Abstract: The subject matter of the invention is the use of organic polymers which contain inorganic anionic groups for prophylaxis and therapy of retrovirus infections in mammals.

Abstract: Fumaric acid derivatives of the formula ##STR1## wherein R.sub.1 is a hydrogen atom, a C.sub.1 -C.sub.8 alkyl group or a metallic cation, andR.sub.2 is a saturated or unsaturated aliphatic C.sub.6 -C.sub.24 alkyl group, psoralen-9-yl, retinyl, .alpha.-tocopheryl (vitamin E), calciferyl, corticosteroid-21-yl or monosaccharid-.omega.-yl; a group of fumaric acid derivatives based on glycerol, alkane diol or polyol molecules; and fumaric acid derivatives of the formula ##STR2## wherein n is an integer from to 30 to 260,R.sub.3 is a hydrogen atom or a C.sub.1 -C.sub.3 alkyl group,R.sub.4 is one of the R.sub.3 groups and n is the number of molecule repetitions, processes for their production and compositions containing same are described. These compounds are useful as drugs for the treatment of cryptogenically-caused diseases and have antisporiatic as well as antimicrobial action.

Abstract: Complexes of glycyrrhetinic acid with phospholipids are described in which the molar ratio of phospholipids to glycyrrhetinic acid is from 0.5 to 2. The phospholipids are selected from the group consisting of soy lecithins, phospholipids from bovine or swine brain or cutis, phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine in which the acyl groups can be the same or different and are mostly derived from palmitic, stearic, oleic, linoleic, linolenic acids. The phospholipid may be soy phosphatidylcholine or distearoylphosphatidylcholine. Pharmaceutical compositions and a method for producing anti-inflammatory, antiulcer and healing effects in an animal are also described.

Abstract: Total esters of alginic acid with aliphatic and araliphatic alcohols possess important bioplastic and pharmaceutical qualities and are useful in various fields including the sanitary and surgical fields.

Abstract: The present invention relates to a compound of the formula: ##STR1## wherein X is hydroxyl group or hydrogenatom, or a salt thereof. The compound (I) has an acitivity to inhibit angiogenesis, which is useful for prophylaxis and therapy of various diseases accompanying abnormally increased angiogenesis, especially of tumors.

Abstract: Naringin and naringenin are disclosed as pharmaceuticals that selectively inhibit the growth of cancer cells in the presence of normal cells. They are also effective against cancer cells that are resistant to chemotherapy or radiotherapy. It is shown that naringin and naringenin selectively contract DNA chains of tumor cells but not DNA chains of normal cells. The subject compounds also exhibit anti-viral activity. A novel method for the recovery of naringin and naringenin from natural vegetable sources is taught.

Abstract: Method for the treatment of arthritis, rheumatism and inflammation of connective tissue in which a multivalent metal ion substantially pure complex of xylan polysulphate, wherein the multivalent metal ion is selected from the group consisting of Ca.sup.2+, Mg.sup.2+, Cu.sup.2+ and Zn.sup.2+ is administered to a patient in need of such treatment.

Abstract: Novel steroid compounds which are glycoside derivatives of 14.beta.-hydroxypregnane and 17.alpha.-acetoxy-6.alpha.-methylpregnane are described. The compounds have increased receptor potency when compared to their aglycone and beneficial renal effects.

Abstract: There are disclosed a body fluid purifying material which comprises a water-insoluble compound obtained by allowing one or more kinds of a polymeric compound having hydroxyl groups to react with a compound having at least one isocyanate group, and a method for purifying a body fluid which comprises using a water-insoluble polymeric compound obtained by allowing one or more kinds of a polymeric compound having hydroxyl groups to react with a compound having at least one isocyanate compound.

Abstract: The invention relates to pharmaceutical compositions having antiendotoxic activity, comprising as the active component a fraction which can be isolated from lactulase syrup by means of absorption at a sulphonated polystyrene cation resin in the Ca.sup.2+ - form and elution with a suitable solvent. The lactulose syrup can be obtained by basic isomerization of lactose at elevated temperature, optionally in the presence of sodiumsulphite.

Abstract: The present invention relates to a sodium salt of sialosyl cholesterol. The present compound has an excellent high water solubility, and therefore the compound is very useful as a medicine to be used for treating various diseases derived from lesions of peripheral or central nerves.

Abstract: Compounds of the formula ##STR1## in which R.sup.1 represents saturated, unsaturated or anhydro desoxypentosyl, desoxyhexosyl or didesoxyhexosyl, where the OH functions of the sugar are optionally protected, andR.sup.2 represents straight-chain or branched or heterosubstituted alkyl having up to ten carbon atoms andR.sup.3 represents straight-chain or branched or heterosubstituted alkyl having up to ten carbon atoms andX represents halogens andR.sup.4 represents straight-chain or branched or heterosubstituted alkyl having up to ten carbon atoms.Such compounds are useful as highly selective cytostatics in cancer therapy.

Abstract: A conjugate formed by the covalent bonding of a prostaglandin or a similar compound thereto and a polysaccharide. The prostaglandin is selected from prostaglandin E1, prostaglandin E2, prostaglandin F2.alpha., prostaglandin I2, carbacycline and iloprost and the polysaccharide is selected from pluran, amylose, amylopectin, cellulose, dextran and hydroxyethylated starch.

Abstract: Complexes formed between aescin, cholesterol or .beta.-sitosterol and phospholipids are described. The molar ratio of phospholipids to aescin/.beta.-sitosterol or cholesterol is from 0.5 to 2. The phospholipids are selected from the group of soy or egg lecithins, phospholipids from bovine or swine brain or cutis, phosphatidylcholine, phospatidylserine, phosphatidylethanolamine in which the acyl groups may be the same or different and are mostly derived from palmitic, stearic, oleic, linoleic, linolenic acids, for instance, pharmaceutical compositions and a method for producing an anti-inflammatory effect in an animal are also described.

Abstract: Acne is treated by administering to the subject a substance which is effective in blocking glucose entry into sebaceous cells, thereby inhibiting the production of sebum by these cells. Typically, the substance is administered topically and is dissolved or suspended in an appropriate solvent. The preferred substance is phloretin, which can for example, be dissolved in propylene glycol.

Abstract: Disclosed are novel 5-C-hydroxymethylhexose compounds and their derivatives which exhibit sugar-like functionality when used in food compositions. The derivatives include stereoisomers, di-, tri-, and polysaccharides, alkyl glycosides, polyol, and alditol derivatives. Also disclosed are sugar substitute compositions and food compositions containing these compounds and their derivatives.

Abstract: New heparinic derivatives having anticalculous activity, devoid of the anticoagulant and antithrombotic activity characteristic of the heparins, obtained by treating commercial or purified or low molecular weight heparins in a basic medium, optionally in the presence of alkali metal salts and of a reducing agent. The heparinic derivatives obtained through this treatment show significant chemical-physical characteristics, in particular they present a .sup.13 C-NMR spectrum different from that of the starting heparins especially in the zone between 102 and 92 p.p.m. with a characteristic signal at 101.3 p.p.m., a specific rotatory power at 546 nm between about +15.degree. and about +40.degree. in aqueous solution, a sulfur content between about 6% and about 9%, a sulfate/carboxyl ratio between about 1.20 and about 1.70 and a content of free amino groups between about 0.4% and about 2.1%. These heparin derivatives can be useful in the treatment of the nephrolithiases.

Abstract: A method of disinfection for retroviruses which comprises contacting inanimate object in need of such treatment with a natural or synthetic oligo- or polysaccharide having at least one S-oxoacid group attached to the saccharic carbon atom through a linking group of low molecular weight.

Abstract: The synthesis of the novel fucosidase inhibitors, .beta.-L-homofuconojirimycin and related 1-.beta.-C-substituted deoxymannojirimycins, is disclosed.

Abstract: The present invention relates to ganglioside related compounds having, for example, the following formula: ##STR1## where R.sub.1 represents H or COCH.sub.3 (hereinafter abbreviated to "AC"); R.sub.2 represents H or CH.sub.3 ; and R.sub.3 represents --OH, ##STR2## These ganglioside related compounds are useful as membrane receptors, tumor markers, cell growth controlling substances, etc., and useful for immunotherapy for cancer, etc.