Patents Examined by Mina Haghighatian
  • Functionalized environmentally benign nanoparticles
    Patent number: 10278395
    Abstract: This invention is directed to the preparation and applications of internally and/or externally functionalized environmentally benign nanoparticles (EbNPs), which are produced by a three step procedure: (1) synthesis of native EbNPs, (2) functionalization with active agents, and (3) additional surface property customization via one or more modifier(s).
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: May 7, 2019
    Assignee: North Carolina State University
    Inventors: Orlin D. Velev, Alexander P. Richter
  • Pharmaceutical composition comprising nanoparticles, preparation and uses thereof
    Patent number: 10265406
    Abstract: The present application relates to a pharmaceutical composition comprising biocompatible nanoparticles or nanoparticles aggregates which allows the appropriate delivery of said biocompatible nanoparticles or nanoparticles aggregates to a target site in a subject in need thereof. The composition indeed allows an accumulation of the biocompatible nanoparticles or nanoparticles aggregates it comprises into the targeted tissue of the subject of at least 4 milligram (mg) nanoparticles or nanoparticles aggregates per gram (g) of targeted tissue when at least 0.1 g of the pharmaceutical composition per kilogram (kg) of body weight is injected intravenously (IV) or intraarterially (IA) into said subject.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: April 23, 2019
    Assignee: NANOBIOTIX
    Inventors: Agnes Pottier, Laurent Levy, Matthieu Germain
  • Modular biocompatible materials for medical devices and uses thereof
    Patent number: 10266408
    Abstract: A metal-organic compound containing polymer matrix includes a polymer and a three-dimensional metal-organic framework includes a polydentate organic linker. The metal-organic compound containing polymer matrix is configured to continuously produce nitric oxide when exposed to a physiological fluid including a nitric oxide-releasing compound via a catalytic reaction catalyzed by the three-dimensional metal-organic framework.
    Type: Grant
    Filed: January 15, 2015
    Date of Patent: April 23, 2019
    Assignee: COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Melissa M. Reynolds, Benjamin P. Reynolds
  • Aprepitant oral liquid formulations
    Patent number: 10251891
    Abstract: A liquid pharmaceutical compositions comprising Aprepitant is preferably prepared as an oral suspension dosage form for the prevention and control of acute and delayed chemotherapy induced nausea and vomiting, and/or for prevention of postoperative nausea and vomiting.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: April 9, 2019
    Assignee: InnoPharma, Inc.
    Inventors: Udaya Toti, Shyamprasad Mukundan, Sasank Chaitanya Kunadharaju, Tushar Hingorani, Kumaresh Soppimath, Satish Pejaver, Navneet Puri
  • Methods for reducing particulates in the air
    Patent number: 10252210
    Abstract: Methods for reducing particulates in the air are disclosed. In some embodiments, the method comprises spraying a composition having an effective amount of a zwitterionic polymer, a compressed gas propellant, and an aqueous carrier in to the air. The composition agglomerates particulates upon contacting particulates in the air thereby reducing particulates in the air.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: April 9, 2019
    Assignee: The Procter & Gamble Company
    Inventors: Chisomaga Ugochi Nwachukwu, Alan Edward Sherry
  • Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto
    Patent number: 10251394
    Abstract: This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, compositions containing such molecules, and processes of using such molecules and compositions against such pests. These molecules and compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).
    Type: Grant
    Filed: January 18, 2017
    Date of Patent: April 9, 2019
    Assignee: Dow AgroSciences LLC
    Inventors: Thomas Barton, Xin Gao, Jim Hunter, Paul R. LePlae, Jr., William C. Lo, Joshodeep Boruwa, Raghuram Tangirala, Gerald B. Watson, John Herbert
  • Particulate materials
    Patent number: 10251881
    Abstract: Embodiments of the invention relate to particles of active substances, methods for preparing the particles, formulations containing the particles, and metered dose inhalers containing such particles or formulations. In one embodiment, a composition of an aerosol formulation is provided and contains a particulate active substance of non-micronized, solid particles having a mass median aerodynamic diameter of less than 10 ?m suspended in a hydrofluorocarbon fluid vehicle at a concentration within a range from about 0.2% w/v to about 5% w/v. The aerosol formulation exhibits a flocculation volume of about 85% or greater about 1 minute after mixing the particulate active substance and the hydrofluorocarbon fluid vehicle. The particulate active substance contains an alkaloid ergotamine, pharmaceutically acceptable salts thereof, analogues thereof, or derivatives thereof.
    Type: Grant
    Filed: March 2, 2017
    Date of Patent: April 9, 2019
    Assignee: Nektar Therapeutics
    Inventors: Andreas Kordikowski, Stephen Ernest Walker, Peter York
  • Composition with insect repellent activity
    Patent number: 10251825
    Abstract: A composition comprising a compound having a Formula I: wherein T is derivative of a terpene and R is a derivative of a neurotransmitter amino acid. Pharmaceutical formulations for topical use as insect repellents including the terpenes and terpene esters in form of the pharmaceutically acceptable salt or base are provided. A process for preparing the composition and the formulations are also provided.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: April 9, 2019
    Inventors: Iryna Kravchenko, Mariia Nesterkina, Sergiy Lozovsky
  • Fungicidal active compound combinations
    Patent number: 10244755
    Abstract: Safeners for herbicides are suitable for increasing the microbicidal activity of fungicides.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: April 2, 2019
    Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Reiner Fischer, Peter Dahmen, Ulrike Wachendorff-Neumann
  • Fruity odorant
    Patent number: 10246402
    Abstract: The present invention concerns the use as perfuming ingredient (of the fruity type) of a compound of formula in the form of any one of its stereoisomers or of a mixture thereof, and wherein R1 represents a C1-3 alkyl or alkenyl group, R2 represents a methyl or ethyl group, R3 represents a C1-4 alkyl or alkenyl group, and the compound (I) has from 8 to 12 carbon atoms.
    Type: Grant
    Filed: March 21, 2018
    Date of Patent: April 2, 2019
    Assignee: Firmenich SA
    Inventors: Christian Vial, Roger Leslie Snowden
  • Transdermal administration of tamsulosin
    Patent number: 10238612
    Abstract: In an aspect of the invention, a composition for making a patch for the transdermal delivery of tamsulosin is provided. The composition comprises (a) at least about 1 wt % tamsulosin or a pharmaceutically acceptable salt of tamsulosin, (b) at least about 40 wt % polyisobutylene adhesive or hydrophobic synthetic rubber adhesive, (c) about 1-20 wt % of an aprotic solvent in which tamsulosin dissolves readily, (d) about 1-20 wt % of an unsaturated fatty acid or an alpha-hydroxy acid or a mixture of unsaturated fatty acids or alpha-hydroxy acids or of both unsaturated fatty acids and alpha-hydroxy acids, (e) a lipophilic permeation enhancer, and (f) a matrix modifier.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: March 26, 2019
    Assignee: Corium International, Inc.
    Inventors: Parminder Singh, Eun Soo Lee, Amit K. Jain
  • Particles for use in a pharmaceutical composition
    Patent number: 10238601
    Abstract: The invention provides a method of making a composition for inhalation which includes the step of mixing particles of additive material having a diameter of not more than 2 ?m with active particles, wherein the additive material is suitable for promoting the dispersal of active particles upon aerolisation of a dry powder in a dry powder inhaler.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: March 26, 2019
    Assignee: VECTURA LIMITED
    Inventors: John Nicholas Staniforth, David Alexander Vodden Morton
  • Multifunctional nutritional adjuvant chemical composition for use in agriculture
    Patent number: 10238104
    Abstract: The invention discloses herein a multifunctional nutritional adjuvant chemical composition for use in agriculture with water comprises pH modifying complex matrix, pH indicators, surfactants, penetrating agents, auxiliary chemicals and solvent; having multiple uses in agriculture such as pH corrector, auto pH indicator, wetting agent adjuvant, plants immune system activator, plant defense mechanism enhancer, nutrient supplement and plant growth hormone provider. The invention further discloses the process for preparation of said multifunctional nutritional adjuvant chemical composition.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: March 26, 2019
    Inventor: Suunil Sudhakar Chaudhry
  • Sprayable, aqueous alcoholic microbicidal compositions comprising zinc ions
    Patent number: 10238105
    Abstract: Disclosed are pressurized surface treatment compositions which impart a microbicidal benefit to treated surfaces which compositions comprise (or in certain preferred embodiments may consist essentially of, or may consist of): a zinc ion source material which releases zinc ions into the treatment composition, preferably a source of Zn++ ions, at least lower alkyl aliphatic monohydric alcohol which independently of other constituents present exhibits a microbicidal effect, a propellant; and, water. The compositions may further optionally include one or more further optional constituents such as a detersive surfactant and/or minor amounts of one or more constituents which impart one or more advantageous technical or aesthetic benefits to the compositions, including one or more detersive surfactants wherein the compositions have pH of at least 5.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: March 26, 2019
    Assignee: RECKITT BENCKISER LLC
    Inventors: Frank Apollo, John Diemer, Mohammad Khalid Ijaz, Yun-Peng Zhu
  • Carbonates of alcohol alkoxylates as adjuvants for crop protection
    Patent number: 10238106
    Abstract: The present invention relates to an agrochemical composition comprising a pesticide and an alkoxylate of the formula (I) as defined below. The invention further relates to said alkoxylate. The invention further relates to a method of preparing said composition by bringing the alkoxylate and the pesticide into contact. Finally, the invention relates to a method of controlling phytopathogenic fungi and/or undesired plant growth and/or undesired insect or mite attack and/or for regulating the growth of plants, wherein said composition is allowed to act on the respective pests, their environment or the crop plants to be protected from the respective pest, on the soil and/or on undesired plants and/or on the crop plants and/or on their environment; and to seed containing said composition.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: March 26, 2019
    Assignee: BASF SE
    Inventors: Bjorn Thomas Hahn, Rainer Berghaus, Martin Semar, Hans-Christian Raths
  • High-strength testosterone undecanoate compositions
    Patent number: 10226473
    Abstract: The present disclosure is drawn to pharmaceutical compositions and oral dosage capsules containing testosterone undecanoate, as well as related methods. The capsule includes a capsule shell and a capsule fill. The capsule fill can include a solubilizer and about 14 wt % to about 35 wt % testosterone undecanoate based on the total capsule fill. The oral dosage capsule is such that when a single oral administration to a male subject of one or more capsules with a total testosterone undecanoate daily dose of about 350 mg to about 650 mg it provides a ratio of serum testosterone Cmax to serum testosterone Cave of about 2.7 or less. In yet another embodiment, a method for providing a serum concentration of testosterone within a target serum testosterone concentration Cave range for a male subject is provided.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: March 12, 2019
    Assignee: Lipocine Inc.
    Inventors: Chandrashekar Giliyar, Basawaraj Chickmath, Nachiappan Chidambaram, Mahesh V. Patel, Srinivansan Venkateshwaran
  • Cosmetic composition comprising hydrophilic organosilanes
    Patent number: 10219992
    Abstract: The present disclosure relates to cosmetic compositions comprising an organosilane (A) having the formula: (R1)n(R2O)(3-n)SiR3O(CH2CH2O)a(C3H6O)bR4 where n is 1, 2, or 3, a?1, b may vary from 0 to 30, with the proviso a?b, R1 is a hydrocarbon group containing 1 to 12 carbon atoms, R2 is hydrogen or an alkyl group containing 1 to 6 carbon atoms, R3 is a divalent hydrocarbon group containing 2 to 12 carbon atoms, R4 is hydrogen, R1, or an acetyl group; and a cosmetic ingredient (B), and optionally in a cosmetically acceptable medium.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: March 5, 2019
    Assignee: Dow Corning Corporation
    Inventors: Michael Salvatore Ferritto, Lenin James Petroff
  • Hydrophilic filtration during manufacture of vaccine adjuvants
    Patent number: 10213383
    Abstract: An improved method for the manufacture of an oil-in-water emulsion involves three procedures: (i) preparation of a preliminary emulsion; (ii) micro fluidization of the preliminary emulsion to reduce its droplet size; and (iii) filtration of the microfluidized emulsion through a hydrophilic membrane. The emulsions are useful as vaccine adjuvants.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: February 26, 2019
    Assignee: NOVARTIS AG
    Inventors: Gottfried Kraus, Robert Eskes
  • Herbicidal compounds
    Patent number: 10206394
    Abstract: The present invention relates to a compound of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11 and G are as defined herein; and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. These compounds are suitable for use as herbicides. The invention therefore also relates to a method of controlling weeds, especially grassy monocotyledonous weeds, in crops of useful plants, comprising applying a compound of formula (I), or a herbicidal composition comprising such a compound, to the plants or to the locus thereof.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: February 19, 2019
    Assignee: SYNGENTA PARTICIPATIONS AG
    Inventors: Alan Joseph Hennessy, Shuji Hachisu, Jeffrey Steven Wailes, Nigel James Willetts, Ian Stuart Cloudsdale, Janice Black, Emma Briggs, Suzanna Jane Dale
  • Dry powder formation using a variably constrained, divided pathway for mixing fluid streams
    Patent number: 10206873
    Abstract: Methods of making a dry powder, comprise (a) delivering a liquid solution or suspension and a second, immiscible fluid to a flow path, (b) transporting the liquid solution or suspension and the immiscible fluid along the flow path, wherein the flow path includes two or more flow passages of different diameters, at least one flow divider which divides and diverts the flowing mixture into at least two separate passages, wherein the separate passages subsequently intersect to combine their respective flows into a single flowing stream, (c) rapidly reducing the pressure of the single flowing stream, whereby droplets are formed, and (d) passing the droplets through a flow of inert drying gas to form a dry powder. A nebulizing nozzle includes an inlet, a flow path as described, and a restrictor nozzle outlet.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: February 19, 2019
    Assignee: COLORADO CAN LLC
    Inventors: Xuno Gildelamadrid, Robert E. Sievers