feed. The acids are mixed with the feed in an amount to inhibit certain types of undesirable bacteria in the livestock's digestive system, thereby increasing the production of propionate and lactate and decreasing the production of methane gas.
    Type: Grant
    Filed: May 27, 2010
    Date of Patent: June 12, 2012
    Assignee: John I. Haas, Inc.
    Inventor: John Paul Maye
  • Patent number: 8188108
    Abstract: A pharmaceutical composition comprising an analgesic or analgesic combination and a stool softener is disclosed. The analgesic is selected from morphine, meperidine, fentanyl, hydromorphone, oxymorphone, oxycodone, hydrocodone, methadone, propoxyphene, pentazocine, levorphanol, codeine, acetaminophen and combinations of these analgesics. The composition is formulated for oral administration as a liquid or solid dosage form for immediate, slow, delayed or sustained-release characteristics.
    Type: Grant
    Filed: May 31, 2011
    Date of Patent: May 29, 2012
    Assignee: Branded Products for the Future
    Inventors: Ricardo Mayo-Alvarez, Ronny McNeil