Abstract: The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them. More particularly, the present invention relates to novel &bgr;-aryl-&agr;-oxysubstituted alkylcarboxylic acids of the general formula (I), their derivatives, their analogs, their tautomeric forms, their stereosomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates and pharmaceutically acceptable compositions containing them.
Type:
Grant
Filed:
March 27, 2001
Date of Patent:
December 16, 2003
Assignees:
Dr. Reddy's Laboratories Limited, Reddy-Cheminor Inc.
Abstract: Substituted or 6,7-ring fused 1,2,3-triazolo[1,5-&agr;]-pyrimidine derivatives are selective ligands for GABAA receptors useful in the treatment of disorders of the central nervous system, including anxiety and convulsions.
Type:
Grant
Filed:
November 8, 2000
Date of Patent:
January 8, 2002
Assignee:
Merck Sharp & Dohme Ltd.
Inventors:
Howard Barff Broughton, Jose Luis Castro Pineiro, Ian James Collins, Karl Richard Gibson, Michael Rowley, Leslie Joseph Street
Abstract: New 3-substituted 3H-2,3-benzodiazepine derivatives of general formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7 and n have the meanings indicated in the description, their production as well as their use as pharmaceutical agents are described.
Type:
Grant
Filed:
January 31, 1997
Date of Patent:
May 26, 1998
Assignee:
Schering Aktiengesellschaft
Inventors:
Tamas Hamori, Istvan Tarnawa, Sandor Solyom, Pal Berzsenyi, Erzsebet Birkas, Ferenc Andrasi, Istvan Ling, Tibor Hasko, Gabor Kapus, Emese Csuzdl, Marta Szollosy, Franciska Erdo, Antal Simay, Gabor Zolyomi