Abstract: A wearable device is provided. The wearable device includes an electronic component and an encapsulant. The encapsulant includes a low-penetrability region encapsulating the electronic component and a high-penetrability region physically separated from the electronic component.

Abstract: The invention is method comprising the use of an external photic stimulator treat and/or prevent pain in a subject, such as migraine headache, dental pain, and/or other sources of cranial pain. The presently disclosed method includes treating the pain externally through the cheek, over the zygomatic arch and area of the trigeminal ganglion. The external photic stimulation is believed to inhibit excessive firing of trigeminal ganglion circuits, preventing the excessive expression of calcitonin gene-related peptides and/or other inflammatory manifestations of the pain.

Abstract: Methods and apparatuses for treating a patient having a brain lesion (e.g., a stroke patient) by applying a charge-balanced, low-frequency alternating current stimulation (ACS) to a region of the patient's brain immediately before and/or during a directed movement. The charge-balanced, low-frequency ACS may have a depolarizing phase that is slower than the hyperpolarizing phase (e.g., the depolarizing phase may have a frequency of 15 Hz or less and the hyperpolarizing phase with a frequency greater than 15 Hz). The ACS stimulation field may be greater than 1.5 V/m. The ACS may be applied during a preferred excitation phase.

Abstract: A method to measure sound-producing behaviors of a subject with a power- and bandwidth-limited electronic device that includes a processor includes measuring, by a microphone communicatively coupled to the processor, sound in a vicinity of the subject to generate an audio data signal that represents the sound. The method also includes measuring, by at least one second sensor communicatively coupled to the processor, at least one parameter other than sound to generate at least a second data signal that represents the at least one parameter other than sound. The method also includes detecting one or more sound-producing behaviors of the subject based on: both the audio data signal and the second data signal; or information derived from both the audio data signal and the second data signal.

Abstract: A method of optimizing the use of resources in treatment planning involving more than one radiation set delivered to one or more patients, the radiation sets requiring different resources, respectively, wherein the optimization is performed using an optimization problem comprising an optimization function related to the first and second sets of resources. The method may be used for optimizing one plan for one patient, or a number of plans for different patients, in such a way that the available resources are used in the best possible way.

Abstract: Disclosed are a timeline-based navigation feature and a channel selection feature. The timeline-based navigation feature allows the user to visually identify significant events during an episode and quickly navigate the display of data to those significant events. Embodiments of such feature allow a user to quickly see that there is a shock delivered, for example, and click on that part of a timeline navigator to advance the detailed display of data to that point in the episode. The data channel selection feature enables selection of display channel(s) from among a set of available data channels. Embodiments of such feature enable a selection and/or deselection of various channels for display to minimize display of extraneous data and/or to select preferred channels of data for review.

Abstract: An implantable medical device may include a plurality of electrical components connected to form operational circuitry, a canister shaped for housing the operational circuitry, and a dampening layer configured to reduce internal motion between the operational circuitry and at least one of a plurality of additional component within the canister, the dampening layer selectively disposed over the operational circuitry but not over the at least one additional component, the dampening layer providing electrical isolation to the operational circuitry, the dampening layer comprising a moldable material in direct contact with an inner surface of the canister. Methods of manufacturing such a medical device are also disclosed.

Abstract: A system and a method of performing screening tests for diagnosing a developmental condition of a human subject may include: receiving one or more profile data elements pertaining to the human subject; receiving one or more first behavioral data elements that may include information that is indicative of a behavior of a human subject from one or more data sources; analyzing the one or more first behavioral data elements in view of the one or more profile data elements to obtain a suspected impediment of development of the human subject; and presenting to the human subject a personalized test, adapted to diagnose the developmental condition of the human subject in view of the suspected impediment, to perform on a UI of a computing device according to the suspected impediment.

Abstract: A fitting algorithm for a spinal cord stimulator is disclosed, which is preferably implemented in a clinician programmer having a graphical user interface. In one example, coupling parameters indicative of coupling to neural structures are determined for each electrode in an implanted electrode array. The user interface associates different pole configurations with different anatomical targets and with different measurement techniques (subjective or objective) to gauge the effectiveness of the pole configuration at different positions in the electrode array. The pole configuration, perhaps as modified by the coupling parameters, is then steered in the array, and effectiveness is measured along with a paresthesia threshold at each position. Using at least this data, the fitting algorithm can determine one or more candidate positions in the electrode array at which a therapeutic stimulation program can be centered.

Abstract: In some embodiments, systems and methods can include a wearable device with an electrically conductive skin interface that excites the underlying nerves from a transcutaneous surface stimulator. The device may be sized for a range of user sizes with stimulation electrodes positioned to target the appropriate nerves, such as the peroneal, femoral, saphenous and/or tibial nerves. The stimulation may include burst stimulation, and involve receiving an input relating to autonomic nervous system activity of the patient.

Abstract: A functional electrical stimulation (FES) device includes electrodes arranged to apply functional electrical stimulation to a body part of the user. FES stimulation is performed by: receiving values of a set of user metrics for the user; receiving a target position of the body part represented as values for a set of body part position measurements; determining a user-specific energization pattern for producing the target position based on the received target position and the received values of the set of user metrics for the user; and energizing the electrodes of the FES device in accordance with the determined user-specific energization pattern. The determination may utilize an FES calibration database with records having fields containing: values of the set of user metrics for reference users; energization patterns; and values of the set of body part position metrics for positions assumed by the body part in response to applying the energization patterns.

Abstract: A surgical apparatus is described herein including an articulating segmented endoscopic portion including at least two segments connected by an angled rotary interface.

Abstract: Systems and methods are provided for delivering neurostimulation therapies to patients for treating chronic heart failure. A neural fulcrum zone is identified and ongoing neurostimulation therapy is delivered within the neural fulcrum zone. The implanted stimulation device includes a physiological sensor for monitoring the patient's response to the neurostimulation therapy on an ambulatory basis over extended periods of time and a control system for adjusting stimulation parameters to maintain stimulation in the neural fulcrum zone based on detected changes in the physiological response to stimulation.

Abstract: A topical nerve stimulation patch includes a substrate, a dermis conforming bottom surface of the substrate, a top outer surface of the substrate, a plurality of electrodes positioned on the patch proximal to the bottom surface and located beneath the top outer surface and coupled to the substrate, a power source and electronic circuitry embedded in the patch and located beneath the top outer surface and coupled to the substrate. The electronic circuitry is configured to generate an electrical stimuli via the electrodes that comprise a plurality of pulses of a target output voltage, and includes a controller configured to generate a first pulse at a first output voltage that is less than the target output voltage and generate a second pulse at a second output voltage that is less than the target output voltage and greater than the first output voltage.

Abstract: Presented herein are dissolution barriers for use with tissue-stimulating prostheses. As described further below, a tissue-stimulating prosthesis comprises a stimulating assembly including an elongate insulating carrier member and a plurality of electrode contacts disposed along the carrier member. A continuous dissolution barrier is disposed on the surface of the stimulating assembly so as to substantially encapsulate/enclose the plurality of electrode contacts and the carrier member. The continuous dissolution barrier is configured to inhibit in situ dissolution of the plurality of electrode contacts.

Abstract: An intracardiac pacemaker system is configured to produce physiological atrial event signals by a sensing circuit of a ventricular intracardiac pacemaker and select a first atrial event input as the physiological atrial event signals. The ventricular intracardiac pacemaker detects atrial events from the selected first atrial event input, determines if input switching criteria are met, and switches from the first atrial event input to a second atrial event input in response to the input switching criteria being met. The second atrial event input includes broadcast atrial event signals produced by a second implantable medical device and received by the ventricular intracardiac pacemaker.

Abstract: This disclosure provides one or more computer-readable media having computer-executable instructions for performing a method. The method includes storing geometry data representing a primary geometry of a cardiac envelope that includes nodes distributed across the cardiac envelope and geometry of a body surface that includes locations where electrical signals are measured. The body surface is spaced apart from the cardiac envelope. The method also includes perturbing the primary geometry of the cardiac envelope a given distance and direction to define the perturbed geometry of the cardiac envelope including nodes spaced from the nodes of the primary geometry. The method also includes computing reconstructed bipolar electrical signals on the nodes of the primary cardiac envelope based on the electrical signals measured from the body surface and the geometry data, including the primary and perturbed geometries of the cardiac envelope.

Abstract: The present technology provides systems and methods for directly suppressing nerve cells by delivering electrical stimulation having relatively long pulse widths and at amplitudes below an activation threshold of the nerve cells. For example, some embodiments include delivering a therapy signal having individual pulses with pulse widths of between about 5 ms and 100 ms. Directly suppressing the nerve cells is expected to reduce the transmission of pain signals.

Abstract: A graphical representation may be displayed including at least a plurality of transducer graphical elements, each transducer graphical element of the plurality of transducer graphical elements representative of a respective transducer of a plurality of transducers of a transducer-based device. A set of user input may be received including an instruction set to reposition a first transducer graphical element in a state in which the first transducer graphical element is located at a first location in the graphical representation and a second transducer graphical element is located at a second location in the graphical representation, the second location closer to a predetermined location in the graphical representation than the first location. In response to conclusion of receipt of the set of user input, the first transducer graphical element may be repositioned from the first location in the graphical representation to the predetermined location in the graphical representation.

Abstract: The present disclosure relates to a fiber and a laser probe assembly with a probe tip that houses the fiber. In certain aspects, the fiber includes a core, an outer cladding surrounding the core, and an end face at a proximal and/or distal end of the fiber. The core is configured to transmit a laser light beam while the core and the outer cladding are both configured to transmit an illumination light. In certain aspects, a surface area of the end face corresponding to a cross-section of at least the outer cladding is treated with a roughening or polishing process to modulate an illumination light output angle of the fiber. Using a fiber that is configured to transmit a laser light beam as well as a wide-angle illumination light allows for a more compact fiber and probe tip, allowing for medical procedures that require a narrower probe.