Abstract: The invention provides a high-throughput screening system based on multi-manipulators, and belongs to the field of biotechnology and detection equipment. A high-throughput screening system based on multi-manipulators, comprises of the first manipulator, sampler, pipette, plate washer, microplate reader, the second manipulator, centrifuge, deep-well plate library, waste shallow-well plate barrel, shallow-well plate library, waste needle plate barrel, needle library, waste deep-well plate barrel, collection box. The present invention is a combination of microbiology and mechanics. The aim of the invention is to realize the automation and intelligentization of the high throughput screening experiment, effectively improve the experimental accuracy, reliability and efficiency. It contributes to the development of high throughput screening technology for microorganisms and drugs.

Abstract: The present subject matter describes system (100) for magnetic enrichment of magnetically marked analytes. The system has capture chip (102) comprising a sample chamber (104) for holding sample having magnetically marked analytes, and a recovery chamber (106) connected to the sample chamber by a channel (202). The volume of recovery chamber is smaller than volume of sample chamber (104). The system has magnetic arrangement (108) comprising a set of magnets (110) in which each two adjacent magnets have opposite polarities facing sample chamber. Set of magnets has dimensions that at least conform to coverage area of sample chamber. The magnetic arrangement also has at least one recovery magnet (112) having dimensions conforming to coverage area of recovery chamber and on alignment, the at least one recovery magnet (112) is at a distance farthest away from the recovery chamber. The system has a linear positioner (114) for moving the magnetic arrangement.

Abstract: A device for collecting multiple samples for use by a single user while avoiding cross-contamination under adverse conditions is disclosed. A multiple sampling device comprising a single handle actuator with a trigger, connected to a shaft assembly further connected to a claw assembly for actuating a self-sealing sampling sphere in the process of collecting a desired sample, is disclosed. The sampling sphere comprises two halves that separate when the trigger and claw assembly are actuated, and close together when the trigger is released using springs on the claw assembly and sampling sphere. Additional sampling spheres are stored on the shaft assembly. In operation, once a sample is collected by one sampling sphere, the sampling sphere is exchanged with an empty sampling sphere stored on the shaft assembly.

Abstract: Disclosed is a system and method for the recycling of waste composite feed materials such as printed circuit boards (PCBs), batteries, catalysts, plastic, plastic composites such as food packaging materials, for example Tetra Pak®, mattresses, compact disks (CDs, DVDs), automobile shredder residue (ASR), electric cable wastes, liquid display panels, mobile phones of various sizes or combinations of the above using a new pyrolysis system and method.

Abstract: The invention relates to a process for moving a droplet from a first location to a second location, which droplet comprises a magnetic material disposed in an aqueous medium. The invention also relates to a droplet assembly comprising a droplet, which droplet comprises a magnetic material disposed in an aqueous medium. Various uses of the droplet assembly are also described.

Abstract: A device for manipulating magnetic particles includes a gelled medium layer and liquid layers alternately stacked in a tubular container along a longitudinal direction of the container. A magnetic particle movement portion for moving magnetic particles exists along an inner wall surface of the container, and the magnetic particle movement portion extends along the longitudinal direction of the container. At a portion where the gelled medium layer is loaded, the cross-sectional shape of the container inner wall in a plane perpendicular to the longitudinal direction of the container is non-circular, and the shape of the magnetic particle movement portion in the cross section is a curved shape or an angular shape.

Abstract: Disclosed herein are a device and method for the easy removal of selected individual wells, selected groups/strips of wells, or all strips of wells quickly and safely from a well strip plate. A well strip extractor press may include a manually pivotable well strip plate carrier having an open bottom, and an adjustable well strip extractor assembly having multiple press arms positioned to engage the bottom of a well strip plate positioned in the well strip plate carrier. A user may manually position a selection of press arms to align with those well strips that the user wishes to remove from the well strip plate.

Abstract: Devices that can transport biological materials are described. The devices incorporate capillary channeled fibers that can effectively transport living cells as well as other biological materials such as nutrients, growth factors, waste materials, etc. The devices can include a sorptive material at one end of the fibers that can improve transport of materials through the devices. The devices can differentially transport different cell types, particularly when the fibers are held in a vertical orientation. Diagnostic devices that incorporate the capillary channeled fibers are described that can be utilized to separate cell types from one another. Tissue engineering scaffolds that incorporate the capillary channeled fibers are described that can more efficiently transport materials into and out of the scaffolds.

Abstract: The present invention relates to a fluid flow device. The device includes an elongate body having a proximal end, a distal end, and a length therebetween, at least one source fluid inflow port, at least one waste fluid outflow port, at least one well inlet port positioned at the distal end of the elongate body, at least one well outlet port positioned at the distal end of the elongate body, at least one conduit connecting the at least one source fluid inflow port to the at least one well inlet port, and at least one conduit connecting the at least one waste fluid outflow port to the at least one well outlet port.

Abstract: The present disclosure describes a throughput-scalable image sensing system for analyzing biological or chemical samples is provided. The system includes a plurality of image sensors configured to detect at least a portion of light emitted as a result of analyzing the biological or chemical samples. The plurality of image sensors is arranged on a plurality of wafer-level packaged semiconductor dies of a single semiconductor wafer. Each image sensor of the plurality of image sensors is disposed on a separate packaged semiconductor die of the plurality of packaged semiconductor dies. Neighboring packaged semiconductor dies are separated by a dicing street; and the plurality of packaged semiconductor dies and a plurality of dicing streets are arranged such that the plurality of packaged semiconductor dies can be diced from the single semiconductor wafer as a group.

Abstract: Provided is a biological sensing system, including a nanowire field-effect transistor and a sensing chip. A gate terminal of the nanowire FET surrounds a gate of a silicon nanowire or a gate of a silicon nanobelt, diameter of the silicon nanowire is less than 20 nm. A sensing electrode of the sensing chip is coupled to the gate terminal of the nanowire FET. An area ratio of an electrode area of the sensing electrode to a total sensing chip area, a thickness ratio of an oxide thickness of sensing electrode to a bulk oxide dielectric film thickness of the sensing chip and a capacitance ratio of an electrode capacitor of the sensing electrode to a gate capacitor of the silicon nanowire or a gate capacitor of the silicon nanobelt are optimized by means of an equivalent circuit so that potential coupling efficiency between sensing electrode and gate is optimized.

Abstract: To accurately analyze measurement target particles in each specimen, while reducing variation in dispensing amounts of specimens which is caused by different viscosities of the respective specimens. A sample preparing apparatus 1 includes: a measurement section 2 configured to measure a specimen obtained from a specimen container 10, and obtain viscosity information relating to viscosity of the specimen; a sample preparation section 3 configured to prepare a measurement sample by aspirating the specimen from the specimen container 10, discharging the specimen into a mixing container 11, and mixing the specimen with a labeling substance in the mixing container 11; and a control section 4 configured to determine, on the basis of viscosity information, at least one of an aspiration condition for aspirating the specimen and a discharge condition for discharging the specimen, and control the sample preparation section 3.

Abstract: Systems, devices, and methods are provided that facilitate synthesis and analysis of chemical compounds on a convenient and automatable palette-based platform. Palettes utilized for analysis support a variety of functional sites, including test wells, separation devices, and test sites that have rapid thermal equilibration, on a single test fixture. This permits both the performance of a wide variety of tests and of tests with different temperature requirements or responses in parallel, on the same test fixture. Such systems, devices, and methods are particularly suitable for production and characterization of radiopharmaceuticals.

Abstract: A method for pre-positioning a coaxial sample and sheath combination includes calculating a load shape profile including a plurality of layers of substantially equal volume. The calculated load shape profile is incrementally divided into cross-sectional slices at a first set of distance coordinates along a first axis. Each cross-sectional slice transects the plurality of layers. A sample includes a number of objects residing in solution. A sample chamber is loaded with the sample by incrementally dispensing the sample in a plurality of portions along a vertical axis divided into a second set of distance coordinates proportional to the first set of distance coordinates, where each portion has a volume proportional to the cross-sectional slice at the first distance coordinate nearest in value to the second distance coordinate.

Abstract: The discrimination ability of a chemical sensing cross-reactive arrays is enhanced by constructing sensing elements in two dimensions, first in the x-y plane of the substrate, second in the z dimension so that the sensors are vertically stacked on top of one another. Stacking sensing elements on top of one another adds to the discrimination ability by enabling the characteristic measurement of how fast target chemicals are passing through the stack of sensors. The new invention also allows the ability to discriminate components in a sample mixture by separating them using their innate difference in diffusional rates. Multi-sensor response patterns at each z level of sensors and time delay information from the sample passing from one level to the next are used to generate the response vector. The response vector is used to identify individual component samples and components in a mixture sample.

Abstract: A multiwell plate cover is provided, wherein the cover comprises a frame configured for attachment to a multiwell plate; a first movable guide member having two elongated side members that extend across the width of the plate, wherein a gap between the side members is substantially equal to a diameter of a single well in the multiwell plate and wherein the first movable guide member is slidable along the length of the frame; and a second movable guide member having two elongated side members that extend across the length of the plate, wherein a gap between the side members is substantially equal to a diameter of a single well in the multiwell plate and wherein the second movable guide member is slidable along the width of the frame, wherein the first and second movable guide member are configured to move independently from each other.

Abstract: A storage apparatus includes a storage device having a first storage assembly with a plurality of first storage racks and a second storage assembly with a plurality of second storage racks surrounding the first storage racks. At least one of the first and second storage assemblies includes a removable carrier rack configured to align with a selected storage rack of the other first or second storage assembly. A protective cover device includes first and second protective cover assemblies respective disposed on top ends of the first and second storage assemblies. At least one of the first and second protective cover assemblies is openable at an area corresponding to the top of the carrier rack to permit removal of the same.

Abstract: According to one example, a system includes a heat source operable to provide an amount of energy to be used to cook a food item, and further includes one or more processors. The processors are operable to receive an indication of a requested cooking temperature, and to receive a plurality of indications of measured temperature associated with the food item at different times. The processors are further operable to determine an integral term based on differences between the requested cooking temperature and the measured temperatures, to determine a heat loss term based on the integral term, and to determine an energy adjustment based on the heat loss term. The heat source is further operable to modify the amount of energy provided by the heat source in accordance with the determined energy adjustment.

Abstract: A handling system for high throughput processing of a large volume of biological samples is provided herein. Such systems can include an array support assembly that supports multiple diagnostic assay modules in an array having at least two dimensions, a loader that loads multiple diagnostic assay cartridges within the multiple diagnostic assay modules. The array support assembly can be movable relative the loader to facilitate loading and unloading so as to provide more efficient processing.

Abstract: Disclosed is a process for treating waste plastic materials such as whole tyres, coarsely cut tyres, large plastic pieces, plastic composites such as hoses or combinations of above into gases, liquids and solids by direct heating in a pyrolysis liquid (1) such as molten salt or molten metal. The pyrolysis system is constructed such that the segregation of the light and heavy materials occurs within the pyrolysis chamber. The carbon black is segregated from the pyrolysis vapours via a cyclone and fractions of carbon black may be obtained by installing a number of cyclones in series so that different qualities of carbon black may be produced. Diesel or other oils, steel, carbon black, ZnO and synthesis gas are recovered; all of which can be feed streams to other processes. This process avoids the inefficient procedure of cutting the tyres or other plastic composites into small pieces before treatment by pyrolysis and also recovers valuable components.