Patents Examined by Monique T. Cole
  • Use of unsaturated esters as perfuming ingredients
    Patent number: 6924262
    Abstract: The compound of formula in which the wavy line represents a bond having a configuration of the type (Z) or (E), or a mixture of the two configurations; R1 represents a hydrogen atom, a C1 to C4 linear or branched alkyl radical, a methoxy or ethoxycarbonyl radical, or an aryl radical, and R2 represents a methyl or ethyl group, possess interesting organoleptic properties and can be advantageously used for the preparation of perfuming compositions to which it gives, in particular, a very natural connotation of the pear type.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: August 2, 2005
    Assignee: Firmenich SA
    Inventor: Christian Margot
  • Process for making spiro isobenzofuranone compounds
    Patent number: 6924291
    Abstract: This invention relates to a process for making spiro isobenzofuranone compounds by coupling of an aminopyrazine fragment with a spirolactone piece.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: August 2, 2005
    Assignee: Merck & Co., Inc.
    Inventors: Zhiquo Jake Song, Matthew Mangzhu Zhao
  • Detection method of proteins on polyacrylamide gels using a dye composition as a silver ion sensitizing agent and the dye composition for the same
    Patent number: 6916663
    Abstract: The present invention relates to a method for detecting proteins on polyacrylamide gels, comprising the steps of sensitizing the proteins with a dye composition comprising an acidic organic dye as a silver ion sensitizing agent, and optionally, a basic organic dye as an auxiliary agent, and washing them, and then silver staining complexes of the protein-dye, and to the dye composition for the same.
    Type: Grant
    Filed: October 11, 2002
    Date of Patent: July 12, 2005
    Assignees: EZ Biopaq Co., Ltd.
    Inventor: Jung-Kap Choi
  • Process for the preparation of 15-pentadecanolide
    Patent number: 6914109
    Abstract: The invention relates to a process for the preparation of 15-pentadecanolide by hydrogenating 15-pentadecenolide and to its use.
    Type: Grant
    Filed: March 18, 2002
    Date of Patent: July 5, 2005
    Assignee: Symrise GmbH & Co. KG
    Inventors: Walter Kuhn, Oskar Koch, Hans-Ulrich Funk, Gerhard Senft
  • Fragrance composition containing 3-(3-hexenyl)-2-cyclopentenone
    Patent number: 6903067
    Abstract: An excellent fragrance compound having high palatability. A 3-(3-hexenyl)-2-cyclopentenone represented by a general formula (1) (wherein wavy line represents a double bond cis-form and/or trans-form) is used as an active ingredient of scent and mixed in a small amount with fragrance compositions, cis-jasmone and/or various materials to be scented. Since the above compound has a characteristic fragrance quality and high palatability, it is markedly useful as a scenting component of various fragrances and cosmetics, sanitation materials and the like.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: June 7, 2005
    Assignee: Takasago International Corporation
    Inventors: Hiroyuki Matsuda, Kenji Maruyama
  • Computerized method and apparatus for analyzing amino acids
    Patent number: 6900060
    Abstract: A method for analyzing a plurality of amino acids in a fluid sample by a user is provided comprising the steps of introducing the sample into a buffer solution, passing the sample in the buffer solution through a separation column and setting a lithium ion concentration in the buffer to no more than 0.3 mols/L up to a time before ?-aminoisobutyric acid (?-AiBA) is eluted.
    Type: Grant
    Filed: June 13, 2001
    Date of Patent: May 31, 2005
    Assignee: Hitachi, Ltd.
    Inventors: Yoshio Fujii, Masahito Ito, Kimiyoshi Koda
  • Composition of menthol and menthyl lactate, its preparation method and its applications as a cooling agent
    Patent number: 6897195
    Abstract: Disclosed here is a composition containing menthol and menthyl lactate, and its preparation method and its applications as a cooling agent and a flavoring agent. The present invention provides a composition characterized in that it comprises menthol and menthyl lactate in a ratio by weight in the range of 1:4˜4:1 and the corresponding crystallization point is below room temperature of 25° C. Such composition has the advantages of being liquid at room temperature; easy to use as a cooling agent or a flavoring agent; no need to use heat to melt menthol and menthyl lactate, which not only saves time, money and heating equipment, but also simplifies manufacturing process and can be used in cold processes at room temperature.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: May 24, 2005
    Assignee: Nanjing Zhongshi Chemical Co.
    Inventors: Evelyn G. Su, Chang-Guo Wang
  • Macrocylic musk composition, organoleptic uses thereof and process for preparing same
    Patent number: 6894020
    Abstract: Described are mixtures consisting essentially of oxomacrocyclic compounds containing greater than about 40 weight % ?3-cyclotetradecen-1-one and greater than about 40 weight % cyclotetradecanone and less than about 5 weight %, of ?2-cyclotetradecen-1-one, perfumery uses thereof and chemo-selective catalytic hydrogen process for preparing same by hydrogenating mixtures containing significant concentrations, greater than 15 weight %, of ?2-cyclotetradecen-1-one. The oxocarbocyclic compound-containing mixtures have advantageous musk aroma imparting, augmenting and enhancing perfumery properties causing the mixtures to be useful in perfume compositions, perfumed articles and perfumed polymers, including particles and fibers produced therefrom.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: May 17, 2005
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Braja Dulal Mookherjee, Anubhav P. S. Narula, Michael G. Monteleone, Robert W. Trenkle
  • Method and apparatus for rapid screening of volatiles
    Patent number: 6881585
    Abstract: In one embodiment, the present method includes the steps of introducing a volume of a sample into a vapor delivery line and volatilizing at least a portion of the volume as it is carried through the vapor delivery line. At least a portion of the volatilized volume contacts a sensor element, which produces a signal that is monitored to reveal information about the sample. All components upstream of the sensor element are substantially free of sorbent materials so that the sample volume does not contact a substantially sorbent material before contacting the sensor element.
    Type: Grant
    Filed: March 6, 2000
    Date of Patent: April 19, 2005
    Assignee: General Electric Company
    Inventors: Radislav Alexandrovich Potyrailo, James Claude Carnahan, Ralph Joseph May, John Patrick Lemmon
  • Oxime as perfuming ingredient
    Patent number: 6872697
    Abstract: The present invention relates to the use as a perfuming ingredient of 2-methyl-3-hexanone-oxime of formula in which the wavy line represents a bond having a configuration of the type (Z) or (E) or a mixture of the two configurations.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: March 29, 2005
    Assignee: Firmenich SA
    Inventors: Pierre-Alain Blanc, Piero Fantini, Peter Fankhauser
  • Perfume compositions
    Patent number: 6869923
    Abstract: The present invention relates to a perfume composition for delivery of high impact accord perfume ingredients, encapsulated embodiments of such compositions and their use in laundry and cleaning applications.
    Type: Grant
    Filed: June 4, 1999
    Date of Patent: March 22, 2005
    Assignee: Procter & Gamble Company
    Inventors: Philip Andrew Cunningham, Michael Green, Allan Campbell McRitchie
  • Trimethyldecenyl compounds
    Patent number: 6867175
    Abstract: A Compound corresponding to formula (I): wherein X is a group selected from the group consisting of —CHO, —CN, —CH?NOH, and —CH2OH, and wherein the C?C double bond assumes a Z or E configuration.
    Type: Grant
    Filed: April 28, 2001
    Date of Patent: March 15, 2005
    Assignee: Kao Corporation
    Inventors: Thomas Markert, Theo Ten Pierik, Werner Faber
  • Method for measuring concentration of solution and method of urinalysis using the same
    Patent number: 6867046
    Abstract: The present invention provides a method for measuring concentration of a solution, in which an acid is mixed in a sample to be detected to reduce the variations in pH, and the mixture is heated up to not more than 80° C. to measure the transmitted light and/or scattered light power. The present invention also provides a method of urinalysis in which the protein concentration is measured after measuring the angle of rotation. Herewith, in the method in which the sample to be detected is heated to coagulate protein, and the protein concentration is measured from the degree of opacification resulting therefrom, it is possible to reduce the influence of the pH of the sample to be detected, and to decrease the heating temperature.
    Type: Grant
    Filed: December 19, 2000
    Date of Patent: March 15, 2005
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventor: Tatsurou Kawamura
  • Method for obtaining increased particle concentration for optical examination
    Patent number: 6867049
    Abstract: The present invention relates to a method and apparatus for analyzing a blood or other biological fluid sample in a quiescent state, whereby particulate constituents of biological samples that contain sparse populations of interesting cellular species can be enumerated and inspected using an optical scanning instrument. Specifically, this invention relates to a method and apparatus for obtaining increased cellular or particulate concentrations within the use of said optical scanning method.
    Type: Grant
    Filed: September 27, 2000
    Date of Patent: March 15, 2005
    Assignee: Becton, Dickinson and Company
    Inventors: Brian G. Scrivens, Dwight Livingston, Robert S. Frank, Klaus W. Berndt
  • Cyclic ketals, fragrance compositions containing the same and methods of using the same
    Patent number: 6864225
    Abstract: Compounds of the general formula (I) are described: wherein each of R1, R2, R3, R4, R5 and R6 independently represents a substituent selected from the group consisting of hydrogen, methyl, ethyl, n-propyl, and isopropyl; an wherein x represents either 0 or 1. The compounds are useful as fragrances and as added components in fragrance blends. Methods of improving the harmony, emanation, naturalness an staying power of other fragrance ingredients by the addition of such compounds are also described.
    Type: Grant
    Filed: April 28, 2001
    Date of Patent: March 8, 2005
    Assignee: Kao Corporation
    Inventors: Thomas Markert, Theo Ten Pierik, Werner Faber
  • Pro-fragrances
    Patent number: 6861402
    Abstract: The present invention relates to fragrance delivery systems which comprise: A) from about 0.01% by weight of a pro-fragrance component which comprises pro-fragrances or pro-accords selected from at least two of the following: i) aldehyde and ketone releasing pro-fragrances, preferably an oxazolidine pro-fragrance; ii) ?-amino pro-fragrances; and iii) orthoester pro-accords; and B) the balance carries and others adjunct ingredients.
    Type: Grant
    Filed: May 31, 2000
    Date of Patent: March 1, 2005
    Assignee: The Procter & Gamble Company
    Inventors: Gregory Scot Miracle, Lon Montgomery Gray
  • Pro-perfume compositions and substrate-treating products and methods using them
    Patent number: 6858575
    Abstract: Disclosed herein are pro-perfume compositions comprising the Michael Addition reaction product of a primary and/or secondary amine compound with an unsaturated ester, acid or nitrile perfume compound. Pro-perfumes made from this selected type of reaction product provide a desirable and prolonged odor benefit to surfaces, e.g., fabrics and hard surfaces, contacted therewith. Such pro-perfumes are also utilized in a wide variety of substrate-treating products and methods.
    Type: Grant
    Filed: November 26, 2002
    Date of Patent: February 22, 2005
    Assignee: Procter & Gamble Company
    Inventors: Johan Smets, Rafael Trujillo, Christophe Laudamiel
  • Dilutions in high throughput systems with a single vacuum source
    Patent number: 6858185
    Abstract: Flow rates in a microfluidic device are modulated after performing serial dilutions by flow reduction channels that draw fluid from the main channel, thus reducing the flow rate. The reduction in flow rate and/or use of smaller dimension channels allow reduced reagent consumption. In addition, multiple flow reduction channels are used for multiple concentration measurements and for performing multiple assays simultaneously on a single sample. Also included are microfluidic devices and integrated systems for performing assays using serial dilutions, single pressure sources, multiple concentration measurements, and reduced reagent consumption. Devices comprising flow reduction channels are also used to suppress pressure perturbations from spontaneous injection.
    Type: Grant
    Filed: August 23, 2000
    Date of Patent: February 22, 2005
    Assignee: Caliper Life Sciences, Inc.
    Inventors: Anne R. Kopf-Sill, Steven A. Sundberg, Andrea W. Chow, Claudia L. Poglitsch
  • Process for making perfume containing surfactant compositions having perfume burst when diluted
    Patent number: 6858574
    Abstract: The present invention relates to a process for preparing or selecting compositions having a fragrance burst of at least 20% relative to a product before dilution. The composition is selected such that perfume and surfactant in said composition yields a calculated “Perfume Burst Index” (PBI) value of greater than 3 as per algorithm defining the PBI.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: February 22, 2005
    Assignee: Unilever Home & Personal Care USA, division of Conopco, Inc.
    Inventors: Lin Yang, Judith Lynne Kerschner
  • Rapid assay for testing overall oxidative stress
    Patent number: 6852541
    Abstract: The invention relates to an assay for testing oxidative stress of a subject by measurement of oxidants in biological fluids such as urine, plasma, bioreactor medium and respiratory aspirants. There is provided a method of determining oxidative stress in a mammalian subject. The method comprises: obtaining a sample of a biological fluid from the subject; mixing the biological fluid with a ferrous reaction reagent; incubating the biological fluid and the reaction reagent; and detecting a colored reaction product. There is further provided a ferrous reaction reagent suitable for use in assaying oxidative stress, said reaction reagent comprising 2-deoxyglucose, TBA, EDTA, and ferrous sulfate, and being substantially free of ascorbic acid.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: February 8, 2005
    Inventors: Adebola Obayan, Bernhard H. Juurlink