Abstract: Systems and methods for treating an aneurysm in accordance with embodiments of the present technology include intravascularly delivering an occlusive member to an aneurysm cavity and deforming a shape of the occlusive member via introduction of an embolic element to a space between the occlusive member and an inner surface of the aneurysm wall.

Abstract: Disclosed are devices and methods for delivering several sutures accurately and simultaneously around the perimeter of an annular prosthetic device (prosthetic heart valve, annuloplasty ring, etc.) to secure the prosthetic device within a native heart valve region. Devices can comprise a proximal handle portion including an actuator and a distal suturing portion including several curved and straight needles arrayed around the shaft axis. The straight needles and the curved needles are configured to simultaneously guide a plurality of sutures through the native tissue and through the annular prosthetic device. The actuator can cause the straight needles to move axially relative to the curved needles and can also cause the curved needles to rotate, such that the motions are coordinated to simultaneously place all the sutures.

Abstract: A device includes an elongated hollow member having an open distal end for receiving tissue therein and at least one exterior groove for loading at least one ligation band thereon. The device also includes a band deployment sleeve slidable over the exterior of the hollow member and configured to move from a radially expanded position to a radially contracted position in which, when the band deployment sleeve slides longitudinally over the hollow member, the distal portion engages the at least one ligation band. A closing sleeve slidable over the exterior of the band deployment sleeve is configured to constrain the distal portion from the radially expanded position into the radially contracted position. Retracting the closing sleeve proximally over the distal portion of the band deployment sleeve releases the distal portion from the radially contracted position into the radially expanded position.

Abstract: An expandable medical sheath can include a sheath body having a lumen that extends between proximal and distal ends of the sheath. The sheath can have first and second members where the first member has a different elastic modulus than the second member such that one provides elasticity to the sheath and the other provides column strength. The first and second members can be coupled together in alternating sections to form the tubular sheath or the stiffer members can be embedded in the elastic member along all or a portion of the longitudinal length of the sheath. The sheath can automatically move to an expanded state to allow a larger diameter medical device to pass through the lumen, and once through the sheath can automatically return to its initial diameter.

Abstract: In some examples, a catheter includes an elongated body including a proximal portion and a distal portion. The elongated body includes an inner liner, an outer jacket, a structural support member positioned between at least a portion of the inner liner and at least a portion of the outer jacket, and an expandable member coupled to the structural support member at the distal portion of the elongated body. The expandable member may be configured to expand radially outward, e.g., to engage a clot within vasculature of a patient.

Abstract: This disclosure enables various threading devices (e.g., suturing devices) that can sequentially send a plurality of carriers (e.g., needle caps, sleeves) to an object (e.g., animate, inanimate, human tissue, organ tissue, heart tissue) or sequentially receive a plurality of carriers (e.g., needle caps, sleeves) from an object (e.g., animate, inanimate, human tissue, organ tissue, heart tissue). For example, some threading devices can sequentially send some carriers in a relatively rapid succession or some threading devices can sequentially receive some carriers in a relatively rapid succession.

Abstract: An automatic needle mover for moving a medical threaded needle includes: two shafts extending in the same direction and slidable relative to each other along a longitudinal direction; a needle-holding portion provided on one end side of the second shaft; a needle-receiving portion provided on one end side of the first shaft; and a handle serving as a control portion for controlling the sliding of the two shafts. The needle-holding portion has a first claw portion protruding in a direction intersecting the longitudinal direction of the shafts. The needle-receiving portion has a second claw portion protruding in a direction intersecting the longitudinal direction of the shafts. As a result of the sliding of the two shafts, the needle-holding portion and the needle-receiving portion become close to each other and a straight needle held by the needle-holding portion can be press-fitted into the needle-receiving portion.

Abstract: A surgical instrument configured to cut tissue includes an outer member and an inner member at least partially received within the outer member. The outer member includes a cutting window near a distal end thereof. A driving assembly is coupled to the inner member and configured to cause the inner member to rotate around and move along a longitudinal axis of the outer member. A controller is configured to control the driving assembly to control at least one of an angular position, an angular velocity, or an angular acceleration of the inner member according a plurality of piecewise continuous profiles. The initial and final angular velocities of the inner member are zero, and the inner member cuts tissue extending into the cutting window.

Abstract: The present disclosure relates to an explantation assembly for retrieving an intracorporeal capsule implanted in a tissue of a patient comprising a first tube and a second tube. The first tube comprises a snare and a tissue. The second tube is configured to interact with the snare of the first tube and configured to be attached to the tissue of the patient.

Abstract: A drill guide fixture may be configured to prepare a skull for attachment of a cranial insertion fixture. The drill guide fixture may include a central drill guide and a bone anchor guide at a base of the drill guide fixture. The central drill guide may define a central drill guide hole therethrough, wherein the central drill guide hole has a first opening at a base of the drill guide fixture and a second opening spaced apart from the base of the drill guide fixture. The bone anchor drill guide may define a bone anchor drill guide hole therethrough, and the bone anchor drill guide hole may be offset from the central drill guide hole in a direction that is perpendicular with respect to a direction of the central drill guide hole. Related cranial insertion fixtures, robotic systems, and methods are also discussed.

Abstract: Disclosed herein are compositions comprising containers and silk elements. Disclosed herein are methods of regenerating an at least partially severed nerve cell. Disclosed herein are compositions for regenerating an at least partially severed nerve cell.

Abstract: A robotic surgery system includes an orienting platform, a support linkage movably supporting the orienting platform, a plurality of surgical instrument manipulators, and a plurality of set-up linkages. Each of the manipulators includes an instrument holder and is operable to rotate the instrument holder around a remote center of manipulation (RC). At least one of the manipulators includes a reorientation mechanism that when actuated moves the attached manipulator through a motion that maintains the associated RC in a fixed position.

Abstract: Medical devices including balloons and balloons are provided that include an elongate body and an inflatable balloon defining a longitudinal axis, the inflatable balloon being attached to and partially surrounding at least a section of the elongate body. The medical device further includes a plurality of protrusions extending from the inflatable balloon. When the inflatable balloon is in an unstrained state, each of the plurality of protrusions extends in a first transverse direction relative to the longitudinal axis. In certain implementations, the inflatable balloon may also be configured to collapse such that, when in a collapsed state, an untextured portion of the inflatable balloon extends to a radius and the plurality of protrusions does not extend beyond the radius.

Abstract: New disposable system devises and procedure for circumcision. The new procedure is by using the clamp in the same way of using bone cutter forceps, the penis marked by skin marker below the level of coronal sulcus, the prepuce retracted, a glans protector probe introduced above the glans, the prepuce pulled back over the probe, grasped by fingers on the probe to have painless holding. The modified bone cutter with blind cut end and groove on the upper surface is applied on the level of the skin mark. Light pressure separates the glans protector from its handle, then strong pressure on prepuce applies by this modified bone cutter, a sharp knife cuts the prepuce above the instrument, left a skin tag in the groove of the instrument, a heated oval shape stainless steel coated cupper cautery pass above the grove, the heating is by gas or electricity, but the electrical current must be cut off before application, the temperature between 140-300, glans protector removed no need for any dressing.

Abstract: In an energy treatment system, circuitry temporally detects an electrical property value of an ultrasonic transducer. After an elapse of predetermined time since a power supply outputs electric power by first output power, when determining that the value has started gradual decrease, causes the power supply to change the electric power from the first output power to second output power smaller than the first output power, and after the change to the second output power, when the electrical property has gradually increased, causes the power supply to change the electric power from the second output power to third output power larger than the second output power.

Abstract: Intrasaccular flow diverter including: an interior fill braid physically inverted over itself forming a proximal inverted end and an opposite free end; and a dome braid disposed distally of and secured to the interior fill braid. Subject to application of an external mechanical force, the dome braid is transitionable between an expanded state and a compressed state. The dome braid has a proximal end with an opening defined therein through which starting at the free end the interior fill braid is passable therethrough exerting a radially outward force on the dome braid. A delivery wire is releasably detachable from the proximal inverted end of the interior fill braid. The dome braid has a stiffer profile relative to that of the interior fill braid to maintain in position within the aneurysm the dome braid as the interior fill braid is advanced therein.

Abstract: A surgical instrument, and methods for its use, is described that includes clamp heads that can be nestled within or extended from a tubular sheath by longitudinal movement of the clamp heads' tines with respect to the tubular sheath. One of the tines includes an arch that slides against a mouth and inside wall of the tubular sheath, causing the clamp heads to open or close. The clamp heads close lightly, to within a predetermined (or zero) distance from one another, gently grasp an ultrathin polymer substrate seeded with cells, and pulls it within the sheath such that the substrate curls and folds to protect the cells.

Abstract: A method is provided for operating a powered surgical stapler having a motor unit, a controller, and a stapling assembly having a plurality of movable members that are actuatable longitudinally by the motor unit to clamp, staple, and cut tissue. The controller determines that a movable member of the stapling assembly is in a first predetermined position, and then executes an actuation algorithm to activate the motor unit to actuate the movable member longitudinally from the first predetermined position toward a second predetermined position. The controller observes an actual longitudinal displacement of the movable member between the first and second predetermined positions. The controller compares the actual longitudinal displacement to an expected longitudinal displacement and determines that the actual longitudinal displacement differs from the expected longitudinal displacement by a difference value. The controller then adjusts the actuation algorithm based on the difference value.

Abstract: A hybrid endoprosthetic device comprises a stented tubular part and a branched tubular body connected such that a main lumen of the stented tubular part communicates with a main lumen of the branched tubular body. The branched tubular body has multiple branch lumens for connection with natural vessels of the vasculature, and includes at least one branch lumen for access to facilitate delivery and implantation of the hybrid endoprosthetic device by an endovascular step in a hybrid surgical procedure. The hybrid endoprosthetic device is configured to replace a part of the aorta and common iliac artery. A delivery system for use with the device is also disclosed.

Abstract: An example implant can have a tubular braid. The tubular braid can have an intrasaccular section, an intravascular section, a pinched section, and a predetermined shape. In the predetermined shape, the intrasaccular section can have a sack and an opening. The pinched section can be positioned approximate the opening. The intravascular section can be substantially disk shaped and positioned to occlude the opening. The tubular braid can be movable from a collapsed shape sized to traverse a catheter to an implanted shape based at least in part on the predetermined shape. In the implanted shape, the intrasaccular section of the braid can be sized to be positioned within an aneurysm's sac and the intravascular section of the braid can be sized to appose a blood vessel wall approximate an aneurysm's neck.