Patents Examined by Migual Escallon
  • Methods of detecting periodic paralysis in horses
    Patent number: 5356777
    Abstract: Methods for detecting the mutation in the horse adult skeletal muscle sodium channel alpha-subunit gene that causes hyperkalaemic periodic paralysis in horses is provided based on a mutation in the sodium channel region IV, S.sub.3.
    Type: Grant
    Filed: October 1, 1992
    Date of Patent: October 18, 1994
    Assignee: University of Pittsburgh
    Inventors: Eric P. Hoffman, Sharon J. Spier, Jeffrey A. Rudolph, Glen Byrns, Domenico Bernoco
  • Phenytoin derivatives
    Patent number: 5306617
    Abstract: A phenytoin derivative represented by formula (I) ##STR1## wherein Ph denotes a phenyl group,X denotes --O--, --NH-- or --CH.sub.2 --,Y denotes --CO-- or --CH.sub.2 --,Z denotes a hydrogen atom or a hydroxyl group,M denotes a salt-forming cation, andm and n are each an integer of 0 to 8 and m+n is at least 2.Said compound is useful to produce a phenytoin-labelled DNA or RNA probe. When using such a probe, DNA or RNA in the specimen can be detected with high sensitivity.
    Type: Grant
    Filed: August 13, 1991
    Date of Patent: April 26, 1994
    Assignee: Fujirebio Inc.
    Inventors: Takafumi Uchida, Hiroshi Ishikawa, Koichi Koyama, Yoshihiro Kurano, Yoshiaki Uchida